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  • T2251TAE684TAE684,NVP-TAE 684,

    NVP-TAE 684 is a excellently effective and specific ALK inhibitor(IC50=3 nM).

    价 格：￥电议型 号：T2251产 地：美洲

  • T4684ML241 hydrochlorideML241 hydrochloride

    ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the chemotherapy of cancer, and provide a ra

    价 格：￥电议型 号：T4684产 地：美洲

  • T5684Ethyl 3,4-dihydroxybenzoateEthyl 3,4-dihydroxybenzoate

    Ethyl 3,4-dihydroxybenzoate(EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.

    价 格：￥电议型 号：T5684产 地：美洲

  • T8684Sotorasib；化合物AMG-510AMG-510；AMG-510

    Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib exhibits inhibitory activity against KRAS G12C mutant tumors.

    价 格：￥电议型 号：T8684产 地：中国大陆

  • T8645PF-06446846；化合物PF-06446846PF-06446846

    PF 06446846 is a potent and selective PCSK9 inhibitor

    价 格：￥电议型 号：T8645产 地：中国大陆

  • T8517Belinostat；贝利司他PX105684|||PXD101|||PXD-101；PX105684|||PXD101|||贝利司他|||PXD-101

    Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.

    价 格：￥电议型 号：T8517产 地：中国大陆

  • T83684Myelin Basic Protein Peptide (mouse, bovine) TFA；化合物 Myelin Basic Protein Peptide (mouse, bovine) TF

    Myelin basic protein (MBP) peptide, a selective substrate for protein kinase C (PKC) over protein kinase A (PKA), casein kinase 1 (CK1), CK2, phosphorylase kinase, and calcium/calmodulin-dependent protein kinase (CaMKII), is utilized to track PKC activity in primary human renal artery smooth muscle cells.

    价 格：￥电议型 号：T83684产 地：中国大陆

  • T82684Connexin mimetic peptide 40,37GAP26；化合物 Connexin mimetic peptide 40,37GAP26Connexin mimetic peptide

    Connexin mimetic peptide 40,37GAP26, a biologically active peptide, matches the GAP26 domain of the extracellular loop of major vascular connexins Cx37 and Cx40, referred to as 37,40Gap26 based on Cx homology. It has been utilized to examine gap junctions´ involvement in propagating endothelial hyperpolarizations induced by cyclopiazonic acid (CPA) in the rodent iliac artery wall. Abundant gap junction plaques comprising Cx37 and Cx40 are present in the endothelium, and the peptide exerts

    价 格：￥电议型 号：T82684产 地：中国大陆

  • T81684Neuroinflammatory-IN-1；化合物 Neuroinflammatory-IN-1Neuroinflammatory-IN-1

    Neuroinflammatory-IN-1 (Compound 5) serves as an anti-neuroinflammatory agent, exhibiting an inhibitory effect on nitric oxide (NO) production, with an IC50 of 65.4 μM [1].

    价 格：￥电议型 号：T81684产 地：中国大陆

  • T80684γ-Cadinene；化合物 γ-Cadineneγ-Cadinene

    γ-Cadinene is a naturally occurring compound identified in Tabernaemontana catharinensis [1].

    价 格：￥电议型 号：T80684产 地：中国大陆

  • T796845-HT6R antagonist 1；化合物 5-HT6R antagonist 15-HT6R antagonist 1

    Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability but also reverses MK-801-induced memory impairments in rats, suggesting its utility in Alzheimer´s disease (AD) research [1].

    价 格：￥电议型 号：T79684产 地：中国大陆

  • T78684FFN246；化合物 FFN246FFN246

    FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and emission spectra at 392/427 nm, respectively. It serves to label serotonergic neurons within mouse brain tissue via SERT-dependent accumulation [1].

    价 格：￥电议型 号：T78684产 地：中国大陆

  • T77760BMS-684；化合物BMS-684BMS-684

    BMS-684 is a selective and potent DGKα inhibitor (IC50: 15 nM) with potential antitumor activity.BMS-684 inhibits DGKα kinase, DGKβ, and DGKγ.BMS-684 activates T-cells, which may prevent and treat immune-related diseases.

    价 格：￥电议型 号：T77760产 地：中国大陆

  • T776844-(2-Aminoethyl)amino-7-chloroquinoline；N-(7-氯喹啉-4-基)乙烷-1,2-二胺N1-(7-Chloroquinolin-4-yl)ethane-1,2-d

    4-(2-Aminoethyl)amino-7-chloroquinoline (N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine) has potential anthelmintic and antitumor activity for the study of malaria.

    价 格：￥电议型 号：T77684产 地：中国大陆

  • T76849Bamlanivimab；化合物 BamlanivimabBamlanivimab

    Bamlanivimab, an Anti-Human SARS-CoV-2 monoclonal antibody (mAb), was the first of its kind to receive Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) in November 2020 for COVID-19 treatment. However, its authorization was withdrawn in April 2021 due to emerging SARS-CoV-2 variants resistant to the antibody [1].

    价 格：￥电议型 号：T76849产 地：中国大陆

  • T76848Atoltivimab；化合物 AtoltivimabAtoltivimab

    Atoltivimab (REGN3470), also known as maftivimab/odesivimab (Inmazeb), represents the first monoclonal antibody approved by the Food and Drug Administration (FDA) to combat Zaire ebolavirus (EBOV) infection [1].

    价 格：￥电议型 号：T76848产 地：中国大陆

  • T76847Imdevimab；化合物 ImdevimabImdevimab

    Imdevimab (REGN10987), a human monoclonal antibody designed to neutralize the SARS-CoV-2 virus responsible for COVID-19, demonstrates reduced efficacy against emerging COVID-19 variants. When combined with Casirivimab, it effectively reduces viral load and enhances disease management [1].

    价 格：￥电议型 号：T76847产 地：中国大陆

  • T76846Casirivimab；化合物 CasirivimabCasirivimab

    Casirivimab (REGN10933), a human monoclonal antibody targeting the SARS-CoV-2 virus responsible for COVID-19, demonstrates reduced efficacy against emerging variants. When combined with Imdevimab, it significantly lowers viral load and enhances disease outcomes [1].

    价 格：￥电议型 号：T76846产 地：中国大陆

  • T76845Sotrovimab；化合物 SotrovimabSotrovimab

    Sotrovimab (VIR 7831), a human IgG1κ pan-sarbecovirus monoclonal antibody (mAb), effectively neutralizes SARS-CoV-2, SARS-CoV-1, and various other sarbecoviruses. Developed from S309, it possesses a prolonged half-life and excellent bioavailability within the respiratory mucosa. Its mechanism potentially facilitates immune-mediated viral elimination, thereby averting the advancement of Covid-19 during the disease´s early stages [1][2].

    价 格：￥电议型 号：T76845产 地：中国大陆

  • T76844Abciximab；阿昔单抗C7E3；C7E3

    Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa, vitronectin and Mac-1 receptors.

    价 格：￥电议型 号：T76844产 地：中国大陆

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