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T8351UBP5513,5-二羟基-2-萘酸3,5-二羟基-2-萘酸
UBP551 is a potent and selective NMDA receptors modulator.
价 格:¥电议型 号:T8351产 地:中国大陆
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T81417PP5-IN-1;PP5抑制剂1PP5-IN-1
PP5-IN-1 is a potent and competitive serine/threonine protein phosphatase-5 (PP5) inhibitor with potential anticancer activity that induces apoptosis in cancer cells.
价 格:¥电议型 号:T81417产 地:中国大陆
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T80447Pardaxin P5;化合物 Pardaxin P5Pardaxin P5
Pardaxin P5, an antimicrobial peptide, inhibits Escherichia coli at a minimum inhibitory concentration (MIC) of 13 μM [1].
价 格:¥电议型 号:T80447产 地:中国大陆
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T80384EP5-1;化合物 EP5-1EP5-1
EP5-1 is an antimicrobial peptide with antibacterial, antifungal, antitumor, and antiviral properties, notably inducing apoptosis in cancer cells and demonstrating activity against the pseudorabies virus (PRV) [1].
价 格:¥电议型 号:T80384产 地:中国大陆
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T80233p53 CBS;化合物 p53 CBSp53 Consensus binding sequence;p53 Consensus binding sequence
p53 CBS (p53 Consensus binding sequence), a biologically active peptide, functions as the p53 consensus DNA binding site.
价 格:¥电议型 号:T80233产 地:中国大陆
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T80132CBP501 Affinity Peptide;化合物 CBP501 Affinity PeptideCBP501 Affinity Peptide
CBP501 Affinity Peptide, a Chk kinase inhibitor, disrupts G2 arrest triggered by DNA-damaging agents and is utilized in cancer research [1].
价 格:¥电议型 号:T80132产 地:中国大陆
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T79877MTvkPABC-P5;化合物 MTvkPABC-P5MTvkPABC-P5
MTvkPABC-P5d, functioning as a TLR7 agonist, serves as an immune stimulant and is utilized in the synthesis of immune-stimulating antibody conjugates (ISACs) [1].
价 格:¥电议型 号:T79877产 地:中国大陆
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T79740CYP51/PD-L1-IN-3;化合物 CYP51/PD-L1-IN-3CYP51/PD-L1-IN-3
CYP51/PD-L1-IN-3 (compound L21), a quinazoline with antifungal properties, serves as a dual inhibitor targeting CYP51 (IC50: 0.205 μM) and PD-L1 (IC50: 0.039 μM). This compound promotes early fungal apoptosis within the cell cycle, diminishes intracellular concentrations of IL-2, NLRP3, and NF-κBp65 proteins, incites mitochondrial impairment and ROS accumulation, and culminates in fungal cell lysis and death [1].
价 格:¥电议型 号:T79740产 地:中国大陆
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T79739CYP51/PD-L1-IN-2;化合物 CYP51/PD-L1-IN-2CYP51/PD-L1-IN-2
CYP51/PD-L1-IN-2 (compound L20), a quinazoline with antifungal properties, is a potent dual inhibitor targeting both CYP51 (IC50: 0.263 μM) and PD-L1 (IC50: 0.017 μM). The compound promotes early apoptosis in the fungal cell cycle, markedly diminishes intracellular proteins IL-2, NLRP3, and NF-κBp65, causes mitochondrial damage and ROS build-up, culminating in fungal cell lysis and death [1].
价 格:¥电议型 号:T79739产 地:中国大陆
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T79738CYP51/PD-L1-IN-1;化合物 CYP51/PD-L1-IN-1CYP51/PD-L1-IN-1
CYP51/PD-L1-IN-1 (compound L11), a quinazoline with antifungal properties, simultaneously inhibits CYP51 (IC50: 0.884 μM) and PD-L1 (IC50: 0.083 μM). This compound prompts early apoptosis in the fungal cell cycle, markedly diminishes intracellular IL-2, NLRP3, and NF-κBp65 protein concentrations, causes mitochondrial damage and ROS accumulation, and culminates in fungal lysis and cell death [1].
