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T75841Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA;化合物 Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFAAc-Tyr(PO3H2)-Glu-Glu-I
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) serves as a high-affinity pentapeptide that binds to the src SH2 domain with an IC 50 value of approximately 1 ?M. Additionally, it acts as an inhibitor of src SH3-SH2: phosphoprotein interactions [1].
价 格:¥电议型 号:T75841产 地:中国大陆
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T75840Hemokinin 1, human TFA;化合物 Hemokinin 1, human TFAHemokinin 1, human TFA
Hemokinin 1, human TFA acts as a selective full agonist at the tachykinin neurokinin 1 (NK1) receptor, while also being a full agonist at NK2 and NK3 receptors. It is capable of inducing opioid-independent analgesia [1] [2].
价 格:¥电议型 号:T75840产 地:中国大陆
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T7584zanubrutinib;泽布替尼BGB-3111;赞鲁替尼|||BGB-3111|||泽布替尼
Zanubrutinib (BGB-3111) is an inhibitor of Bruton tyrosine kinase (BTK).
价 格:¥电议型 号:T7584产 地:中国大陆
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T75839Kisspeptin-10, rat TFA;化合物 Kisspeptin-10, rat TFAKisspeptin-10, rat TFA
Kisspeptin-10, rat TFA serves as both a potent vasoconstrictor and an inhibitor of angiogenesis, as well as acting as a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Additionally, Kisspeptin-10 TFA demonstrates potential antioxidant properties by reducing Methotrexate-induced reproductive toxicity [1].
价 格:¥电议型 号:T75839产 地:中国大陆
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T75838PDZ1 Domain inhibitor peptide TFA;化合物 PDZ1 Domain inhibitor peptide TFAPDZ1 Domain inhibitor peptide
PDZ1 Domain Inhibitor Peptide TFA, a cyclic peptide featuring a β-Ala lactam side chain linker, specifically targets the PDZ1 domains of postsynaptic density protein 95 (PSD-95). It effectively disrupts the GluR6/PSD-95 interaction, competing against the C terminus of GluR6 for the PDZ1 domain with high efficiency [1].
价 格:¥电议型 号:T75838产 地:中国大陆
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T75837Spantide I TFA;化合物 Spantide I TFASpantide I TFA
Spantide I TFA, a selective NK1 receptor antagonist and a substance P analog, exhibits K(i) values of 230 nM for NK1 and 8150 nM for NK2 receptors, respectively. It offers a method to decrease type 1 while increasing type 2 cytokine IL-10 in the infected cornea, significantly reducing corneal perforation [1] [2] [3].
价 格:¥电议型 号:T75837产 地:中国大陆
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T75836JIP-1(153-163) TFA;化合物 JIP-1(153-163) TFAJIP-1(153-163) TFA
JIP-1(153-163) TFA (TI-JIP TFA), a c-JNK peptide inhibitor derived from residues 153-163 of the JNK-interacting protein-1 (JIP-1), exhibits modifications at Phe-11 with a C-terminal amide [1].
价 格:¥电议型 号:T75836产 地:中国大陆
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T75835HSDVHK-NH2 TFA;化合物 HSDVHK-NH2 TFAHSDVHK-NH2 TFA
HSDVHK-NH2 TFA acts as an antagonist to the αvβ3-vitronectin integrin interaction, displaying an inhibitory concentration (IC 50) of 1.74 pg/mL (2.414 pM) [1] [2].
价 格:¥电议型 号:T75835产 地:中国大陆
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T75834Antagonist G TFA;化合物 Antagonist G TFAAntagonist G TFA
Antagonist G TFA is a potent antagonist of vasopressin, with additional, weaker antagonistic effects on GRP and Bradykinin. This compound also promotes AP-1 transcription and enhances cellular sensitivity to chemotherapy [1] [2].
价 格:¥电议型 号:T75834产 地:中国大陆
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T75833HNGF6A TFA;化合物 HNGF6A TFAHNGF6A TFA
HNGF6A TFA, a humanin analogue, enhances glucose-stimulated insulin secretion and glucose metabolism, offering potential for diabetes research. It also inhibits ROS (Reactive Oxygen Species) production under oxidative stress and may prevent endothelial dysfunction and atherosclerosis in vivo [1] [2].
