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  • T7512BMS-191011；化合物BMS-191011BMS-A；BMS-A

    BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models

    价 格：￥电议型 号：T7512产 地：中国大陆

  • T75119KRASG12Cu00A0IN-2；化合物 KRASG12Cu00A0IN-2KRASG12Cu00A0IN-2

    KRASG12C IN-2 (compound 17) is an orally active inhibitor of KRAS G12C, which effectively suppresses tumor growth in mice [1].

    价 格：￥电议型 号：T75119产 地：中国大陆

  • T75118AN15368；化合物 AN15368AN15368

    AN15368, an orally administered small-molecule precursor, undergoes activation by parasite carboxypeptidase, yielding a product that interferes with the messenger RNA processing pathway in T. cruzi. This compound shows promise for both preventing and investigating potential treatments for Chagas disease [1].

    价 格：￥电议型 号：T75118产 地：中国大陆

  • T75117Py-MAA-Val-Cit-PAB-DX8951；化合物 Py-MAA-Val-Cit-PAB-DX8951Py-MAA-Val-Cit-PAB-DX8951

    Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].

    价 格：￥电议型 号：T75117产 地：中国大陆

  • T75116COVID-19 Spike Protein mRNA-LNP；化合物 COVID-19 Spike Protein mRNA-LNPCOVID-19 Spike Protein mRNA-LNP

    COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) formulated with the novel coronavirus pneumonia spike protein, positioned on the membrane surface, designed for applications such as RNA delivery, translation efficiency, and cell viability assessment. This spike protein facilitates the COVID-19 virus´s entry into host cells by binding to cell membrane receptors and enabling membrane fusion, making it a critical focal point for host neutralizing antibodies and vaccine developmen

    价 格：￥电议型 号：T75116产 地：中国大陆

  • T75115CD19 car circRNA-LNP；化合物 CD19 car circRNA-LNPCD19 car circRNA-LNP

    CD19 car circRNA-LNP, a lipid nanoparticle containing CD19 car circRNA, is designed for applications in RNA delivery, translation efficiency, and cell viability assessment. This compound is utilized in chimeric antigen receptor T cell immunotherapy (CAR-CD19), leveraging CD19 car, a chimeric antigen receptor that targets CD19. CD19, a CD molecule found on B cells (i.e., leukocyte differentiation antigen), plays a crucial role in B cell proliferation, differentiation, activation, and antibody pro

    价 格：￥电议型 号：T75115产 地：中国大陆

  • T75114CD19 car mRNA-LNP；化合物 CD19 car mRNA-LNPCD19 car mRNA-LNP

    CD19 car mRNA-LNP, a lipid nanoparticle (LNP) encapsulating CD19 car mRNA, is instrumental in assessing RNA delivery, translation efficacy, and cell viability among other applications. This compound is pivotal for chimeric antigen receptor T cell immunotherapy (CAR-CD19), leveraging the CD19 molecule - a critical membrane antigen expressed by B cells (i.e., leukocyte differentiation antigen) that plays a significant role in their proliferation, differentiation, activation, and antibody productio

    价 格：￥电议型 号：T75114产 地：中国大陆

  • T75113GLPG2534；化合物GLPG2534GLPG-2534；GLPG-2534

    GLPG2534 is an orally active, selective and potent IRAK4 inhibitor with anti-inflammatory activity. GLPG2534 inhibits human and mouse IRAK4 and could be used to study psoriasis and atopic dermatitis.

    价 格：￥电议型 号：T75113产 地：中国大陆

  • T75112LSN3160440；化合物 LSN3160440LSN3160440

    LSN3160440 is an allosteric modulator of GLP-1R, functioning as a protein-protein interaction (PPI) stabilizer or molecular glue. It aids in the binding of inactive GLP-1 (9-36) NH2 to GLP-1R, enhancing receptor activation and potential therapeutic effects [1] [2].

