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T75526Chlorfortunone A;化合物 Chlorfortunone AChlorfortunone A
Chlorfortunone A, a novel sesquiterpenoid dimer isolated from the roots of Chloranthus fortunei, inhibits transforming growth factor (TGF)-β activity [1].
价 格:¥电议型 号:T75526产 地:中国大陆
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T7549027-O-(tert-Butyldimethylsilyl)withaferin A;化合物 27-O-(tert-Butyldimethylsilyl)withaferin A27-O-(tert-
27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a), a natural withanolide known for inducing apoptosis, exhibits antiproliferative effects on HeLa, A-549, and MCF-7 human cancer cell lines, as well as on normal Vero cells [1].
价 格:¥电议型 号:T75490产 地:中国大陆
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T75425Synephrine hemitartrate;化合物 Synephrine hemitartrateSynephrine hemitartrate
Synephrine hemitartrate (Oxedrine), an alkaloid extracted from Citrus aurantium, functions as both an α-adrenergic and β-adrenergic agonist. As a sympathomimetic compound, it has applications in weight loss [1] [2].
价 格:¥电议型 号:T75425产 地:中国大陆
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T75402,5-Di-tert-butylhydroquinone2,5-二特丁基对苯二酚BHQ|||2,5-二特丁基对苯二酚
2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.
价 格:¥电议型 号:T7540产 地:中国大陆
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T75255L1SB-435495 ditartrate;化合物 SB-435495 ditartrateSB-435495 ditartrate
SB-435495 ditartrate is a potent, selective, reversible, non-covalent, and orally active inhibitor of Lp-PLA2, demonstrating an IC50 value of 0.06 nM [1] [3].
价 格:¥电议型 号:T75255L1产 地:中国大陆
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T75248Pasireotide (diaspartate);化合物 Pasireotide (diaspartate)Pasireotide (diaspartate)
Pasireotide diaspartate (SOM230), a long-acting cyclohexapeptide and somatostatin analog, enhances agonist activity across somatostatin receptor subtypes (sst1/2/3/4/5, with pK i values of 8.2, 9.0, 9.1, <7.0, and 9.9, respectively). This compound demonstrates antisecretory, antiproliferative, and proapoptotic activities [1] [2].
价 格:¥电议型 号:T75248产 地:中国大陆
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T752362’-Deoxy-2’-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine;化合物 2’-Deoxy-2’-fluoro-N3-[3-(ter
2’-Deoxy-2’-fluoro-N3-[3-(tert-butoxycarbonyl)amino]propyluridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and induction of apoptosis, among others [1].
价 格:¥电议型 号:T75236产 地:中国大陆
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T75233N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine;化合物 N3-(2S)-[2-(tert-Bu
N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine, a uridine analog, exhibits potential for antiepileptic effects. Its analogs hold promise for research into anticonvulsant and anxiolytic activities, besides contributing to the development of novel antihypertensive agents [1].
价 格:¥电议型 号:T75233产 地:中国大陆
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T75130Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br;化合物 Glucocorticoid receptor agonist-1 phospha
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Br is a drug-linker conjugate for antibody-drug conjugates (ADCs), serving as a reaction reagent in the creation of anti-CD40 antibody agent conjugates [1].
价 格:¥电议型 号:T75130产 地:中国大陆
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T7503LUpadacitinib tartrate;化合物 T7503LABT 494|||ABT-494|||ABT494;ABT 494|||ABT-494|||ABT494
Upadacitinib is a potent and selective JAK inhibitor. Upadacitinib is approximately 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. Upadacitinib demonstrates efficacy in rat arthritis models.
价 格:¥电议型 号:T7503L产 地:中国大陆
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T75016Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal;化合物 Glucocorticoid receptor agonist-1 phosph
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Mal functions as a glucocorticoid receptor agonist, utilized in the formulation of anti-CD40 antibody agent conjugates (ADC). It serves as a research tool for exploring inflammation and immune regulation [1].
