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T74397nAChR modulator-2；化合物 nAChR modulator-2nAChR modulator-2
nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .
价 格：￥电议型 号：T74397产 地：中国大陆
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T74396nAChR modulator-1；化合物 nAChR modulator-1nAChR modulator-1
nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .
价 格：￥电议型 号：T74396产 地：中国大陆
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T74158Aβ Fibrillization modulator 1；化合物 Aβ Fibrillization modulator 1Aβ Fibrillization modulator 1
Aβ Fibrillization Modulator 1 stabilizes amyloid-beta (Aβ) monomers, preventing their aggregation into fibrils.
价 格：￥电议型 号：T74158产 地：中国大陆
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T72774Ras modulator-1；化合物 Ras modulator-1Ras modulator-1
Ras modulator-1 is a modulator of Ras.
价 格：￥电议型 号：T72774产 地：中国大陆
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T72661A1AT modulator 2；化合物 A1AT modulator 2A1AT modulator 2
A1AT Modulator 2, an α-1 antitrypsin (A1AT) modulator, exhibits an IC50 value greater than 1.0 μM and an EC50 value less than 0.4 μM. It is utilized in the study of infection and inflammation.
价 格：￥电议型 号：T72661产 地：中国大陆
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T72615STING modulator-4；化合物 STING modulator-4STING modulator-4
STING Modulator-4 is a competitive modulator of STING, exhibiting a K_i value of 0.0933 μM for the R232H STING variant. It demonstrates an EC_50 of over 10 μM for p-IRF3 activation in THP-1 cells.
价 格：￥电议型 号：T72615产 地：中国大陆
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T72614STING modulator-3；化合物 STING modulator-3STING modulator-3
STING modulator-3 is a STING inhibitor that effectively inhibits R232 STING, exhibiting a Ki value of 43.1 nM in scintillation proximity assays. Despite its inhibitory action on R232 STING, it does not affect IRF-3 activation or TNF-β induction in THP-1 cells.
价 格：￥电议型 号：T72614产 地：中国大陆
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T72598IL-17 modulator 5；化合物 IL-17 modulator 5IL-17 modulator 5
IL-17 modulator 5 is a IL-17 inhibitor, with an IC 50 of 1 nM [1] .
价 格：￥电议型 号：T72598产 地：中国大陆
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T72596RORγt modulator 5；化合物 RORγt modulator 5RORγt modulator 5
RORγt modulator 5, a potent RORγt modulator, exhibits a dissociation constant (K_i) of <100 nM. This compound holds promise for the treatment of diseases mediated by RORγ, including inflammatory, metabolic, and autoimmune disorders.
价 格：￥电议型 号：T72596产 地：中国大陆
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T72549IL-17A modulator-3；化合物 IL-17A modulator-3IL-17A modulator-3
IL-17A Modulator-3, an inhibitor of IL-17A/A, exhibits an IC 50 value of less than 10 μM. It is utilized in research related to inflammation, cancer, and autoimmune diseases.
价 格：￥电议型 号：T72549产 地：中国大陆
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T72483Sirtuin modulator 4；化合物 Sirtuin modulator 4Sirtuin modulator 4
Sirtuin Modulator 4, a sirtuin modulator, exhibits an inhibitory effect on SIRT1, presenting an EC 50 value ranging from 51-100 μM. It is potentially useful in research aimed at prolonging cell lifespan and preventing a broad spectrum of diseases and disorders such as diabetes, obesity, neurodegenerative, cardiovascular diseases, inflammation, and cancer.
价 格：￥电议型 号：T72483产 地：中国大陆
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T72417AChE/Nrf2 modulator 1；化合物 AChE/Nrf2 modulator 1AChE/Nrf2 modulator 1
AChE/Nrf2 modulator 1, an orally active compound, serves as a modulator of acetylcholinesterase (AChE) and nuclear factor erythroid 2-related factor 2 (Nrf2). It exhibits Nrf2 inductive activity alongside inhibitory effects on eeAChE and hAChE, demonstrating IC 50 values of 0.07 μM and 0.38 μM, respectively. This compound is applicable in Alzheimer´s disease research.
价 格：￥电议型 号：T72417产 地：中国大陆
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T72102Glucocorticoid receptor modulator 1；化合物 Glucocorticoid receptor modulator 1Glucocorticoid receptor m
Glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting IC50 values of 9 nM and 130 nM against NF-κB and AP-1, respectively. It effectively reduces the expression of inflammatory factors such as IL-6, IL-1β, and TNF-α, and alleviates dermatitis in mice.
价 格：￥电议型 号：T72102产 地：中国大陆
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T67896CB2R/FAAHu00A0modulator-1；CB2R/FAAH调节剂-1CB2R/FAAHu00A0modulator-1
CB2R/FAAH?modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the production of pro-inflammatory and anti-inflammatory cytokines and is commonly used in inflammation studies. The Kis for CB2R and CB1R are 14.8 nM and 241.3 nM, respectively.
价 格：￥电议型 号：T67896产 地：中国大陆
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T67884β-catenin modulator IIa-661；化合物 β-catenin modulator IIa-661β-catenin modulator IIa-661
β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.
价 格：￥电议型 号：T67884产 地：中国大陆
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T67832ALDH2 modulator 1；ALDH2调节剂1ALDH2 modulator 1
ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.
价 格：￥电议型 号：T67832产 地：中国大陆
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T67747CB2R/FAAH modulator-3；化合物CB2R/FAAH modulator-3CB2R/FAAH modulator-3
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 3.4 μM. CB2R/FAAH modulator-3 has research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
价 格：￥电议型 号：T67747产 地：中国大陆
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T67745CB2R/FAAHu00A0modulator-2；化合物CB2R/FAAHu00A0modulator-2CB2R/FAAHu00A0modulator-2
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 has studies research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
价 格：￥电议型 号：T67745产 地：中国大陆
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T67742EX-A5386；肾上腺糖皮质激素受体调节剂1Glucocorticoid receptor modulator-1；Glucocorticoid receptor modulator-1
EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM.
价 格：￥电议型 号：T67742产 地：中国大陆
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T6679SRT 2104；化合物SRT2104SRT2104|||sirtuin modulator|||GSK2245840；SRT2104|||sirtuin modulator|||GSK2245840
SRT 2104 (GSK2245840) is a selective and brain-permeable SIRT1 activator.
价 格：￥电议型 号：T6679产 地：中国大陆
