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T76843Tebentafusp;化合物 TebentafuspTebentafusp
Tebentafusp (IMCgp100) is a bispecific fusion protein designed to target the gp100 peptide-HLA-A*02:01 complex, a melanoma-associated antigen. It directs T cells towards melanoma cells expressing gp100 through a high-affinity T-cell receptor (TCR) binding domain coupled with an anti-CD3 domain, promoting T-cell engagement. This action triggers the production of inflammatory cytokines and cytolytic proteins, culminating in the direct lysis of tumor cells [1] [2].
价 格:¥电议型 号:T76843产 地:中国大陆
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T76842Ansuvimab;化合物 AnsuvimabAnsuvimab
Ansuvimab (Ansuvimab-zyk) is a recombinant human monoclonal IgG1 antibody designed to combat Zaire ebolavirus by binding to its surface glycoprotein. This binding action inhibits the virus´s entry into host cells, effectively exhibiting antiviral activity [1].
价 格:¥电议型 号:T76842产 地:中国大陆
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T76841Enlimomab;化合物 EnlimomabEnlimomab
Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody targeting human ICAM-1, reduces leukocyte adhesion to the vascular endothelium, thus diminishing leukocyte extravasation and inflammatory tissue damage. This compound exhibits anti-inflammatory properties and is utilized in stroke research [1] [2].
价 格:¥电议型 号:T76841产 地:中国大陆
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T76840Vunakizumab;化合物 VunakizumabVunakizumab
Vunakizumab (Anti-Human IL17A Recombinant Antibody), a recombinant human IgGκ monoclonal antibody, specifically targets and inhibits IL-17A´s interaction with its receptor, making it useful for researching autoimmune conditions including psoriatic arthritis, ankylosing spondylitis, multiple sclerosis, and inflammatory arthritis [1].
价 格:¥电议型 号:T76840产 地:中国大陆
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T76795Xentuzumab;珍妥珠单抗BI 836845;BI 836845
Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits IGF1 and IGF2 growth-promoting signalling and inhibits AKT activation for the study of solid tumours.
价 格:¥电议型 号:T76795产 地:中国大陆
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T76750Cemiplimab;西米普利单抗REGN-2810|||SAR-439684;REGN-2810|||SAR-439684
Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cancer and squamous cell skin cancer research.
价 格:¥电议型 号:T76750产 地:中国大陆
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T76684Girentuximab;吉妥昔单抗cG250|||WX-G250|||G250;cG250|||WX-G250|||G250
Girentuximab (G250) is a potent anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anticancer activity for the study of uroepithelial carcinoma PET (ZiPUP).
价 格:¥电议型 号:T76684产 地:中国大陆
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T75684Monascorubrin;化合物 MonascorubrinMonascorubrin
Monascorubrin, a compound extracted from the mycelium of Monascus purpureus, exhibits significant antibiotic activity against Bacillus subtilis and Candida pseudotropicalis [1].
价 格:¥电议型 号:T75684产 地:中国大陆
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T74684Abiraterone sulfate;化合物 Abiraterone sulfateAbiraterone sulfate
Abiraterone sulfate is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .
价 格:¥电议型 号:T74684产 地:中国大陆
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T73684Preclamol hydrochloride;化合物 Preclamol hydrochloridePreclamol hydrochloride
Preclamol hydrochloride ((-)-3-PPP hydrochloride) is a selective agonist for dopamine autoreceptors with potential applications in schizophrenia research [1] [2].
价 格:¥电议型 号:T73684产 地:中国大陆
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T72684TLR7/8 agonist 7;化合物 TLR7/8 agonist 7TLR7/8 agonist 7
TLR7/8 agonist 7, a compound that functions as a TLR7/8 agonist, plays a pivotal role in activating various immune cells and is instrumental in the synthesis of immune-stimulating antibody conjugate (ISAC) molecules. This compound holds significant potential for research in immunology.
价 格:¥电议型 号:T72684产 地:中国大陆
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T70684DHPM-93;化合物 DHPM-93DHPM-93
DHPM-93 is a the most potent inhibitor of sodium iodide symporter (nis) reported to date
价 格:¥电议型 号:T70684产 地:中国大陆
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T70101EMD-66684;化合物 EMD-66684EMD-66684
EMD-66684 is a non-peptide angiotensin II receptor antagonist.
价 格:¥电议型 号:T70101产 地:中国大陆
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T6S16848-Gingerol;8-姜酚8-Gingerol
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristics. 5. 8-Gingerol seems to be effective in an animal model of rheumatoid arthritis. 6. 8-Gingerol inhibits the anti-serotonin 3 receptor function, exhibits cardiotonic activity. 7. 8-Gingerol affects gastric motility and potentially have an antispasmodic effect on the gastrointest
价 格:¥电议型 号:T6S1684产 地:中国大陆
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T68978KU-0058684;化合物 KU-0058684KU-0058684
KU-0058684 is a potent PARP and DNA-PK inhibitors.
价 格:¥电议型 号:T68978产 地:中国大陆
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T68684Piritrexim isethionate;化合物 Piritrexim isethionatePiritrexim isethionate
Piritrexim isethionate is a lipid-soluble inhibitor of dihydrofolate reductase (DHFR) that appears to be an active agent in patients with metastatic urothelial cancer when administered as a 5-day, low-dose oral schedule.
价 格:¥电议型 号:T68684产 地:中国大陆
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T68499F15845 HBr;化合物 F15845 HBrF15845 HBr
F 15845 is a blocker of the persistent sodium current prevents consequences of hypoxia in rat femoral artery. F15845 has been shown to selectively inhibit the persistent sodium current of Nav1.5[1] exerting cardioprotective effects following ischemia. In vitro testing showed minimal effects of F15845 on other important ion channels of the heart, including major Ca2+ and K+ channels.[1] This characteristic is thought to account for the limited effect of F15845 to change other heart parameters suc
价 格:¥电议型 号:T68499产 地:中国大陆
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T68498UCK2 Inhibitor-2;化合物 UCK2-IN-20874830UCK2 Inhibitor-2
UCK2 Inhibitor-2, a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2), exhibits an IC50 of 3.8 ?M and effectively suppresses uridine salvage within cells.
价 格:¥电议型 号:T68498产 地:中国大陆
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T68497FI-700;化合物 FI-700FI-700
FI-700 is a novel and potent FLT3 inhibitor with promising antileukemia activity. FI-700 showed a potent IC(50) value against FLT3 kinase at 20 nmol/L in an in vitro kinase assay. FI-700 showed selective growth inhibition against mutant FLT3-expressing leukemia cell lines and primary acute myeloid leukemia cells, whereas it did not affect the FLT3 ligand (FL)-driven growth of Wt-FLT3-expressing cells. Oral administration of FI-700 induced the regression of tumors in a s.c. tumor xenograft model
价 格:¥电议型 号:T68497产 地:中国大陆
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T68496Montelukast cyclopropaneacetamide;化合物 Montelukast cyclopropaneacetamideMontelukast cyclopropaneaceta
Montelukast cyclopropaneacetamide is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
价 格:¥电议型 号:T68496产 地:中国大陆