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T76741Eldelumab;埃迪鲁单抗BMS-936557|||MDX-1100;BMS-936557|||MDX-1100
Eldelumab (BMS-936557) is a humanized anti-IP-10 IgG type 1 monoclonal antibody with inhibitory activity against CXCL10.Eldelumab has anti-inflammatory activity and selectively binds to CXCL10 and can be used in the study of rheumatoid arthritis, ulcerative colitis, and Crohn´s disease.
价 格:¥电议型 号:T76741产 地:中国大陆
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T7512BMS-191011;化合物BMS-191011BMS-A;BMS-A
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
价 格:¥电议型 号:T7512产 地:中国大陆
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T74185(S,S)-BMS-984923;化合物 (S,S)-BMS-984923(S,S)-BMS-984923
(S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923. (S,S)-BMS-984923 shows an EC 50 >1μM for mGluR5 receptor [1] . BMS-984923 is a potent mGluR5 silent allosteric modulator [2] .
价 格:¥电议型 号:T74185产 地:中国大陆
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T73155BMS-986339;化合物 BMS-986339BMS-986339
BMS-986339 is an orally active, potent FXR agonist that interacts via H-bond formation with the His298 and ASN287 residues. It is utilized in research focused on primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH) for its anti-fibrosis properties.
价 格:¥电议型 号:T73155产 地:中国大陆
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T73092Udifitimod;化合物 UdifitimodBMS-986166;BMS-986166
Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.
价 格:¥电议型 号:T73092产 地:中国大陆
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T7309TAS-103 dihydrochloride;化合物TAS-103 (dihydrochloride)TAS-103 (dihydrochloride)|||BMS-247615 dihydroch
TAS-103 dihydrochloride (BMS-247615 dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.
价 格:¥电议型 号:T7309产 地:中国大陆
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T73084BMS 310705;化合物 BMS 31070521-Aminoepothilone B;21-Aminoepothilone B
BMS 310705 (21-Aminoepothilone B), an Epothilone B analog, specifically targets malignancies including ovarian, renal, bladder, and lung carcinoma. It significantly induces apoptosis through the mitochondrial-mediated pathway [1].
价 格:¥电议型 号:T73084产 地:中国大陆
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T72462(2S,5S)-Censavudine;化合物 (2S,5S)-Censavudine(2S,5S)-OBP-601 ; (2S,5S)-BMS-986001|||(2S,5S)-BMS-98600
(2S,5S)-Censavudine ((2S,5S)-OBP-601), the (2S,5S)-enantiomer of Censavudine, is a nucleoside reverse transcriptase inhibitor and a potent HIV inhibitor.
价 格:¥电议型 号:T72462产 地:中国大陆
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T72399LIMK1 inhibitor BMS-4;化合物 LIMK1 inhibitor BMS-4LIMK1 inhibitor BMS-4
LIMK1 inhibitor BMS-4 is a compound targeting LIM Kinase (LIMK) 1/2, specifically inhibiting the phosphorylation of its substrate, cofilin, but it remains noncytotoxic on A549 cells.
价 格:¥电议型 号:T72399产 地:中国大陆
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T72249BMS-823778 hydrochloride;化合物 BMS-823778 hydrochlorideBMS-823778 hydrochloride
BMS-823778 hydrochloride is a potent, selective, and orally active inhibitor of 11β-HSD1 (11β-Hydroxysteroid Dehydrogenase Type 1), demonstrating an IC50 (half maximal inhibitory concentration) of 2.3 nM against the human form of the enzyme.
价 格:¥电议型 号:T72249产 地:中国大陆
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T7221Satraplatin;沙铂BMS182751|||JM216|||BMY45594;BMS182751|||JM216|||顺式-二氯-反式-二乙酸-氨-环己胺合铂|||BMY45594
Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against a variety of malignancies.
价 格:¥电议型 号:T7221产 地:中国大陆
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T7179Garenoxacin;加雷沙星BMS284756;BMS284756|||加雷沙星
Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.
价 格:¥电议型 号:T7179产 地:中国大陆
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T71670(rel)-BMS-641988;化合物 BMS-641988(rel)-BMS-641988
(rel)-BMS-641988, a relative configuration of the potent nonsteroidal androgen receptor antagonist BMS-641988, holds potential for prostate cancer research.
价 格:¥电议型 号:T71670产 地:中国大陆
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T71641BMS-593214;化合物 BMS-593214BMS-593214
BMS-593214 is an active site-directed factor (F) VIIa inhibitor that exhibits antithrombotic and antihaemostatic properties. It acts as a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. Moreover, BMS-593214 effectively prevents electroinduced carotid artery thrombosis (AT) and wire-induced vena cava thrombosis (VT).
价 格:¥电议型 号:T71641产 地:中国大陆
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T71640BMS-741672;化合物 BMS-741672BMS-741672
BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.
价 格:¥电议型 号:T71640产 地:中国大陆
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T7152Ravuconazole;雷夫康唑BMS-207147|||ER-30346;立福康唑|||雷夫康唑|||BMS-207147|||ER-30346
Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.
价 格:¥电议型 号:T7152产 地:中国大陆
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T71394BMS-823778;化合物 BMS-823778BMS-823778
BMS-823778 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) for the study of type 2 diabetes.
价 格:¥电议型 号:T71394产 地:中国大陆
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T71339XL413 HCl;XL413 盐酸盐XL413 hydrochloride|||BMS-863233 HCl;XL413 hydrochloride|||BMS-863233 HCl
XL413 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.XL413 HCl inhibited CK2 and PIM1 with IC50 values of 215 and 42 nM, respectively.XL413 HCl showed an EC50 value of 118 against pMCM.
价 格:¥电议型 号:T71339产 地:中国大陆
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T71294BMS-763534;化合物 BMS-763534BMS-763534
BMS-763534 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).
价 格:¥电议型 号:T71294产 地:中国大陆
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T71265BMS-830216;化合物 BMS-830216BMS-830216
BMS-830216 is a nonbasic melanin hormone receptor 1 antagonist and a prodrug of BMS-819881.
价 格:¥电议型 号:T71265产 地:中国大陆