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T6084Rabusertib;化合物RabusertibLY2603618|||IC-83;LY2603618|||IC-83
Rabusertib (IC-83) is an inhibitor of the cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiating activity. Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non-Small Cell Lung Cancer.
价 格:¥电议型 号:T6084产 地:中国大陆
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T60763MMG-11 quarterhydrate;化合物 MMG-11 quarterhydrateMMG-11 quarterhydrate
MMG-11 quarterhydrate is a potent and selective antagonist of human TLR2 which inhibits both TLR2/1 and TLR2/6 signaling with low cytotoxicity. The IC 50 s of MMG-11 quarterhydrate for Pam 3 CSK 4 -induced hTLR2/1 and for Pam 2 CSK 4 -induced hTLR2/6 responses is 1.7 μM and 5.7 μM, respectively[1].
价 格:¥电议型 号:T60763产 地:中国大陆
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T60705Flupirtine;化合物 FlupirtineFlupirtine
Flupirtine(D 9998) is a selective neuronal potassium channel opener as well as shows properties of NMDA receptor antagonist.
价 格:¥电议型 号:T60705产 地:中国大陆
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T6070(E/Z)-Rigosertib sodium;(E/Z)-Rigosertib 钠盐(E/Z) ON-01910 sodium;N-[2-甲氧基-5-[[[2-(2,4,6-三甲氧基苯基)乙烯基]磺
ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells.It is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity.
价 格:¥电议型 号:T6070产 地:中国大陆
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T60631SIRT1-IN-3;化合物 SIRT1-IN-3SIRT1-IN-3
SIRT1-IN-3 (compound 3j) is a potent and selective inhibitor of silent information regulator 1 (SIRT1) with an IC 50 of 4.2 μM [1].
价 格:¥电议型 号:T60631产 地:中国大陆
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T60613Mab Aspartate Decarboxylase-IN-1;化合物 Mab?Aspartate Decarboxylase-IN-1Mab Aspartate Decarboxylase-IN-
Mab Aspartate Decarboxylase-IN-1 is a potent inhibitor of aspartate decarboxylase (PanD) (IC50 = 56.3 μM) with antibacterial activity [1].
价 格:¥电议型 号:T60613产 地:中国大陆
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T6051Orteronel化合物(S)-OrteronelTAK-700|||(S)-Orteronel
Orteronel ((S)-Orteronel)(TAK-700) was selected as a candidate for clinical evaluation. orteronel (TAK-700) is currently in phase III clinical trials for the treatment of castration-resistant prostate cancer.
价 格:¥电议型 号:T6051产 地:中国大陆
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T6050TAK-700;化合物(S/R)-Orteronel(S/R)-Orteronel|||Orteronel;(S/R)-Orteronel|||Orteronel
TAK-700 (Orteronel) (Orteronel) is a potent and highly selective human 17, 20-lyase inhibitor with IC50 of 38 nM, exhibits >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). Phase 3.
价 格:¥电议型 号:T6050产 地:中国大陆
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T60410ART-IN-1;化合物 ART-IN-1ART-IN-1
ART-IN-1 (compound 7) is a selective inhibitor of PARP with IC 50 s of 19, 22, 2.4, >100, 1.1 μM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively [1].
价 格:¥电议型 号:T60410产 地:中国大陆
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T60373SIRT1-IN-2;化合物 SIRT1-IN-2SIRT1-IN-2
SIRT1-IN-2 (compound 3h) is a potent and selective inhibitor of SIRT1 (silent information regulator 1) with an IC 50 of 1.6 μM [1].
价 格:¥电议型 号:T60373产 地:中国大陆
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T60257SIRT-IN-3;化合物 SIRT-IN-3SIRT-IN-3
SIRT-IN-3, a potent inhibitor of SIRT1 with an IC50 value of 17 μM, exhibits approximate 4-fold and 14-fold greater selectivity for SIRT1 over SIRT2 and SIRT3, with respective IC50 values of 74 μM for SIRT2 and 235 μM for SIRT3 [1].
价 格:¥电议型 号:T60257产 地:中国大陆
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T6019Volasertib;伏拉塞替BI 6727;BI 6727|||伏拉塞替
Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis. It also inhibits PLK2/PLK3 (IC50s: 5/56 nM).
价 格:¥电议型 号:T6019产 地:中国大陆
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T60163Lurtotecan;勒托替康GI147211|||OSI-211;GI147211|||OSI-211
Lurtotecan (GI147211) is a semisynthetic Camptothecin analog. Lurtotecan is a topoisomerase I inhibitor with anticancer effects.
价 格:¥电议型 号:T60163产 地:中国大陆
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T5S2254Swertianolin;当药醇苷Bellidifolin-8-O-Glucoside;Bellidifolin-8-O-Glucoside|||当药醇苷
1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin and swertiamarin show significant hepatoprotective effect in the liver damage model induced by alpha-naphthylisot hiocyanate. 3. Swertianolin shows anti-acetylcholinesterase activity effects. 4. Swertianolin shows that it can scavenge superoxide and hydroxyl radicals with the st
价 格:¥电议型 号:T5S2254产 地:中国大陆
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T5964Olmesartan;奥美沙坦CS 088|||RNH 6270;CS 088|||奥美沙坦|||RNH 6270
Olmesartan (RNH 6270) is an Angiotensin II Type I receptor antagonist. Olmesartan is the active form of the antihypertensive drug olmesartan medoxomil,and has antihypertensive activity.
价 格:¥电议型 号:T5964产 地:中国大陆
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T5858Sertindole;舍吲哚Lu 23-174;Lu 23-174|||舍吲哚
Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, respectively)
价 格:¥电议型 号:T5858产 地:中国大陆
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T5818Rigosertib sodium;化合物RigosertibRigosertib|||Estybon|||ON-01910;Rigosertib|||Estybon|||ON-01910
Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.
价 格:¥电议型 号:T5818产 地:中国大陆
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T5803D(-)-Tartaric acid;酒石酸D(-)-Tartaric acid
D(-)-Tartaric acid found in many plants, particularly tamarinds and grapes,it is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administration. Carbon dioxide extends the stomach and provides a negative contrast medium during double contrast radiography.
价 格:¥电议型 号:T5803产 地:中国大陆
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T5675Almonertinib hydrochloride;盐酸阿美替尼HS-10296 hydrochloride;HS-10296 hydrochloride|||盐酸阿美替尼
Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.
价 格:¥电议型 号:T5675产 地:中国大陆
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T56502,2’:5’,2’’-Terthiophene;alpha-三联噻吩α-Terthienyl|||Trithiophene;alpha-三联噻吩|||α-Terthienyl|||Trithioph
2,2´:5´,2´´-Terthiophene (Trithiophene) (α-Terthiophene) is an oligomer of the heterocycle thiophene. α-Terthiophene has been employed as building block for the organic semi-conductor polythiophene.
价 格:¥电议型 号:T5650产 地:中国大陆