价 格:¥电议型 号:T75833产 地:中国大陆
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T75832Cyclotraxin B TFA;化合物 Cyclotraxin B TFACyclotraxin B TFA
Cyclotraxin B TFA, a cyclic peptide, serves as a highly potent and selective non-competitive inhibitor of TrkB, effectively impeding BDNF-triggered TrkB activity without altering BDNF binding affinity, evidenced by an IC50 of 0.30 nM. It is capable of crossing the blood-brain barrier, demonstrating analgesic and anxiolytic-like behavioral effects [1] [2] [3].
价 格:¥电议型 号:T75832产 地:中国大陆
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T75831NTR 368 TFA;化合物 NTR 368 TFANTR 368 TFA
NTR 368 TFA, a peptide derived from the p75 neurotrophin receptor (p75NTR) and corresponding to residues 368-381 of the human receptor, exhibits a helix-forming propensity in the presence of micellar lipid. It is a potent inducer of neural apoptosis [1].
价 格:¥电议型 号:T75831产 地:中国大陆
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T75830L-R4W2 TFA;化合物 L-R4W2 TFAL-R4W2 TFA
L-R4W2 TFA acts as a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), demonstrating significant inhibitory activity with an IC50 value of 0.1 μM. This compound potentially offers powerful analgesic properties [1] [2].
价 格:¥电议型 号:T75830产 地:中国大陆
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T75828[Orn5]-URP TFA;化合物 [Orn5]-URP TFA[Orn5]-URP TFA
[Orn5]-URP TFA acts as a potent and selective antagonist exclusively targeting the Urotensin-II receptor (UT), devoid of any agonist activity, and demonstrates a significant inhibitory efficiency with a pEC50 value of 7.24 [1] [2].
价 格:¥电议型 号:T75828产 地:中国大陆
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T75827UFP-803 TFA;化合物 UFP-803 TFAUFP-803 TFA
UFP-803 TFA, a potent ligand for the urotensin-II receptor (UT), exhibits minimal residual agonist activity, rendering it a valuable asset for exploring the UT system´s function in physiology and pathology [1].
价 格:¥电议型 号:T75827产 地:中国大陆
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T75826D[LEU4,LYS8]-VP TFA;化合物 D[LEU4,LYS8]-VP TFAD[LEU4,LYS8]-VP TFA
D[LEU4,LYS8]-VP TFA is a selective agonist for the vasopressin V1b receptor, demonstrating Ki values of 0.16 nM, 0.52 nM, and 1.38 nM for rat, human, and mouse V1b receptors, respectively. This compound exhibits limited antidiuretic, vasopressor, and oxytocic activities in vitro [1] [2].
价 格:¥电议型 号:T75826产 地:中国大陆
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T75825Bay 55-9837 TFA;化合物 Bay 55-9837 TFABay 55-9837 TFA
Bay 55-9837 TFA, a potent and highly selective VPAC2 agonist with a dissociation constant (Kd) of 0.65 nM, represents a potential research therapy for type 2 diabetes [1].
价 格:¥电议型 号:T75825产 地:中国大陆
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T75824Oxyntomodulin TFA;化合物 Oxyntomodulin TFAOxyntomodulin TFA
Oxyntomodulin TFA, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist [1] .
价 格:¥电议型 号:T75824产 地:中国大陆
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T75823GLP-2(rat) TFA;化合物 GLP-2(rat) TFAGLP-2(rat) TFA
GLP-2(rat) TFA, an intestinal growth factor, promotes cell proliferation and prevents apoptosis. Additionally, it increases mucosal mass and function in the residual small intestine following massive small bowel resection (MSBR), as documented in references [1] [2].
价 格:¥电议型 号:T75823产 地:中国大陆
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T75822GLP-1(9-36)amide TFA;化合物 GLP-1(9-36)amide TFAGLP-1(9-36)amide TFA
GLP-1(9-36)amide TFA, a predominant metabolite of glucagon-like peptide-1-(7-36)amide synthesized through dipeptidyl peptidase-4 (DPP-4) activity, functions as an antagonist to the human pancreatic GLP-1 receptor [1] [2].
价 格:¥电议型 号:T75822产 地:中国大陆