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T2357GSK-1059615GSK-1059615,GSK1059615,GSK 1059615
GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.
价 格:¥电议型 号:T2357产 地:美洲
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T2701GSK1292263GSK1292263
GSK1292263 is a GPR119 agonist and has been investigated for the treatment of DIABETES MELLITUS, TYPE 2.
价 格:¥电议型 号:T2701产 地:美洲
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T4S1499Ginsenoside Rk1Ginsenoside Rk1
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures. Ginsenoside Rk1 has an anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB. It also has an anti-tumor effect.
价 格:¥电议型 号:T4S1499产 地:美洲
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T5093Pim1/AKK1-IN-1Pim1/AKK1-IN-1,LKB1/AAK1 dual inhibitor,MDK-2275
Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
价 格:¥电议型 号:T5093产 地:美洲
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T5193DanirixinDanirixin,GSK1325756,
Danirixin is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).
价 格:¥电议型 号:T5193产 地:美洲
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T5393CK1-IN-1CK1-IN-1,PUN51207,
CK1-IN-1, compound 1c reported in patent WO2015119579A1, is a casein kinase 1 (CK1) inhibitor. It has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively.
价 格:¥电议型 号:T5393产 地:美洲
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T5427GSK1940029GSK1940029,SCD inhibitor 1,
GSK1940029 is a stearoyl-coa desaturase (SCD) inhibitor.
价 格:¥电议型 号:T5427产 地:美洲
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T6003GSK1904529AGSK1904529A,GSK 4529,
GSK1904529A is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
价 格:¥电议型 号:T6003产 地:美洲
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T6021GSK1324726AGSK1324726A,I-BET726,
GSK1324726A is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).
价 格:¥电议型 号:T6021产 地:美洲
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T6098CabotegravirCabotegravir,S/GSK1265744,GSK-1265744
Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).
价 格:¥电议型 号:T6098产 地:美洲
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T6176IKK-16IKK-16,IKK16,IKK 16
IKK-16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
价 格:¥电议型 号:T6176产 地:美洲
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T6198DolutegravirDolutegravir,GSK1349572,S/GSK1349572
Dolutegravir (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
价 格:¥电议型 号:T6198产 地:美洲
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T6440CGP 57380CGP 57380,MNK1 Inhibitor,
CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.
价 格:¥电议型 号:T6440产 地:美洲
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T8786VUT-MK142;化合物VUT-MK142VUT-MK142
VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.
价 格:¥电议型 号:T8786产 地:中国大陆
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T8472ERK1/2 inhibitor 2;化合物ASTX029ASTX-029|||ASTX029;ASTX-029|||ASTX029
ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable extracellular signal-regulated kinases 1 and 2 (ERK 1/2) inhibitor, with potential antineoplastic activity.
价 格:¥电议型 号:T8472产 地:中国大陆
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T8424TLK117;化合物 T8424TER117;TER117
TLK117 selective inhibits Glutathione S-transferase P1–1 (GSTP1-1)(Ki of 0.4 μM for GSTP).
价 格:¥电议型 号:T8424产 地:中国大陆
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T8418DCLK1-IN-1;化合物DCLK1-IN-1DCLK1-IN-1
DCLK1-IN-1 is a selective and in vivo-compatible chemical probe of the DCLK1 kinase domain .
价 格:¥电议型 号:T8418产 地:中国大陆
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T8408GKT136901;化合物GKT136901AK120765;AK120765
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
价 格:¥电议型 号:T8408产 地:中国大陆
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T83491[K15,R16,L27]VIP(1-7)/GRF(8-27);化合物 [K15,R16,L27]VIP(1-7)/GRF(8-27)[K15,R16,L27]VIP(1-7)/GRF(8-27)
[K15,R16,L27]VIP(1-7)/GRF(8-27), a selective agonist for the VIP 1 receptor, demonstrates binding IC 50 values of 2 nM for the human VIP 1, 1 nM for the rat VIP 1, and 30,000 nM for the rat VIP 2 receptors, respectively [1]. VIP stands for VASOACTIVE Intestinal Polypeptide.
价 格:¥电议型 号:T83491产 地:中国大陆
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T8346311(α)-Hydroxynepasaikosaponin k;化合物 11(α)-Hydroxynepasaikosaponin k11(α)-Hydroxynepasaikosaponin k
11(α)-Hydroxynepasaikosaponin K (HOSSc) is a saikosaponin derived from Bupleurum scorzonerifolium Willd [1].
价 格:¥电议型 号:T83463产 地:中国大陆