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  • T76211[Asp5]-Oxytocin acetate；化合物 [Asp5]-Oxytocin acetate[Asp5]-Oxytocin acetate

    [Asp5]-Oxytocin acetate is a neurohypophyseal hormone analogue positioned at the 5-position, noted for its significant biological activity. It stimulates uterine contractions in vitro, an effect that is amplified by the presence of Mg 2+. Furthermore, this compound exhibits rat uteroconstrictor, avian vasodilator, and rat antidiuretic capabilities.

    价 格：￥电议型 号：T76211产 地：中国大陆

  • T75763TP508 TFA；化合物 TP508 TFATP508 TFA

    TP508 TFA, a 23-amino acid segment of the thrombin molecule´s receptor-binding domain, is a nonproteolytic thrombin peptide. It activates endothelial NO synthase (eNOS) to enhance nitric oxide (NO) production in human endothelial cells, thereby stimulating both endothelial cells and stem cells for tissue revascularization and regeneration [1] [2].

    价 格：￥电议型 号：T75763产 地：中国大陆

  • T74936MDM2/4-p53-IN-3；化合物 MDM2/4-p53-IN-3MDM2/4-p53-IN-3

    MDM2/4-p53-IN-3, an inhibitor of MDM2/4-p53 protein-protein interactions (PPIs), exhibits potent activity with IC50 values of 18.5 nM for MDM2-p53 and 14.8 nM for MDM4-p53. This compound is applicable in cancer research, including studies on colon cancer [1].

    价 格：￥电议型 号：T74936产 地：中国大陆

  • T74935MDM2/4-p53-IN-2；化合物 MDM2/4-p53-IN-2MDM2/4-p53-IN-2

    MDM2/4-p53-IN-2 (2q) is a potent dual inhibitor of MDM2/MDM4 and activator of p53, demonstrating IC50 values of 70.7 nM for MDM2-p53 and 81.4 nM for MDM4-p53 complexes. It facilitates cell cycle regulation, promotes apoptosis, and exhibits anticancer properties [1].

    价 格：￥电议型 号：T74935产 地：中国大陆

  • T740865-AMAM-2-CP；化合物 5-AMAM-2-CP5-AMAM-2-CP

    5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].

    价 格：￥电议型 号：T74086产 地：中国大陆

  • T73088Mavodelpar；化合物 MavodelparHPP593|||REN001|||REN001 ; HPP593；HPP593|||REN001|||REN001 ; HPP593

    Mavodelpar (REN001), a selective PPARδ agonist, effectively suppresses glomerular injury and renal fibrosis. It is utilized in the research of primary mitochondrial myopathies (PMM) and long-chain fatty acid oxidation disorders (LC-FAOD).

    价 格：￥电议型 号：T73088产 地：中国大陆

  • T7301BDP5290；化合物BDP5290BDP5290

    BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.)

    价 格：￥电议型 号：T7301产 地：中国大陆

  • T72877p53-HDM2-IN-1；化合物 p53-HDM2-IN-1p53-HDM2-IN-1

    p53-HDM2-IN-1 is a potent inhibitor of the p53-HDM2 protein-protein interaction, demonstrating an inhibitory concentration (IC 50) of 0.103 μM. This compound has significant applications in cancer research.

    价 格：￥电议型 号：T72877产 地：中国大陆

  • T72832MDM2-p53-IN-16；化合物 MDM2-p53-IN-16MDM2-p53-IN-16

    MDM2-p53-IN-16 is a potent inhibitor of the MDM2-p53 complex, exhibiting an IC 50 value of 4.3 nM for the dissociation of the human p53/MDM2 complex. It effectively reactivates p53, leading to apoptosis and cell-cycle arrest in Glioblastoma Multiforme (GBM) cells, positioning it as a valuable agent for cancer research.

    价 格：￥电议型 号：T72832产 地：中国大陆

  • T72785PRMT5:MEP50 PPI；化合物 PRMT5:MEP50 PPIPRMT5:MEP50 PPI

    PRMT5:MEP50 PPI, a pioneering inhibitor of the PRMT5:MEP50 protein-protein interaction (PRMT5:MEP50 PPI), demonstrates anti-tumor and anti-proliferative effects in lung and prostate cancer cells.

    价 格：￥电议型 号：T72785产 地：中国大陆

  • T72770p53 Activator 5；化合物 p53 Activator 5p53 Activator 5

    P53 Activator 5 is a potent activator of p53, exhibiting a SC150 value of less than 0.05 mM. It effectively binds to mutant p53, restoring its DNA-binding capability. Additionally, P53 Activator 5 demonstrates significant anti-tumor activity.

    价 格：￥电议型 号：T72770产 地：中国大陆

  • T72769p53 Activator 3；化合物 p53 Activator 3p53 Activator 3

    p53 Activator 3 is a potent activator of p53, demonstrating notable efficacy with an SC150 value of less than 0.05 mM. It effectively binds to mutant p53, reinstating its DNA-binding capability, and exhibits anti-tumor activity.

    价 格：￥电议型 号：T72769产 地：中国大陆

  • T72465Umbralisib tosylate；化合物 Umbralisib tosylateRP5264 tosylate|||TGR-1202 tosylate ; RP5264 tosylate|||

    Umbralisib Tosylate (TGR-1202) is a potent, selectively dual inhibitor targeting PI3Kδ and casein kinase-1-ε (CK1ε), demonstrating oral activity. With EC50 values of 22.2 nM and 6.0 μM for PI3Kδ and CK1ε respectively, it shows unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL). This compound is utilized in the research of hematological malignancies.

    价 格：￥电议型 号：T72465产 地：中国大陆

  • T72294S1P5 receptor agonist-1；化合物 S1P5 receptor agonist-1S1P5 receptor agonist-1

    S1P5 Receptor Agonist-1 (example 6) is a highly potent and selective agonist for the S1P5 receptor, exhibiting an EC50 value of 20 nM.

    价 格：￥电议型 号：T72294产 地：中国大陆

  • T72026p53-MDM2-IN-1；化合物p53-MDM2-IN-1p53-MDM2-IN-1

    p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 ?M. This compound holds potential for applications in anti-tumor research.

    价 格：￥电议型 号：T72026产 地：中国大陆

  • T719755-MPEP；化合物 5-MPEP5-MPEP

    5-MPEP is a neutral allosteric site ligand of the metabotropic glutamate receptor subtype 5 (mGlu5), blocking the effects of both the allosteric antagonist MPEP and potentiator CDPPB.

    价 格：￥电议型 号：T71975产 地：中国大陆

  • T70878P516-0475；化合物 P516-0475P516-0475

    P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO. This compound induces quorum sensing by stabilizing SHP pheromones in culture.

    价 格：￥电议型 号：T70878产 地：中国大陆

  • T69846VTP50469 mesylate；化合物 VTP50469 mesylateVTP50469 mesylate

    VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations.

    价 格：￥电议型 号：T69846产 地：中国大陆

  • T6925P005091；化合物P005091P5091；P5091

    P005091 (P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.

    价 格：￥电议型 号：T6925产 地：中国大陆

  • T69110Aseanostatin P5；化合物 Aseanostatin P5Aseanostatin P5

    Aseanostatin P5 inhibits myeloperoxidase (MPO) release from human polymorphonuclear leukocytes.

    价 格：￥电议型 号：T69110产 地：中国大陆

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