    价 格：￥电议型 号：T75112产 地：中国大陆

  • T75111LNP Lipid-4；化合物 LNP Lipid-4LNP Lipid-4

    LNP Lipid-4 (Compound 8-8) is a lipid compound with a crucial role in the synthesis of lipid nanoparticle compositions, demonstrating potential for the transport of biologically active substances [1].

    价 格：￥电议型 号：T75111产 地：中国大陆

  • T75110Trametiglue；化合物 TrametiglueTrametiglue

    Trametiglue, a Trametinib derivative, exhibits exceptional potency and selectivity in targeting KSR-MEK and RAF-MEK through distinctive interfacial binding interactions [1].

    价 格：￥电议型 号：T75110产 地：中国大陆

  • T7511Cyclo(his-pro)；化合物Cyclo(his-pro)Cyclo(his-pro)

    Cyclo(his-pro) is an endogenous cyclic dipeptide that exerts oxidative damage protection by selectively activating the transcription factor Nrf2 signalling pathway.

    价 格：￥电议型 号：T7511产 地：中国大陆

  • T75109HECT E3-IN-1；化合物 HECT E3-IN-1HECT E3-IN-1

    HECT E3-IN-1 (compound 3) is a HECT E3 ligase inhibitor that impedes Ub binding at the non-covalent Ub-binding site of Nedd4-1 [1].

    价 格：￥电议型 号：T75109产 地：中国大陆

  • T75108LNP Lipid-1；化合物 LNP Lipid-1LNP Lipid-1

    LNP Lipid-1 (Method B), a lipid compound, plays a crucial role in the formulation of lipid nanoparticles compositions and exhibits potential for transporting biologically active substances, including small molecule agents, proteins, and nucleic acids [1] [2].

    价 格：￥电议型 号：T75108产 地：中国大陆

  • T75107CrBKA；化合物 CrBKACrBKA

    CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .

    价 格：￥电议型 号：T75107产 地：中国大陆

  • T75106ARC186；化合物 ARC186ARC186

    ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.

    价 格：￥电议型 号：T75106产 地：中国大陆

  • T75105OICR12694 TFA；化合物 OICR12694 TFAOICR12694 TFA

    OICR12694 (JNJ-65234637) TFA, an orally active B cell lymphoma 6 (BCL6) inhibitor [1], demonstrates effectiveness in targeting BCL6 pathways.

    价 格：￥电议型 号：T75105产 地：中国大陆

  • T75104CD19 CAR circRNA；化合物 CD19 CAR circRNACD19 CAR circRNA

    CD19 CAR circRNA, expressing CD19 car protein, is utilized in chimeric antigen receptor T cell immunotherapy (CAR-CD19). This compound involves a chimeric antigen receptor, CD19, a CD molecule present on B cells (i.e., leukocyte differentiation antigen), crucial for B cell proliferation, differentiation, activation, and antibody production, and facilitates BCR signal transduction.

    价 格：￥电议型 号：T75104产 地：中国大陆

  • T75103CD19 CAR mRNA；化合物 CD19 CAR mRNACD19 CAR mRNA

    CD19 CAR mRNA is designed to express the CD19 chimeric antigen receptor (CAR) protein, pivotal in chimeric antigen receptor T cell (CAR-CD19) immunotherapy. This receptor targets CD19, a membrane antigen crucial for B cell proliferation, differentiation, activation, and antibody synthesis, playing a significant role in promoting BCR signal transduction.

    价 格：￥电议型 号：T75103产 地：中国大陆

  • T75102COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)；化合物 COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)COVID

    The COVID-19 Spike Protein mRNA, responsible for expressing the COVID-19 spike protein, is crucial for evaluating RNA delivery, translation efficiency, and cell viability. Positioned on the membrane surface, this spike protein facilitates virus entry into cells by binding to host cell membrane receptors and promoting membrane fusion. It serves as a significant action site for neutralizing antibodies and represents a primary focus in vaccine development [1].

    价 格：￥电议型 号：T75102产 地：中国大陆

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