价 格:¥电议型 号:T75016产 地:中国大陆
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T74987TAMRA alkyne, 6-isomer;化合物 TAMRA alkyne, 6-isomerTAMRA alkyne, 6-isomer
TAMRA alkyne, 6-isomer, a variant of the xanthene dye TAMRA, known for its orange emission, serves as a linker specifically designed for oligonucleotide labeling and amino acid sequencing. This isomer incorporates alkyne groups, enabling copper-catalyzed Click Chemistry reactions with azides [1].
价 格:¥电议型 号:T74987产 地:中国大陆
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T74937Sirt2-IN-7;化合物 Sirt2-IN-7Sirt2-IN-7
Sirt2-IN-7 (compound 22) is a selective SIRT2 inhibitor with an IC50 of 178.2 nM and a Ki of 154.3 nM, utilized in cancer research [1].
价 格:¥电议型 号:T74937产 地:中国大陆
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T74894SIRT1/2/3-IN-1;化合物 SIRT1/2/3-IN-1SIRT1/2/3-IN-1
SIRT1/2/3-IN-1 (compound 10) is a potent, selective, and cell-permeable inhibitor targeting SIRT1, SIRT2, and SIRT3, demonstrating inhibitory concentrations (IC50s) of 0.54 μM, 0.253 μM, and 0.72 μM, respectively. It is utilized in cancer research [1].
价 格:¥电议型 号:T74894产 地:中国大陆
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T7489MART-1 (26-35) (human);化合物MART-1 (26-35) humanMART-1 (26-35) human;MART-1 (26-35) human
MART-1 (26-35) (human) (MART-1 (26-35) human) is a peptide fragment of MART-1 protein.
价 格:¥电议型 号:T7489产 地:中国大陆
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T74771Diaporthein B;化合物 Diaporthein BDiaporthein B
Diaporthein B, a highly oxidized pimarane diterpene, demonstrates significant activity against M. tuberculosis with a MIC of 3.1 μg/mL and exhibits IC50 values ranging from 1.5-3 μM/L against HCT 116 and LoVo colon cancer cells [1].
价 格:¥电议型 号:T74771产 地:中国大陆
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T74697Glucocorticoid receptor agonist-2;化合物 Glucocorticoid receptor agonist-2Glucocorticoid receptor agoni
Glucocorticoid receptor agonist-2 (compound 21), a glucocorticoid receptor agonist exhibiting an IC50 value of 6.6 nM, serves as an active reference for ABBV-3373 [1]. This compound is instrumental in the synthesis of anti-inflammatory ADC molecules.
价 格:¥电议型 号:T74697产 地:中国大陆
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T74678Budiodarone tartrate;化合物 Budiodarone tartrateBudiodarone tartrate
Budiodarone tartrate (ATI-2042), an analogue of Amiodarone, exhibits antiarrhythmic properties by harmoniously inhibiting multiple cardiac ion channels, including potassium, sodium, and calcium channels.
价 格:¥电议型 号:T74678产 地:中国大陆
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T74672Sirtuin modulator 5;化合物 Sirtuin modulator 5Sirtuin modulator 5
Sirtuin Modulator 5, a sirtuin modulating agent, activates SIRT1 with an efficacy marked by a DC50 value of less than 50 μM. It is applicable in enhancing cell longevity and is researched for its therapeutic potential in a wide range of diseases such as those associated with aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular diseases, blood clotting disorders, inflammation, cancer, and flushing. Furthermore, it holds promise for conditions that could benefit from boos
价 格:¥电议型 号:T74672产 地:中国大陆
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T74641Rezivertinib analogue 1;化合物 Rezivertinib analogue 1Rezivertinib analogue 1
Rezivertinib analogue 1, a process impurity of osimertinib mesylate, serves as a research tool in the study of non-small cell lung cancer (NSCLC) [1].
价 格:¥电议型 号:T74641产 地:中国大陆