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T75897Orphanin FQ(1-11) TFA;化合物 Orphanin FQ(1-11) TFAOrphanin FQ(1-11) TFA
Orphanin FQ(1-11) TFA, a fragment of orphanin FQ or nociceptin (OFQ/N), acts as a powerful NOP receptor (ORL-1; OP4) agonist, exhibiting a K i of 55 nM. It lacks affinity for μ, δ, κ1, and κ3 receptors (K i >1000 nM), demonstrating its specificity. This compound displays analgesic properties in CD-1 mice [1] [2].
价 格:¥电议型 号:T75897产 地:中国大陆
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T75896[Arg14,Lys15]Nociceptin TFA;化合物 [Arg14,Lys15]Nociceptin TFA[Arg14,Lys15]Nociceptin TFA
[Arg14,Lys15]Nociceptin TFA is a potent and selective agonist for the NOP receptor (ORL1; OP4), exhibiting an EC50 of 1 nM. It demonstrates significant selectivity against opioid receptors, with IC50 values of 0.32 nM for NOP, and 280, >10000, and 1500 nM for μ, δ, and κ receptors, respectively [1].
价 格:¥电议型 号:T75896产 地:中国大陆
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T75895UFP-101 TFA;化合物 UFP-101 TFAUFP-101 TFA
UFP-101 TFA is a potent, selective, and competitive N/OFQ peptide (NOP) receptor antagonist, boasting a pK i value of 10.24 and demonstrating over 3000-fold selectivity against δ, μ, and κ opioid receptors. It exhibits antidepressant-like effects [1] [2].
价 格:¥电议型 号:T75895产 地:中国大陆
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T75894Sauvagine TFA;化合物 Sauvagine TFASauvagine TFA
Sauvagine TFA, a mammalian CRF agonist derived from a 40-amino-acid neuropeptide found in frog skin, effectively releases ACTH from rat pituitary cells. It exhibits pharmacological effects on diuresis, the cardiovascular system, and endocrine glands [1] [2] [3].
价 格:¥电议型 号:T75894产 地:中国大陆
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T75893CRF(6-33)(human) TFA;化合物 CRF(6-33)(human) TFACRF(6-33)(human) TFA
CRF(6-33)(human) TFA acts as a competitive inhibitor of the Corticotropin-Releasing Factor Binding Protein (CRF-BP), selectively interacting with CRF-BP without affecting post-synaptic Corticotropin-Releasing Factor receptors. This compound demonstrates an anti-obesity effect, as evidenced by studies [1] [2].
价 格:¥电议型 号:T75893产 地:中国大陆
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T75892Urocortin, rat TFA;化合物 Urocortin, rat TFAUrocortin, rat TFA
Urocortin (Rattus norvegicus) TFA, a neuropeptide and potent endogenous CRFR agonist, demonstrates affinity with Ki values of 13 nM for human CRF1, 1.5 nM for rat CRF2α, and 0.97 nM for mouse CRF2β, indicating its significant interaction across species.[1][2]
价 格:¥电议型 号:T75892产 地:中国大陆
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T75891α-Helical CRF(9-41) TFA;化合物 α-Helical CRF(9-41) TFAα-Helical CRF(9-41) TFA
α-Helical CRF(9-41) TFA acts as a competitive antagonist for the CRF2 receptor, possessing a binding constant (K B) of approximately 100 nM. Additionally, it serves as a partial agonist for the CRF1 receptor, exhibiting a half-maximal effective concentration (EC 50) of 140 nM [1] [2].
价 格:¥电议型 号:T75891产 地:中国大陆
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T75890Conantokin G TFA;化合物 Conantokin G TFAConantokin G TFA
Conantokin G TFA, a 17-amino-acid peptide, serves as a potent, selective, and competitive antagonist of N-Methyl-D-Aspartate (NMDA) receptors, effectively inhibiting NMDA-evoked currents in murine cortical neurons at an IC50 of 480 nM. It exhibits neuroprotective properties [1] [2].
价 格:¥电议型 号:T75890产 地:中国大陆
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T7589Afamelanotide acetate;化合物Afamelanotide acetateafamelanotide;afamelanotide
Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria.
