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  • T14677BMS-690514BMS-690514

    BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.

    价 格：￥电议型 号：T14677产 地：美洲

  • T14681BMS-935177BMS-935177

    BMS-935177 is a potent and selective reversible inhibitor of Bruton’s tyrosine kinase (Btk), with an IC50 of 3 nM.

    价 格：￥电议型 号：T14681产 地：美洲

  • T14683BMS-983970BMS-983970

    BMS-983970 is an oral pan-Notch inhibitor. Which is used for treatment of multiplecancers.

    价 格：￥电议型 号：T14683产 地：美洲

  • T14685BMS-986158BMS-986158

    BMS-986158 is a potent BET inhibitor. With IC50s of 6.6 and 5?nM in NCI-H211 small cell lung cancer (SCLC) cells and MDA-MB231 triple negative breast cancer (TNBC) cells, respectively[1].

    价 格：￥电议型 号：T14685产 地：美洲

  • T14687BMS-986165BMS-986165

    BMS-986165 inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM)

    价 格：￥电议型 号：T14687产 地：美洲

  • T14688BMS CCR2 22BMS CCR2 22

    BMS CCR2 22 is a potent, specific and high affinity CC-type chemokine receptor 2 (CCR2) antagonist. It has excellent binding affinity (binding IC50 of 5.1 nM) and potent functional antagonism (calcium flux IC50 of 18 nM and chemotaxis IC50 of 1 nM)[1][2].

    价 格：￥电议型 号：T14688产 地：美洲

  • T14967CimlanodCimlanod,BMS-986231,CXL-1427

    Cimlanod has positive lusitropic and inotropic as well as vasodilatory effects. Cimlanod is a second-generation Nitroxyl (HNO) donor for heart failure. Cimlanod delivers HNO via pH-dependent chemical breakdown, when exposed to the neutral pH environment

    价 格：￥电议型 号：T14967产 地：美洲

  • T15286FlindokalnerFlindokalner,BMS-204352,

    Flindokalner is a potassium channel modulator and it also is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner

    价 格：￥电议型 号：T15286产 地：美洲

  • T1615IrbesartanIrbesartan,BMS-186295,SR-47436

    Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.

    价 格：￥电议型 号：T1615产 地：美洲

  • T16385OmapatrilatOmapatrilat,BMS-186716,

    Omapatrilat is a metalloprotease ACE and NEP dual inhibitor (Ki: 0.64 and 0.45 nM, respectively).

    价 格：￥电议型 号：T16385产 地：美洲

  • T1736ApixabanApixaban,BMS-562247-01,

    Apixaban is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing the formation of cross-linked fibrin clots

    价 格：￥电议型 号：T1736产 地：美洲

  • T1786Daclatasvir dihydrochlorideDaclatasvir dihydrochloride,BMS-790052 dihydrochloride,

    Daclatasvir is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) and is used in combination with other oral antiviral agents to treat chronic hepatitis C. Elevations in serum enzyme levels during daclatasvir

    价 格：￥电议型 号：T1786产 地：美洲

  • T2299BMS-833923BMS-833923,BMS833923,BMS 833923

    BMS-833923, an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).

    价 格：￥电议型 号：T2299产 地：美洲

  • T2337BMS-303141BMS-303141,BMS303141,BMS 303141

    BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor (IC50: 0.13 uM, human recombinant ACL).

    价 格：￥电议型 号：T2337产 地：美洲

  • T2349BMS-754807BMS-754807,BMS754807,BMS 754807

    Dual IGF-1R/InsR Inhibitor BMS-754807 is an oral small molecule inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (InsR) tyrosine kinases with potential antineoplastic activity.

    价 格：￥电议型 号：T2349产 地：美洲

  • T2389DapagliflozinDapagliflozin,BMS-512148,

    Dapagliflozin is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.

    价 格：￥电议型 号：T2389产 地：美洲

  • T2419BMS794833BMS794833

    BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.

    价 格：￥电议型 号：T2419产 地：美洲

  • T2545Lomitapide MesylateLomitapide Mesylate,BMS-201038 mesylate,AEGR-733 mesylate

    Lomitapide Mesylate is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.

    价 格：￥电议型 号：T2545产 地：美洲

  • T2576Brivanib AlaninateBrivanib Alaninate,BMS-582664,

    Brivanib Alaninate is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively

    价 格：￥电议型 号：T2576产 地：美洲

  • T2586CabozantinibCabozantinib,BMS-907351,XL184

    Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50s: 0.035, 1.3, 4.6, 7 and 11.3 nM).

    价 格：￥电议型 号：T2586产 地：美洲

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