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  • T82513EAK16-II;化合物 EAK16-IIEAK16-II

    EAK16-II, an amphipathic peptide, concentration-dependently inhibits the self-sorting of EAKIIH6 [1].

    价 格:¥电议型 号:T82513产 地:中国大陆

  • T82412FC382K10W15;化合物 FC382K10W15FC382K10W15

    FC382K10W15, a glucagon derivative, is valuable for research in diabetes [1].

    价 格:¥电议型 号:T82412产 地:中国大陆

  • T82393FLT3/CHK1-IN-1;化合物 FLT3/CHK1-IN-1FLT3/CHK1-IN-1

    Compound 18, also known as FLT3/CHK-IN-1, is a dual inhibitor targeting FLT3 and CHK1, exhibiting over 1700-fold selectivity towards c-KIT and significantly diminishing hERG affinity, with an IC50 of 58.4 μM. It demonstrates efficacy in suppressing tumor growth in mouse xenotransplantation models implanted with MV-4-11 cells [1].

    价 格:¥电议型 号:T82393产 地:中国大陆

  • T81999K1 peptide TFA;化合物 K1 peptide TFAK1 peptide TFA

    K1 peptide TFA exhibits high affinity as a ligand for the GABAA receptor-associated protein (GABARAP) [1].

    价 格:¥电议型 号:T81999产 地:中国大陆

  • T81998K1833;化合物 K1833K1833

    K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$. Additionally, K1833 demonstrates potent inhibition (IC50 = 0.57$) and minimal reactivation of human butyrylcholinesterase (hrBChE) [1].

    价 格:¥电议型 号:T81998产 地:中国大陆

  • T81701Nardoguaianone K;化合物 Nardoguaianone K10-epi-Nardoguaianone J;10-epi-Nardoguaianone J

    Nardoguaianone K, a guaiane-type sesquiterpenoid isolated from the roots of Nardostachys chinensis, has potential applications in pancreatic cancer research [1] [2].

    价 格:¥电议型 号:T81701产 地:中国大陆

  • T81580Ozanezumab;化合物 OzanezumabGSK1223249;GSK1223249

    Ozanezumab (GSK1223249) is a monoclonal antibody targeting Nogo-A (neurite outgrowth inhibitor A). It is utilized in research related to amyotrophic lateral sclerosis (ALS) and multiple sclerosis [1].

    价 格:¥电议型 号:T81580产 地:中国大陆

  • T81441PLK1/p38γ-IN-1;化合物 PLK1/p38γ-IN-1PLK1/p38γ-IN-1

    PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellular carcinoma and hepatoblastoma cell lines in vitro [1].

    价 格:¥电议型 号:T81441产 地:中国大陆

  • T81440PLK1-IN-7;化合物 PLK1-IN-7PLK1-IN-7

    PLK1-IN-7 (compound 30e) is a potent inhibitor exhibiting an IC50 value of 0.66 nM and demonstrates significant antiproliferative and antitumor activities [1].

    价 格:¥电议型 号:T81440产 地:中国大陆

  • T81269RIPK1-IN-16;化合物 RIPK1-IN-16RIPK1-IN-16

    RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo. It shields mice from TNF-induced systemic inflammatory response syndrome and sepsis [1].

    价 格:¥电议型 号:T81269产 地:中国大陆

  • T81268RIPK1-IN-17;化合物 RIPK1-IN-17RIPK1-IN-17

    RIPK1/3-IN-1 (Compound 10) is a selective inhibitor of both RIPK1 and RIPK3, effectively preventing necroptosis by blocking the phosphorylation of RIPK1, RIPK3, and MLKL [1].

    价 格:¥电议型 号:T81268产 地:中国大陆

  • T80608Ebronucimab;化合物 EbronucimabAK102;AK102

    Ebronucimab (AK102), an IgG1-λ2 antibody, specifically targets PCSK9 and is predominantly produced in CHO DG44 (Chinese Hamster Ovary) cells [1].

    价 格:¥电议型 号:T80608产 地:中国大陆

  • T80543STE-MEK1(13);化合物 STE-MEK1(13)ERK Activation Inhibitor Peptide|||Ste-MPKKKPTPIQLNP-NH?;ERK Activation

    STE-MEK1(13), a cell-permeable ERK1/2 inhibitor with IC50 values ranging from 13 to 30 μM, impedes the phosphorylation of ERK1/2, as demonstrated in studies [1] [2].

    价 格:¥电议型 号:T80543产 地:中国大陆

  • T80385K11;化合物 K11K11

    K11, an antimicrobial peptide, demonstrates activity against MDR/XDR K. pneumoniae isolates (MIC: 8-512 μg/mL) and inhibits bacterial biofilm formation. It also acts synergistically with various antibiotics (Chloramphenicol, Meropenem, Rifampicin, etc.) to combat drug-resistant K. pneumoniae and exhibits high thermal and wide pH stability [1].

    价 格:¥电议型 号:T80385产 地:中国大陆

  • T80193Enterocin Hybrid 1;化合物 Enterocin Hybrid 1K1-EJ hybrid;K1-EJ hybrid

    Enterocin Hybrid 1, an antibacterial agent, effectively inhibits Vancomycin-resistant Enterococcus faecium and Staphylococcus haemolyticus [1].

    价 格:¥电议型 号:T80193产 地:中国大陆

  • T80192Enterocin K1;化合物 Enterocin K1EntK1;EntK1

    Enterocin K1 (EntK1) is a ribosomally synthesized bacteriocin that exerts potent antibacterial activity against Vancomycin-resistant Enterococcus (VRE). It targets Enterococcus faecalis by interacting with the Eep protein on the bacterial membrane. The compound holds potential for research into VRE infections [1].

    价 格:¥电议型 号:T80192产 地:中国大陆

  • T80062Mitogen-activated protein kinase 1;化合物 Mitogen-activated protein kinase 1MAPK1;MAPK1

    Mitogen-activated protein kinase 1 (MAPK1) activates the p38/NF-κB pathway and regulates cellular processes in sepsis-associated diseases. Its catalytic action phosphorylates substrate proteins, serving as a regulatory switch for their activity [1].

    价 格:¥电议型 号:T80062产 地:中国大陆

  • T79790ALPK1-IN-3;化合物 ALPK1-IN-3ALPK1-IN-3

    ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced acute kidney injury [1].

    价 格:¥电议型 号:T79790产 地:中国大陆

  • T79788HPK1-IN-38;化合物 HPK1-IN-38HPK1-IN-38

    HPK1-IN-38 (compound 15) is an inhibitor of MAP4K1/HPK1, suitable for research into disorders related to HPK1 [1].

    价 格:¥电议型 号:T79788产 地:中国大陆

  • T79787HPK1-IN-37;化合物 HPK1-IN-37HPK1-IN-37

    HPK1-IN-37 (compound A85), with an IC50 value of 3.7 nM, is a potent inhibitor of HPK1. It is suitable for research purposes involving HPK1-associated diseases and disorders, notably cancers [1].

    价 格:¥电议型 号:T79787产 地:中国大陆

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