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T78581Selenocystine;化合物 SelenocystineSelenocystine
Selenocystine, a broad-spectrum anticancer agent, effectively induces DNA damage, notably DNA double-strand breaks (DSBs), in HepG2 cells, showcasing significant potential as a therapeutic or adjuvant agent in targeting DNA repair mechanisms for cancer treatment [1].
价 格:¥电议型 号:T78581产 地:中国大陆
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T78580Erythronic acid;化合物 Erythronic acidErythronic acid
Erythronic acid, an endogenous carbohydrate metabolite, is instrumental for research into metabolism-associated disorders. It significantly influences both the development and amelioration of hyperuricemia and is associated with mitochondrial dysfunction in cases of transaldolase deficiency [1].
价 格:¥电议型 号:T78580产 地:中国大陆
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T7858Ceftezole sodium;头孢替唑钠Celoslin|||Falomesin|||Alomen;Celoslin|||Falomesin|||头孢替唑钠|||Alomen
Ceftezole sodium (Falomesin) is a broad-spectrum cephalosporin antibiotic active gram-negative and gram-positive bacteria except for Proteus vulgaris, Pseudomonas aeruginosa, and Serratia marcescens. It has the inhibition of cell wall synthesis via affinity for penicillin-binding proteins. It also inhibits alpha-glucosidase.
价 格:¥电议型 号:T7858产 地:中国大陆
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T78558GNE-7883;化合物 GNE-7883GNE-7883
GNE-7883, a pan-TEAD inhibitor, exhibits anti-cell proliferation effects and mitigates resistance to KRAS G12C inhibitors through the inhibition of YAP/TAZ activation in various preclinical models, potentially aiding in the research of YAP/TAZ-dependent cancers [1].
价 格:¥电议型 号:T78558产 地:中国大陆
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T78557HOIPIN-1;化合物JTP0819958JTP0819958;JTP0819958
HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-kB activation.
价 格:¥电议型 号:T78557产 地:中国大陆
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T78508Delmitide acetate;化合物 Delmitide acetateRDP-58 acetate;RDP-58 acetate
Delmitide acetate (RDP58) is an orally active d-isomer decapeptide that exhibits potent anti-inflammatory properties. This compound suppresses the production of TNF-α, IFN-γ, and interleukin (IL)-12, while enhancing the activity of heme oxygenase 1. It is utilized in research related to ulcerative colitis [1] [2].
价 格:¥电议型 号:T78508产 地:中国大陆
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T7847Apelin-13 triTFA(217082-58-1(free base));人牛APELIN-13Apelin-13 triTFA(217082-58-1(free base))
Apelin-13 triTFA is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM.
价 格:¥电议型 号:T7847产 地:中国大陆
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T78458IR 813 tosylate;化合物 IR 813 tosylateIR 813 tosylate
IR 813 tosylate is a near-infrared (NIR) fluorescent dye with excitation and emission wavelengths of 815 nm and 840 nm, respectively, utilized for visualizing regional lymph nodes in mice [1].
价 格:¥电议型 号:T78458产 地:中国大陆
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T784498-Phenyl-BODIPY 505/515;化合物 8-Phenyl-BODIPY 505/5158-Phenyl-BODIPY 505/515
8-Phenyl-BODIPY 505/515, a phenyl-substituted derivative of BODIPY, serves as a fluorophore and is employed as a fluorescent probe [1] [2].
价 格:¥电议型 号:T78449产 地:中国大陆
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T78358Choline oxidase;化合物 Choline oxidaseCholine oxidase
Choline oxidase is an enzyme that facilitates the conversion of choline to glycine betaine through an intermediate, betaine aldehyde, during the synthesis of glycine betaine. Glycine betaine serves as an osmolyte. Furthermore, choline oxidase shows promise for use in the enzymatic production of betaine [1].
价 格:¥电议型 号:T78358产 地:中国大陆
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T78258Anti-Mouse CD44 Antibody (IM7);化合物 Anti-Mouse CD44 Antibody (IM7)Anti-Mouse CD44 Antibody (IM7)
The Anti-Mouse CD44 Antibody is a rat-derived IgG2b inhibitor targeting mouse CD44.
价 格:¥电议型 号:T78258产 地:中国大陆
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T78158MitoCur-1;化合物 MitoCur-1MitoCur-1
MitoCur-1, a curcumin analogue, acts as an inhibitor of mitochondrial antioxidative enzyme thioredoxin reductase 2 (TrxR2), possessing electrophilic characteristics with mitochondrial-targeting capabilities. This compound specifically induces reactive oxygen species (ROS) generation, demonstrating antitumor efficacy [1].
价 格:¥电议型 号:T78158产 地:中国大陆
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T78147TP-5801 TFA;化合物 TP-5801 TFATP-5801 TFA
TP-5801 TFA is an orally active inhibitor of TNK1, a non-receptor tyrosine kinase, with an IC50 value of 1.40 nM, demonstrating anti-tumor activity [1].
价 格:¥电议型 号:T78147产 地:中国大陆
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T78058Verazine;化合物 Verazine(-)-Verazine;(-)-Verazine
(-)-Verazine is an antifungal agent isolated from the dried roots and rhizome of Veratrum maackii Regel, which induces DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. It has applications in research related to fungal infections and neurological diseases [1] [2].
价 格:¥电议型 号:T78058产 地:中国大陆
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T77958Thalidomide-5-O-C11-NH2 hydrochloride;化合物 Thalidomide-5-O-C11-NH2 hydrochlorideThalidomide-5-O-C11-N
Thalidomide-5-O-C11-NH2 hydrochloride, a thalidomide-derived cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated to a protein ligand via a linker to synthesize PROTACs [1].
价 格:¥电议型 号:T77958产 地:中国大陆
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T77863TAM558;化合物 TAM558TAM558
TAM558 is a payload molecule utilized in the synthesis of OMTX705, which is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470, exhibiting antitumor activity [1].
价 格:¥电议型 号:T77863产 地:中国大陆
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T77858MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan;化合物 MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exate
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is an agent-linker conjugate designed for antibody-drug conjugate (ADC) applications, comprising an ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and the DNA topoisomerase I inhibitor, Exatecan. This conjugate is utilized in cancer research [1].
价 格:¥电议型 号:T77858产 地:中国大陆
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T77758AChE/BuChE-IN-4;AChE/BuChE抑制剂4AChE/BuChE-IN-4
AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with oral activity and blood-brain barrier permeability, with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.
价 格:¥电议型 号:T77758产 地:中国大陆
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T77586Eg5-IN-1;Eg5抑制剂1Eg5-IN-1
Eg5-IN-1 is a potent inhibitor of the kinesin family of motor proteins (Eg5) with an IC50 value of 1.97 ?M for Eg5.Eg5-IN-1 can be used in cancer research.
价 格:¥电议型 号:T77586产 地:中国大陆
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T77584Tubulin inhibitor 35;Tubulin抑制剂35Tubulin IN 35;Tubulin IN 35
Tubulin inhibitor 35 (Tubulin IN 35) is a potent dual inhibitor of topoisomerase I and microtubule protein polymerization with antitumor activity, inhibits migration and invasion of MGC-803 and RKO cell lines, interrupts the cell cycle and induces apoptosis.
价 格:¥电议型 号:T77584产 地:中国大陆