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T75802CTCE-9908 TFA;化合物 CTCE-9908 TFACTCE-9908 TFA
CTCE-9908 TFA, a potent and selective CXCR4 antagonist, triggers mitotic catastrophe and cytotoxicity, and suppresses migration in ovarian cancer cells expressing CXCR4 [1] [2].
价 格:¥电议型 号:T75802产 地:中国大陆
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T75801TC14012 TFA;化合物 TC14012 TFATC14012 TFA
TC14012 TFA, a serum-stable derivative of T140, is a selective peptidomimetic CXCR4 antagonist with an IC50 value of 19.3 nM. It also acts as a potent CXCR7 agonist, exhibiting an EC50 of 350 nM for recruiting β-arrestin 2 to CXCR7. This compound demonstrates anti-HIV and anti-cancer activities [1] [2].
价 格:¥电议型 号:T75801产 地:中国大陆
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T75800Ac2-26 TFA;化合物 Ac2-26 TFAAc2-26 TFA
Ac2-26 TFA, the active N-terminal peptide of Annexin A1 (AnxA1), mitigates ischemia-reperfusion-induced acute lung injury, reduces AnxA1 protein expression, and inhibits the activation of NF-κB and MAPK pathways in affected lung tissue [1].
价 格:¥电议型 号:T75800产 地:中国大陆
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T7580CX546苯并二氧六环-6-(1-哌啶基)甲酰胺苯并二氧六环-6-(1-哌啶基)甲酰胺
CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.
价 格:¥电议型 号:T7580产 地:中国大陆
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T75758TAT TFA;化合物 TAT TFATAT TFA
TAT TFA, derived from the transactivator of transcription (TAT) of human immunodeficiency virus (HIV-1), is a cell-penetrating peptide known for its ability to enhance the yields and solubility of heterologous proteins [1].
价 格:¥电议型 号:T75758产 地:中国大陆
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T75589Bitis Cornuta Venom;化合物 Bitis Cornuta VenomBitis Cornuta Venom
Bitis Cornuta (Many-horned Adder) Venom, sourced from Bitis Cornuta, comprises snake venom phospholipase A2 (sPLA2) toxins that exhibit anticoagulant properties by inhibiting the prothrombinase complex, consequently promoting clot formation through the conversion of prothrombin to thrombin [1].
价 格:¥电议型 号:T75589产 地:中国大陆
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T75588Bitis Armata Venom;化合物 Bitis Armata VenomBitis Armata Venom
Bitis Armata Venom (Southern Adder Venom), derived from the Bitis genus of Viperid snakes, exhibits neurotoxic activity via nAChR mimotope binding [1].
价 格:¥电议型 号:T75588产 地:中国大陆
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T75587Dendroaspis Viridis Venom;化合物 Dendroaspis Viridis VenomDendroaspis Viridis Venom
Dendroaspis viridis venom (Western Green Mamba Venom) is derived from Dendroaspis viridis (western green mamba) and can isolate various subtypes of muscarinic toxins that target different mAChR subtypes. This venom is a complex blend of small molecules, peptides, and proteins with neurotoxic, cytotoxic, cardiotoxic, musculotoxic activities, and possesses enzyme actions. Research has demonstrated that it also has antitumor, antibacterial, anticoagulant, and analgesic properties [1] [2].
价 格:¥电议型 号:T75587产 地:中国大陆
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T75586Dendraspis Angusticeps Venom;化合物 Dendraspis Angusticeps VenomDendraspis Angusticeps Venom
Dendraspis Angusticeps Venom (Eastern Green Mamba Venom), extracted from the green mamba (Dendraspis Angusticeps), comprises natriuretic peptides and fasciculins (anticholinesterase toxins). This venom promotes the release of acetylcholine and prevents quinuclidinyl benzilate from binding to mAChR [1] [2] [3] [4].
价 格:¥电议型 号:T75586产 地:中国大陆
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T75585Naja Mossambica Venom;化合物 Naja Mossambica VenomNaja Mossambica Venom
Naja Mossambica Venom (Mozambique Spitting Cobra Venom) is a snake venom derived from Naja Mossambica, exhibiting antifungal activity against Candida species. Additionally, extracts from Naja Mossambica Venom, including phospholipase A2, can inhibit the activity of sodium-potassium ATPases [1] [2].
