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  • T75156LBevasiranib sodium；化合物 Bevasiranib sodiumBevasiranib sodium

    Bevasiranib sodium, an siRNA compound, targets and silences the genes responsible for producing vascular endothelial growth factor (VEGF). The suppression of VEGF, a critical factor in the development of choroidal neo-vascularization (CNV), aims to thwart the progression to wet age-related macular degeneration (wet AMD).

    价 格：￥电议型 号：T75156L产 地：中国大陆

  • T75156Bevasiranib；化合物 BevasiranibBevasiranib

    Bevasiranib, a siRNA, is specifically engineered to suppress the expression of genes responsible for the production of vascular endothelial growth factor (VEGF), a critical factor in the development of choroidal neo-vascularization (CNV), which precedes wet age-related macular degeneration (wet AMD).

    价 格：￥电议型 号：T75156产 地：中国大陆

  • T75155Bamosiran；化合物 BamosiranBamosiran

    Bamosiran, a small interfering RNA (siRNA), specifically targets the β-adrenergic receptor 2 to reduce intraocular pressure.

    价 格：￥电议型 号：T75155产 地：中国大陆

  • T75154ATU027；化合物 ATU027ATU027

    ATU027, a small interfering RNA (siRNA), silences protein kinase N3 (PKN3) expression in the vascular endothelium. It has been demonstrated to thwart local tumor invasion, as well as lymph node and pulmonary metastasis, in mouse cancer models.

    价 格：￥电议型 号：T75154产 地：中国大陆

  • T75153ATL 1102；化合物 ATL 1102ATL 1102

    ATL 1102 is a novel second-generation antisense oligonucleotide to CD49d mRNA

    价 格：￥电议型 号：T75153产 地：中国大陆

  • T75152ARC19499；化合物 ARC19499ARC19499

    ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor Xa and the TF/factor VIIa complex, thereby correcting thrombin generation in hemophilia A and B plasma and restoring clotting in FVIII-neutralized whole blood.

    价 格：￥电议型 号：T75152产 地：中国大陆

  • T75151Aganirsen；化合物 AganirsenAganirsen

    Aganirsen, a 25-mer DNA antisense oligonucleotide, silences the expression of insulin receptor substrate-1 (IRS-1).

    价 格：￥电议型 号：T75151产 地：中国大陆

  • T75150GIP/GLP-1 dual receptor agonist-1；化合物 GIP/GLP-1 dual receptor agonist-1GIP/GLP-1 dual receptor agoni

    GIP/GLP-1 dual receptor agonist-1 (compound 4), a receptor agonist for both GIP and GLP-1, shows potential for the research of metabolic disorders and fatty liver diseases, such as nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) [1].

    价 格：￥电议型 号：T75150产 地：中国大陆

  • T7515MTEP hydrochloride；3-[2-(2-甲基-4-噻唑基)乙炔基]吡啶盐酸盐3-((2-Methyl-1,3-thiazol-4-yl)ethyn-yl)pyridine hydroch

    MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)

    价 格：￥电议型 号：T7515产 地：中国大陆

  • T75149PROTAC BRD4 Degrader-19；化合物 PROTAC BRD4 Degrader-19PROTAC BRD4 Degrader-19

    PROTAC BRD4 Degrader-19 (compound 176) is a proteolysis-targeting chimera (PROTAC) designed to specifically degrade the BRD4 protein, offering potential utility in cancer research [1].

    价 格：￥电议型 号：T75149产 地：中国大陆

  • T75148Hedgehog IN-3；化合物 Hedgehog IN-3Hedgehog IN-3

    Hedgehog IN-3 (compound 3), with an IC50 value of 0.01 ?M, serves as a hedgehog pathway inhibitor, proving beneficial for cancer research applications [1].

    价 格：￥电议型 号：T75148产 地：中国大陆

  • T75147PCSK9-IN-18；化合物 PCSK9-IN-18PCSK9-IN-18

    PCSK9-IN-18 (compound 188) is a potent PCSK9 inhibitor with a K D value of <200 nM [1] .

    价 格：￥电议型 号：T75147产 地：中国大陆

  • T75146KAT6-IN-1；化合物 KAT6-IN-1KAT6-IN-1

    KAT6-IN-1 is a potent KAT6 inhibitor. KAT6-IN-1 can be used in research of cancer [1] .

    价 格：￥电议型 号：T75146产 地：中国大陆

  • T75145TRV-7019；化合物 TRV-7019TRV-7019

    TRV-7019 is a butyrylcholinesterase-targeting radioligand capable of penetrating the blood-brain barrier (BBB) for brain imaging. It is utilized for diagnosing conditions such as amyloid diseases, multiple sclerosis, brain tumors, or to assess butyrylcholinesterase activity [1].

    价 格：￥电议型 号：T75145产 地：中国大陆

  • T75144WU-FA-01；化合物 WU-FA-01WU-FA-01

    WU-FA-01, a hydrogenated derivative of WU-FA-00, functions as an antibacterial agent with robust activity against Gram-positive strains and possesses anti-inflammatory properties [1].

    价 格：￥电议型 号：T75144产 地：中国大陆

  • T75143Mcl-1 inhibitor 12；化合物 Mcl-1 inhibitor 12Mcl-1 inhibitor 12

    Mcl-1 Inhibitor 12 (Example 10), with a K i of 0.22 nM, functions as an MCL-1 inhibitor. It is utilized in cancer research [1].

    价 格：￥电议型 号：T75143产 地：中国大陆

  • T75142Acid Ceramidase-IN-2；化合物 Acid Ceramidase-IN-2Acid Ceramidase-IN-2

    Acid Ceramidase-IN-2 (compound 1), an acid ceramidase inhibitor, exhibits potentially antiproliferative and cytostatic effects. This compound is of interest due to the overexpression of human acid ceramidase in prostate cancer cells, suggesting its potential anti-tumor efficacy. Furthermore, the hydrolysis of Acid Ceramidase-IN-2 can be inhibited by 3 a-ketoamides: GT85, GT98, and GT99 in vitro [1].

    价 格：￥电议型 号：T75142产 地：中国大陆

  • T75141Aflatoxin Q1；化合物 Aflatoxin Q1Aflatoxin Q1

    Aflatoxin Q1, a hydroxy metabolite of Aflatoxin B1 (AFB1)—a mycotoxin synthesized by Aspergillus flavus (A. flavus)—and aflatoxin B1 8,9-oxide are principal oxidative derivatives produced from Aflatoxin B1 in human liver microsomes across all substrate concentrations. The conversion of Aflatoxin B1 to Aflatoxin Q1 through 3 alpha-hydroxylation represents a critical detoxification route [1] [2].

    价 格：￥电议型 号：T75141产 地：中国大陆

  • T75140CPD-1224；化合物 CPD-1224CPD-1224

    CPD-1224, an orally active derivative that binds cereblon ligands to ALK inhibitors, specifically targets and degrades EML4-ALK oncogenic fusions, including ALK and its mutants L1196M/G1202R.

    价 格：￥电议型 号：T75140产 地：中国大陆

  • T7514N2-Methylguanosine2-甲鳥苷2-甲鳥苷

    N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA´s

    价 格：￥电议型 号：T7514产 地：中国大陆

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