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T39233SIRT7 inhibitor 97491；化合物SIRT7 inhibitor 97491SIRT7 inhibitor 97491
SIRT7 inhibitor 97491 is an HDAC inhibitor with high specificity for SIRT7 (IC50 = 325 nM). SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.
价 格：￥电议型 号：T39233产 地：中国大陆
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T39104ItacnosertibItacnosertibItacnosertib|||TP-0184
Itacnosertib (TP-0184) is a chemical compound that acts as an inhibitor of JAK2, ACVR1 (ALK2), and ALK5, as indicated in WO2014151871.
价 格：￥电议型 号：T39104产 地：中国大陆
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T39090Uzansertib；UzansertibINCB053914；INCB053914
Uzansertib (INCB053914) is a potent ATP-competitive pan-PIM kinase inhibitor. It exhibits exceptional inhibitory activity against PIM1, PIM2, and PIM3 with IC50 values of 0.24 nM, 30 nM, and 0.12 nM, respectively. Furthermore, Uzansertib demonstrates significant anti-proliferative effects against an assorted range of hematologic tumor cell lines.
价 格：￥电议型 号：T39090产 地：中国大陆
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T39045Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH；Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OHFmoc-Gln(Trt)-Thr(psi(Me,Me)p
Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH is a dipeptide.
价 格：￥电议型 号：T39045产 地：中国大陆
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T39031Olmesartan impurity；Olmesartan impurityOlmesartan impurity
Olmesartan impurity, a compound related to Olmesartan, is an angiotensin II receptor (AT1R) antagonist utilized in the study of high blood pressure. Olmesartan (RNH-6270) is the parent compound with similar properties and functions as an AT1R antagonist.
价 格：￥电议型 号：T39031产 地：中国大陆
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T39010Xanomeline tartrateXanomeline tartrateLY 246708 tartrate|||Xanomeline tartrate
Xanomeline (LY 246708), a potent agonist of muscarinic M1/M4 receptors, exhibits antipsychotic-like activity and enhances neuronal excitability. It is a valuable compound for studying schizophrenia.
价 格：￥电议型 号：T39010产 地：中国大陆
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T38983Dazucorilant；DazucorilantCORT113176；CORT113176
Dazucorilant (CORT113176) is a non-steroidal glucocorticoid receptor (GR) modulator characterized by its high affinity and selectivity. With an impressive K i value of ＜1 nM in vitro, Dazucorilant proves to be an exceptional compound for investigating neurological disorders.
价 格：￥电议型 号：T38983产 地：中国大陆
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T38913Furaltadone L-tartrate；Furaltadone L-tartrateFuraltadone L-tartrate|||Altafur L-tartrate；Furaltadone
Furaltadone L-tartrate (Altafur L-tartrate), a nitrofuran antimicrobial agent, is potentially useful for researching Salmonella enteritidis infections in chickens. It demonstrates both inhibitory and bactericidal properties against Staphylococci in vitro.
价 格：￥电议型 号：T38913产 地：中国大陆
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T38847VevorisertibVevorisertibVevorisertib|||ARQ 751
Vevorisertib (ARQ 751) is a highly effective oral compound that selectively inhibits pan-AKT serine/threonine kinases such as AKT1 (with an IC50 value of 0.55 nM), AKT2 (with an IC50 value of 0.81 nM), and AKT3 (with an IC50 value of 1.31 nM). This compound, either as a standalone treatment option or in combination with other anti-cancer agents, is ideally suited for conducting research on solid tumors characterized by PIK3CA/AKT/PTEN mutations[4].
价 格：￥电议型 号：T38847产 地：中国大陆
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T38846Vevorisertib trihydrochloride；化合物Vevorisertib trihydrochlorideARQ 751 trihydrochloride；ARQ 751 trihy
Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is a selective and potent inhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3. Vevorisertib trihydrochloride is used in the study of hepatocellular carcinoma and advanced solid tumours.
