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T40697Glucocorticoids receptor agonist 2；Glucocorticoids receptor agonist 2Glucocorticoids receptor agonis
Glucocorticoid receptor agonist 2 is a highly effective anti-inflammatory compound, derived from arylpyrazole, that actively binds to and activates the glucocorticoid receptor. This compound exhibits potent anti-inflammatory properties without disrupting insulin secretion.
价 格：￥电议型 号：T40697产 地：中国大陆
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T40629Norswertianolin；NorswertianolinNorswertianolin
Norswertianolin, a compound isolated from G. acuta, functions as a CSE activator and shows promise as a potential cardiovascular therapeutic.
价 格：￥电议型 号：T40629产 地：中国大陆
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T40606Tetraethylene glycol monohexadecyl ether；Tetraethylene glycol monohexadecyl etherTetraethylene glyco
Tetraethylene glycol monohexadecyl ether, a PEG-based PROTAC linker, is suitable for synthesizing PROTACs.
价 格：￥电议型 号：T40606产 地：中国大陆
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T40254MRTX-1719；化合物MRTX-1719MRTX-1719
MRTX-1719 is a potent, first-in-class, selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.
价 格：￥电议型 号：T40254产 地：中国大陆
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T40236ART812；化合物ART812ART812；ART812
ART812 is an orally active inhibitor of DNA polymerase Polθ, possessing an IC50 value of 7.6 nM. Additionally, ART812 exhibits a cell-based microhomology-mediated end joining (MMEJ) IC50 value of 240 nM.
价 格：￥电议型 号：T40236产 地：中国大陆
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T40190MRTX849 ethoxypropanoic acid；MRTX849 ethoxypropanoic acidMRTX849 ethoxypropanoic acid
MRTX849 ethoxypropanoic acid is a compound that contains a ligand for KRAS G12C and a PROTAC linker. It is commonly employed in the synthesis of PROTAC LC-2, which is a highly effective and innovative PROTAC. LC-2 has been proven to degrade endogenous KRAS G12C with remarkable potency, exhibiting DC50 values ranging from 0.25 to 0.76 μM.
价 格：￥电议型 号：T40190产 地：中国大陆
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T4019Cambinol；化合物CambinolSIRT1/2 Inhibitor IV|||NSC 112546；SIRT1/2 Inhibitor IV|||NSC 112546
Cambinol (SIRT1/2 Inhibitor IV) is a cell-permeable b-naphthol compound that inhibits the NAD-dependent deacetylase activity of SIRT1/2 (IC50: 56/59 μM, respectively) in a substrate-, but not NAD-, competitive manner. Cambinol inhibits SIRT5 deacetylase activity only at much higher concentrations (IC50 >300 μM) and no inhibitory for the class I and II HDACs. In BCL6-expressing Burkitt lymphoma cell lines, Cambinol-induced apoptosis has been attributed to the hyperacetylation of p53 and BCL6.Camb
价 格：￥电议型 号：T4019产 地：中国大陆
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T40189MRTX849 acid；MRTX849 acidMRTX849 acid；MRTX849 acid
MRTX849 acid, a derivative of MRTX849, is employed in the synthesis of PROTAC LC-2. LC-2, a potent and pioneering PROTAC, exhibits the ability to efficiently degrade endogenous KRAS G12C with DC50 values ranging between 0.25 and 0.76 μM.
价 格：￥电议型 号：T40189产 地：中国大陆
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T40156MRTX849 analog 24；MRTX849 analog 24MRTX849 analog 24；MRTX849 analog 24
MRTX849 analog 24 is an alkyne-containing click probe analogue of the MRTX849 inhibitor for KRAS G12C. It is specifically designed for studying the functionality of MRTX849.
价 格：￥电议型 号：T40156产 地：中国大陆
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T40059Nicotinamide riboside tartrate；烟酰胺核糖酒石酸盐Nicotinamide riboside tartrate
Nicotinamide riboside tartrate (NRT) is an oral NAD+ precursor that raises NAD+ levels, activates SIRT1 and SIRT3, and serves as a vitamin B3 (niacin) source. NRT also improves oxidative metabolism and protects against metabolic abnormalities induced by a high-fat diet. Furthermore, NRT mitigates cognitive decline in a transgenic mouse model of Alzheimer´s disease.
价 格：￥电议型 号：T40059产 地：中国大陆
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T3S1447Arteannuin B；青蒿素BArteannuin B
1. Arteannuin B has potent antimalarial activity.
价 格：￥电议型 号：T3S1447产 地：中国大陆
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T3999118-Oxocortisol；18-Oxocortisol18-Oxocortisol
18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling.
价 格：￥电议型 号：T39991产 地：中国大陆
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T3995Amcasertib；安卡舍替BBI503；安卡舍替|||BBI503
Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.
价 格：￥电议型 号：T3995产 地：中国大陆
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T39818Desmorpholinyl Quizartinib-PEG2-COOHDesmorpholinyl Quizartinib-PEG2-COOHDesmorpholinyl Quizartinib-P
Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal tandem duplication (ITD) through PROTAC technology. The degrader exhibits an IC50 of 0.6 nM.
价 格：￥电议型 号：T39818产 地：中国大陆
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T39608Cirtuvivint化合物CirtuvivintSM08502
Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.
价 格：￥电议型 号：T39608产 地：中国大陆
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T39520Vamifeport；化合物 VamifeportVIT-2763；VIT-2763
Vamifeport (VIT-2763) is a novel orally active inhibitor that targets iron transport proteins and reduces markers of hemolysis in the SCD Townes model.VIT-2763 improves anemia and erythropoiesis, ameliorates vascular inflammation, and can be studied in β-thalassemia.
价 格：￥电议型 号：T39520产 地：中国大陆
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T39513Ladostigil hemitartrate；Ladostigil hemitartrateTV-3326 hemitartrate|||Ladostigil hemitartrate；TV-332
Ladostigil hemitartrate (TV-3326) is a compound that acts as a dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO). It has IC50 values of 37.1 μM for MAO-B and 31.8 μM for AChE. In addition, Ladostigil hemitartrate possesses neuroprotective, antioxidant, and anti-inflammatory properties. It is commonly used in research relating to depression and Alzheimer´s disease.
价 格：￥电议型 号：T39513产 地：中国大陆
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T39466TilpisertibTilpisertibGS-4875
Tilpisertib is a serine/threonine kinase inhibitor (WO2017007689).
价 格：￥电议型 号：T39466产 地：中国大陆
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T39275Befotertinib；化合物BefotertinibD-0316|||Befotertinib；D-0316|||Befotertinib
Befotertinib (D-0316) is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cell lung cancer.
价 格：￥电议型 号：T39275产 地：中国大陆
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T39260Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH；Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OHFmoc-Gln(Trt)-Ser(psi(Me,Me)p
Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH is a dipeptide.
价 格：￥电议型 号：T39260产 地：中国大陆