价 格:¥电议型 号:T79738产 地:中国大陆
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T79408KGP591;化合物 KGP591KGP591
KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 ?M, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure and cell morphology in MDA-MB-231 cells. Additionally, it demonstrates antitumor activity in an orthotopic kidney cancer model (RENCA) [1].
价 格:¥电议型 号:T79408产 地:中国大陆
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T79184FKBP51F67V-selective antagonist Ligand2;化合物 FKBP51F67V-selective antagonist Ligand2FKBP51F67V-select
FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 or FKBP52 [1]. It effectively reverses the anxiogenic phenotype resulting from FKBP51 F67V overexpression in the amygdala.
价 格:¥电议型 号:T79184产 地:中国大陆
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T79013SLMP53-2;化合物 SLMP53-2SLMP53-2
SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with Hsp70, thereby reinstating p53´s transcriptional activity. This compound induces cell cycle arrest, apoptosis, and endoplasmic reticulum (ER) stress, displaying antitumor activity [1] [2].
价 格:¥电议型 号:T79013产 地:中国大陆
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T78902CYP51/PD-L1-IN-4;化合物 CYP51/PD-L1-IN-4CYP51/PD-L1-IN-4
CYP51/PD-L1-IN-4 (compound 14a-2) is a potent dual-target inhibitor of CYP51/PD-L1, displaying IC50 values of 0.17 and 0.021 μM, respectively. This compound demonstrates significant antifungal efficacy and combats drug-resistant fungal strains in vitro, making it a valuable agent for fungal infection research [1].
价 格:¥电议型 号:T78902产 地:中国大陆
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T76462[Glp5,Sar9] Substance P (5-11);化合物 [Glp5,Sar9] Substance P (5-11)[Glp5,Sar9] Substance P (5-11)
[Glp5,Sar9] Substance P (5-11) is an analogue of Substance P [1] .
价 格:¥电议型 号:T76462产 地:中国大陆
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T76417Yp537 TFA;化合物 Yp537 TFAYp537 TFA
Yp537 TFA is a chemical compound acting as an estrogen receptor (ER) inhibitor, specifically obstructing the dimerization process of the human estrogen receptor [1].
价 格:¥电议型 号:T76417产 地:中国大陆
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T76416Yp537;化合物 Yp537Yp537
Yp537 acts as an estrogen receptor (ER) inhibitor, specifically preventing the dimerization of the human estrogen receptor [1].
价 格:¥电议型 号:T76416产 地:中国大陆
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T76404[Glp5,(Me)Phe8,Sar9] Substance P (5-11);化合物 [Glp5,(Me)Phe8,Sar9] Substance P (5-11)[Glp5,(Me)Phe8,Sa
[Glp5,(Me)Phe8,Sar9] Substance P (5-11) (DiMe-C7) is an analogue of Substance P that acts on the neurokinin 1 receptor (NK1R) in rat brain, similarly to Substance P but with a significantly extended duration of action. This compound selectively enhances dopamine metabolism within the mesencephalon and midbrain cortex, increases motor activity, and facilitates the resumption of addictive agent-seeking behavior in rats [1] [2] [3].
价 格:¥电议型 号:T76404产 地:中国大陆
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T76403[Glp5] Substance P (5-11);化合物 [Glp5] Substance P (5-11)[Glp5] Substance P (5-11)
[Glp5] Substance P (5-11), an octapeptide, serves as a principal fragment of substance P in the rat central nervous system (CNS) and has a localized role in modulating dopamine release in the rat striatum [1].
价 格:¥电议型 号:T76403产 地:中国大陆
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T76228ASP5286;化合物 ASP5286ASP5286
ASP5286 is a novel non-immunosuppressive cyclophilin inhibitor for the research of HCV .
价 格:¥电议型 号:T76228产 地:中国大陆