价 格:¥电议型 号:T75585产 地:中国大陆
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T75584Naja Pallida Venom;化合物 Naja Pallida VenomNaja Pallida Venom
Naja Pallida Venom (Red Spitting Cobra Venom) is derived from the Naja Pallida and exhibits both antifungal and anticoagulant properties, specifically against Candida species. This venom comprises cytotoxin and cardiotoxin components, demonstrating its multifaceted biochemical activities [1] [2] [3].
价 格:¥电议型 号:T75584产 地:中国大陆
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T75583Naja Ashei Venom;化合物 Naja Ashei VenomNaja Ashei Venom
Naja Ashei Venom, also known as Ashe´s Spitting Cobra Venom, is a toxin derived from Naja Ashei. This venom triggers mitochondria-mediated apoptosis in human colorectal cancer cells and possesses a protein fraction with antimicrobial activity [1] [2].
价 格:¥电议型 号:T75583产 地:中国大陆
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T75582Naja Melanoleuca Venom;化合物 Naja Melanoleuca VenomNaja Melanoleuca Venom
Naja Melanoleuca Venom (Forest Cobra Venom) is a snake venom derived from Naja Melanoleuca, exhibiting hemolytic activity against human erythrocytes. It contains α-neurotoxins that isolate from the venom and inhibit the GABAA receptor [1] [2].
价 格:¥电议型 号:T75582产 地:中国大陆
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T75581Naja Oxiana Venom;化合物 Naja Oxiana VenomNaja Oxiana Venom
Naja Oxiana Venom (Caspian Cobra Venom), extracted from Naja Oxiana, has the capacity to induce apoptosis in cancer cells with minimal impact on healthy cells. It contains cytotoxins CTI and CTII, which disrupt the cell membrane [1] [2].
价 格:¥电议型 号:T75581产 地:中国大陆
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T755805-Cholestene-26-oic acid-3β-ol;化合物 5-Cholestene-26-oic acid-3β-ol5-Cholestene-26-oic acid-3β-ol
5-Cholestene-26-oic acid-3β-ol is a cholesterol catabolite [1] .
价 格:¥电议型 号:T75580产 地:中国大陆
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T7558CID-1067700化合物CID-10677002-[[(苯甲酰基氨基)硫代甲酰]氨基]-4,7-二氢-5,5-二甲基-5H-噻吩并[2,3-C]吡喃-3-羧酸
CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).
价 格:¥电议型 号:T7558产 地:中国大陆
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T75558Bruceine J;化合物 Bruceine JBruceine J
Bruceine J, a quassinoid naturally derived from the fruits of Br. javanica, exhibits anti-Babesial activity [1].
价 格:¥电议型 号:T75558产 地:中国大陆
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T75458(-)-10,11-Dihydroxyfarnesol;化合物 (-)-10,11-Dihydroxyfarnesol(-)-10,11-Dihydroxyfarnesol
(-)-10,11-Dihydroxyfarnesol, isolated from the endolichenic fungus Cryptomarasmius aucubae, significantly inhibits nitric oxide (NO) production [1].
价 格:¥电议型 号:T75458产 地:中国大陆
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T75374BDP 581/591 NHS ester;化合物 BDP 581/591 NHS esterBDP 581/591 NHS ester
BDP 581/591 NHS ester, a borondipyrromethene dye (Ex=585 nm, Em=594 nm), exhibits a relatively long fluorescence lifetime and significant two-photon excitation cross-section. This compound is applicable in fluorescence polarization analysis, interacts with reactive oxygen species (ROS) to modify fluorescence, and, as an NHS ester derivative, binds to the primary and secondary amine groups of proteins, peptides, and various molecules. Storage instructions highlight the importance of protecting it
价 格:¥电议型 号:T75374产 地:中国大陆
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T75258MM-401 TFA;化合物 MM-401 TFAMM-401 TFA
MM-401 (TFA), an MLL1 H3K4 methyltransferase inhibitor, effectively impedes MLL1 activity (IC 50 = 0.32 ?M) by preventing MLL1-WDR5 interaction. It can induce cell cycle arrest, apoptosis, and differentiation, offering potential for MLL leukemia research [1].
价 格:¥电议型 号:T75258产 地:中国大陆