价 格：￥电议型 号：T38846产 地：中国大陆
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T38821Thiol-PEG2-t-butyl ester；Thiol-PEG2-t-butyl esterThiol-PEG2-t-butyl ester；Thiol-PEG2-t-butyl ester
Thiol-PEG2-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T38821产 地：中国大陆
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T38778DB2115 tertahydrochloride；DB2115 tertahydrochlorideDB2115 tertahydrochloride；DB2115 tertahydrochlori
DB2115 (tertahydrochloride) is a powerful inhibitor of the myeloid master regulator PU.1. With significant potential in cancer research, particularly hematologic cancers like leukemia, as well as other conditions linked to PU.1 dysfunction, DB2115 (tertahydrochloride) offers promising avenues of study.
价 格：￥电议型 号：T38778产 地：中国大陆
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T38767MRT-83 hydrochloride；MRT-83 hydrochlorideMRT-83 hydrochloride
MRT-83 (hydrochloride) is a potent antagonist of the Smoothened (Smo) receptor, effectively inhibiting the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. With its potential applications in the study of cancer disease, MRT-83 (hydrochloride) demonstrates promising prospects for research purposes.
价 格：￥电议型 号：T38767产 地：中国大陆
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T38723β-Aminoarteether；化合物β-Aminoarteetherβ-Aminoarteether|||SM934 free base；β-Aminoarteether|||SM934 free
β-Aminoarteether (SM934 free base), an orally active derivative of Artemisinin, serves a pivotal role in the research of inflammation and autoimmune disorders, including those related to lupus diseases.
价 格：￥电议型 号：T38723产 地：中国大陆
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T38620Prexasertib dimesylate；Prexasertib dimesylateLY2606368 dimesylate；LY2606368 dimesylate
Prexasertib dimesylate (LY2606368 dimesylate) is a highly selective ATP-competitive second-generation inhibitor of checkpoint kinase 1 (CHK1). With a K i of 0.9 nM and an IC 50 of <1 nM, Prexasertib dimesylate effectively inhibits CHK2 (IC 50 = 8 nM) and RSK1 (IC 50 = 9 nM). Its mechanism of action involves inducing double-stranded DNA breakage and replication catastrophe, ultimately leading to apoptosis. Moreover, Prexasertib dimesylate demonstrates potent anti-tumor activity.
价 格：￥电议型 号：T38620产 地：中国大陆
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T38574Trt-PEG4-C2-acid hydrate；Trt-PEG4-C2-acid hydrateTrt-PEG4-C2-acid hydrate；Trt-PEG4-C2-acid hydrate
Trt-PEG4-C2-acid (hydrate) is a polyethylene glycol (PEG)-derived linking moiety, specifically designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs).
价 格：￥电议型 号：T38574产 地：中国大陆
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T38501Fmoc-Phe-Lys(Trt)-PAB；Fmoc-Phe-Lys(Trt)-PABFmoc-Phe-Lys(Trt)-PAB
Fmoc-Phe-Lys(Trt)-PAB is a cleavable linker for antibody-drug conjugates (ADCs) synthesis.
价 格：￥电议型 号：T38501产 地：中国大陆
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T38428Alisertib sodium；Alisertib sodiumMLN 8237 sodium；MLN 8237 sodium
Alisertib sodium (MLN 8237) is a potent and specific inhibitor (IC50 = 1.2 nM) of Aurora A kinase, an enzyme involved in cell division. By binding to Aurora A kinase, Alisertib sodium disrupts the formation of the mitotic spindle and causes abnormal cell division. At the molecular level, it acts on the AKT/mTOR/AMPK/p38 pathway, leading to the induction of apoptosis and autophagy in leukemic cells. This compound exhibits significant antitumor activity.
价 格：￥电议型 号：T38428产 地：中国大陆
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T3841Desrhamnosylmartynoside；化合物 T3841Desrhamnosylmartynoside
Desrhamnosylmartynoside is a natural product for research related to life sciences. The catalog number is T3841 and the CAS number is 136055-64-6.
价 格：￥电议型 号：T3841产 地：中国大陆
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T38407RTIL 13；RTIL 13RTIL 13
RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound effectively suppresses both receptor-mediated and synaptic vesicle endocytosis, demonstrating IC50 values of 9.3 μM and 7.1 μM, respectively.
价 格：￥电议型 号：T38407产 地：中国大陆
