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T75174Anti-inflammatory agent 42；抗炎剂42Anti-inflammatory agent 42
Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.
价 格：￥电议型 号：T75174产 地：中国大陆
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T75173WT-TTR inhibitor 1；化合物 WT-TTR inhibitor 1WT-TTR inhibitor 1
Compound 21, a WT-TTR (wild-type Transthyretin) inhibitor, exhibits a 29.05% inhibition rate at a concentration of 100 μM [1].
价 格：￥电议型 号：T75173产 地：中国大陆
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T75172Antibacterial agent 143；化合物 Antibacterial agent 143Antibacterial agent 143
Compound 5a (Antibacterial agent 143) is an antibacterial agent exhibiting minimum inhibitory concentrations (MICs) of 25 μg/mL against B. subtilis ATCC6633 and S. aureus ATCC6538, and 50 μg/mL against P. aeruginosa ATCC13525 and E. coli ATCC35218, demonstrating its effectiveness in inhibiting bacterial growth [1].
价 格：￥电议型 号：T75172产 地：中国大陆
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T75171BacPROTAC-1；化合物 BacPROTAC-1BacPROTAC-1
BacPROTAC-1, a potent mSA BacPROTAC degrader, exhibits high affinity for both mSA and the N-terminal domain (NTD) of ClpC, with dissociation constants (K D) of 3.9 μM and 2.8 μM, respectively [1].
价 格：￥电议型 号：T75171产 地：中国大陆
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T75170BI01826025；化合物 BI01826025BI01826025
BI01826025 (pArg-JQ1), a PROTAC degrader targeting the bromodomain 1 of BRDT (BRDT BD1), proves useful in exploring the regulatory impact of ClpC2 on the ClpC1P1P2 protease complex [1].
价 格：￥电议型 号：T75170产 地：中国大陆
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T75169SRG-II-19F；化合物 SRG-II-19FSRG-II-19F
SRG-II-19F (dCym-JQ1), a BRDT BD1 (bromodomain1 of BRDT) degrader, is utilized to examine the regulatory influence of ClpC2 on the ClpC1P1P2 protease [1].
价 格：￥电议型 号：T75169产 地：中国大陆
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T75168Homo-BacPROTAC7；化合物 Homo-BacPROTAC7Homo-BacPROTAC7
Homo-BacPROTAC7, a ClpC1 NTD BacPROTAC degrader, targets ClpC2 and efficiently kills M. tuberculosis [1].
价 格：￥电议型 号：T75168产 地：中国大陆
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T75167Homo-BacPROTAC6；化合物 Homo-BacPROTAC6Homo-BacPROTAC6
Homo-BacPROTAC6, a ClpC1 NTD BacPROTAC degrader, effectively targets ClpC2, while Homo-BacPROTAC7 has been shown to efficiently kill M. tuberculosis [1].
价 格：￥电议型 号：T75167产 地：中国大陆
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T75166Influenza virus-IN-7；化合物 Influenza virus-IN-7Influenza virus-IN-7
Influenza virus-IN-7 (Example 16) is an orally active inhibitor of cap-dependent endonuclease, employed in research on influenza viral infectious diseases [1].
价 格：￥电议型 号：T75166产 地：中国大陆
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T75165HER2-IN-14；化合物 HER2-IN-14HER2-IN-14
HER2-IN-14 (Compound 34) is a potent inhibitor of HER2, achieving an inhibitory concentration (IC50) of 18 nM. Additionally, this compound exhibits inhibitory activity against wild-type EGFR (wt-EGFR) with an IC50 of 6.3 μM [1].
价 格：￥电议型 号：T75165产 地：中国大陆
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T75164HER2-IN-13；化合物 HER2-IN-13HER2-IN-13
HER2-IN-13 (Compound 33) serves as an effective HER2 inhibitor, exhibiting an IC50 value of 8 nM, and additionally demonstrates inhibition of wt-EGFR with an IC50 of 0.40 μM [1].
价 格：￥电议型 号：T75164产 地：中国大陆
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T75163GW297361；化合物GW297361GW297361
GW297361 is a potent inhibitor of the cell cycle protein-dependent kinase Cdk1 and also inhibits the Pho85 signaling pathway.The IC50s of GW297361 on yeast Cdk1 and Pho85 were 20 nM and 400 nM, respectively.
价 格：￥电议型 号：T75163产 地：中国大陆
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T75162P2X2/3 modulator-1；化合物 P2X2/3 modulator-1P2X2/3 modulator-1
P2X2/3 Modulator-1 (Compound 46) serves as a modulator of P2X2/3 receptors and has applications in researching pain, central nervous system disorders, and inflammation [1].
价 格：￥电议型 号：T75162产 地：中国大陆
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T75161STING agonist-31；化合物 STING agonist-31STING agonist-31
STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively, demonstrating significant antitumor efficacy [1].
价 格：￥电议型 号：T75161产 地：中国大陆
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T75160FXR agonist 5；化合物 FXR agonist 5FXR agonist 5
FXR agonist 5 (compound 1), an FXR agonist, is utilized in research targeting diseases or disorders associated with metabolic inflammation [1].
价 格：￥电议型 号：T75160产 地：中国大陆
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T7516ZD7288；化合物ZD7288ICI D7288；N-乙基-1,6-二氢-1,2-二甲基-6-(甲基亚氨基)-N-苯基-4-嘧啶胺盐酸盐|||ICI D7288
ZD7288 (ICI D7288), a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity.
价 格：￥电议型 号：T7516产 地：中国大陆
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T75159Rosomidnar；化合物 RosomidnarRosomidnar
PNT100, a 24-base, chemically unmodified DNA oligonucleotide, targets the regulatory region upstream of the BCL-2 gene by being complementary to it. When tumor cells are exposed to PNT100, it leads to a suppression of proliferation and induces cell death.
价 格：￥电议型 号：T75159产 地：中国大陆
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T75158Olpasiran；化合物 OlpasiranOlpasiran
Olpasiran is a small interfering RNA that reduces lipoprotein(a) synthesis in the liver.
价 格：￥电议型 号：T75158产 地：中国大陆
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T75157LCimdelirsen sodium；化合物 Cimdelirsen sodiumCimdelirsen sodium
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
价 格：￥电议型 号：T75157L产 地：中国大陆
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T75157Cimdelirsen；化合物 CimdelirsenCimdelirsen
Cimdelirsen, a novel ligand-conjugated, hepatic-targeted antisense oligonucleotide under investigation, aims to diminish growth hormone receptor (GHr) synthesis. This inhibits the harmful effects of growth hormone (GH) hypersecretion and lowers circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
价 格：￥电议型 号：T75157产 地：中国大陆