价 格:¥电议型 号:T7589产 地:中国大陆
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T75889PKI 14-22 amide,myristoylated TFA;化合物 PKI 14-22 amide,myristoylated TFAPKI 14-22 amide,myristoylated
PKI 14-22 amide, myristoylated TFA is a potent inhibitor of cAMP-dependent protein kinase A (PKA) that diminishes IgG-mediated phagocytic response and inhibits neutrophil adhesion [1].
价 格:¥电议型 号:T75889产 地:中国大陆
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T75888PKA Inhibitor Fragment (6-22) amide TFA;PKA Inhibitor Fragment (6-22) amide三氟乙酸盐PKI-(6-22)-amide TFA
PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) is an inhibitor of the highly potent cAMP-dependent protein kinase A (PKA) inhibitor (Ki: 2.8 nM).PKA Inhibitor Fragment (6-22) amide TFA reverses the pain-relieving effects of low levels of morphine in mice.
价 格:¥电议型 号:T75888产 地:中国大陆
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T75887[Ala113]MBP(104-118) TFA;化合物 [Ala113]MBP(104-118) TFA[Ala113]MBP(104-118) TFA
[Ala113]MBP(104-118) TFA is a peptide inhibitor operating noncompetitively against protein kinase C (PKC), exhibiting inhibitory concentrations (IC50) in the range of 28-62 μM [1].
价 格:¥电议型 号:T75887产 地:中国大陆
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T75886[Ala107]MBP(104-118) TFA;化合物 [Ala107]MBP(104-118) TFA[Ala107]MBP(104-118) TFA
[Ala107]MBP(104-118) TFA is a noncompetitive peptide inhibitor of protein kinase C (PKC), exhibiting IC50 values between 46-145 μM.
价 格:¥电议型 号:T75886产 地:中国大陆
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T75885PKC β pseudosubstrate TFA;化合物 PKC β pseudosubstrate TFAPKC β pseudosubstrate TFA
PKC β pseudosubstrate TFA is a selective cell-permeable inhibitor of PKC [1] .
价 格:¥电议型 号:T75885产 地:中国大陆
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T75884ZIP TFA;化合物 ZIP TFAZIP TFA
ZIP TFA, a selective peptide inhibitor of PKMζ, is capable of blocking the impairment in morphine-conditioned place preference as induced by injections [1].
价 格:¥电议型 号:T75884产 地:中国大陆
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T75883Agitoxin-2 TFA;化合物 Agitoxin-2 TFAAgitoxin-2 TFA
Agitoxin-2 TFA, a potent inhibitor of K+ channels, exhibits IC50 values of 201 pM and 144 pM for mK V 1.3 and mK V 1.1, respectively [1] [2].
价 格:¥电议型 号:T75883产 地:中国大陆
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T75882[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA;化合物 [Lys5,MeLeu9,Nle10]-NKA(4-10) TFA[Lys5,MeLeu9,Nle10]-NKA(4-10)
[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a potent and highly selective NK2 receptor agonist, exhibiting an IC50 value of 6.1 nM [1].
价 格:¥电议型 号:T75882产 地:中国大陆
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T75881GR 64349 TFA;化合物 GR 64349 TFAGR 64349 TFA
GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, demonstrating an EC50 of 3.7 nM in rat colon. It exhibits over 1000-fold selectivity against NK1 receptors and over 300-fold selectivity against NK3 receptors, ensuring targeted action [1] [2].
价 格:¥电议型 号:T75881产 地:中国大陆
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T75880GR 94800 TFA;化合物 GR 94800 TFAGR 94800 TFA
GR 94800 TFA is a potent, selective antagonist of the NK 2 receptor peptide, demonstrating pK B values of 9.6 for NK 2, 6.4 for NK 1, and 6.0 for NK 3 receptors, respectively [1] [2].
价 格:¥电议型 号:T75880产 地:中国大陆
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T7588Lefamulin;化合物LefamulinBC-3781;BC-3781
Lefamulin (BC-3781) is a semi-synthetic compound that inhibits the synthesis of bacterial protein, which is required for bacteria to grow.
价 格:¥电议型 号:T7588产 地:中国大陆