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T7951TBK1/IKKε-IN-5;化合物TBK1/IKKε-IN-5TBK1/IKKε-IN-5
TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).
价 格:¥电议型 号:T7951产 地:中国大陆
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T79421DCLK1-IN-2;化合物 DCLK1-IN-2DCLK1-IN-2
DCLK1-IN-2 (Compound I-5) is a potent inhibitor of DCLK1, exhibiting an IC50 of 171.3 nM, and demonstrates significant antiproliferative effects on SW1990 cell lines with an IC50 of 0.6 μM, as well as in vivo antitumor potency [1].
价 格:¥电议型 号:T79421产 地:中国大陆
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T79145CK1-IN-2;化合物 CK1-IN-2CK1-IN-2
CK1-IN-2 (compound Nr.4) is a potent inhibitor of CK1, exhibiting IC50 values of 123 nM for CK1a, 19.8 nM for CK1d, 26.8 nM for CK1e, and 74.3 nM for p38a [1].
价 格:¥电议型 号:T79145产 地:中国大陆
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T79144PROTAC MEK1 Degrader-1;化合物 PROTAC MEK1 Degrader-1PROTAC MEK1 Degrader-1
PROTAC MEK1 Degrader-1, a targeted protein degradation agent, combines a MEK1 inhibitor with a von Hippel-Lindau ligand to effectively inhibit ERK1/2 phosphorylation. With a pIC50 value of 7.0, it exhibits antiproliferative activity against A375 cells [1].
价 格:¥电议型 号:T79144产 地:中国大陆
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T79079JAK1-IN-11;化合物 JAK1-IN-11JAK1-IN-11
JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations with IC50 values of 0.02 nM (JAK1) and 0.44 nM (JAK2), demonstrating high selectivity for JAK1 over JAK2 [1].
价 格:¥电议型 号:T79079产 地:中国大陆
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T79078JAK1-IN-10;化合物 JAK1-IN-10JAK1-IN-10
JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor of JAK1 [1].
价 格:¥电议型 号:T79078产 地:中国大陆
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T79071HPK1 antagonist-1;化合物 HPK1 antagonist-1HPK1 antagonist-1
HPK1 antagonist-1 (I-792) is an inhibitor targeting HPK1, with potential applications in cancer and immune disease research [1].
价 格:¥电议型 号:T79071产 地:中国大陆
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T7897PK150;化合物PK150PK150
PK150 shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations.
价 格:¥电议型 号:T7897产 地:中国大陆
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T78852HPK1-IN-39;化合物 HPK1-IN-39HPK1-IN-39
HPK1-IN-39 (Compound 10n), a selective inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) with an inhibitory concentration (IC50) of 29 nM, impedes the phosphorylation of SLP76. This compound is applicable in the research of cancer immunotherapy [1].
价 格:¥电议型 号:T78852产 地:中国大陆
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T78688HPK1-IN-35;化合物 HPK1-IN-35HPK1-IN-35
HPK1-IN-35 is a potent, selective inhibitor of HPK1, demonstrating an IC50 value of 3.5 nM. This compound reduces p-SLP76 expression and facilitates the secretion of IL-2 [1].
价 格:¥电议型 号:T78688产 地:中国大陆
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T78605CpCDPK1/TgCDPK1-IN-1;CpCDPK1/TgCDPK1抑制剂1CpCDPK1/TgCDPK1-IN-1
CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections and cryptosporidiosis.
价 格:¥电议型 号:T78605产 地:中国大陆
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T78425GK16S;化合物 GK16SGK16S
GK16S, a UCHL1 chemogenomic probe, serves as a complementary tool to GK13S for the investigation of UCHL1 function in cellular studies [1].
价 格:¥电议型 号:T78425产 地:中国大陆
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T78268Anti-Mouse NK1.1 Antibody (PK136);化合物 Anti-Mouse NK1.1 Antibody (PK136)Anti-Mouse NK1.1 Antibody (PK
Anti-Mouse NK1.1 Antibody (PK136) is an IgG2a class antibody of murine origin targeting NK1.1, which eliminates NK1.1 and NK1.1NKT cells and inhibits NK1.1 signaling in peripheral blood, spleen, and lung tissues, and can be used in the study of heart and lung failure.
价 格:¥电议型 号:T78268产 地:中国大陆
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T78190ERK1/2 inhibitor 9;化合物 ERK1/2 inhibitor 9ERK1/2 inhibitor 9
ERK1/2 Inhibitor 9 (Probe 1), a covalent antagonist of ERK1/2, exhibits sub-micromolar efficacy in cellular assays (A375 GI50=0.47 μM) and facilitates the reduction of phospho-ERK1/2 levels. When conjugated with trans-cyclo-octene (TCO) and Tz-Thalidomide (tetrazine-tagged Thalidomide), it forms the corresponding ERK-CLIPTAC, promoting targeted ERK1/2 degradation [1].
价 格:¥电议型 号:T78190产 地:中国大陆
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T78128GALK1-IN-1;化合物 GALK1-IN-1GALK1-IN-1
Compound 4, known as GALK1-IN-1, is a potent inhibitor of galactokinase, exhibiting an IC50 value of 4.2129 μM [1].
价 格:¥电议型 号:T78128产 地:中国大陆
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T78035[K15,R16,L27]VIP(1-7)/GRF(8-27) acetate;化合物 [K15,R16,L27]VIP(1-7)/GRF(8-27) acetate[K15,R16,L27]VIP(
[K15,R16,L27]VIP(1-7)/GRF(8-27) (acetate) is an acetate salt form of the peptide [K15,R16,L27]VIP(1-7)/GRF(8-27). This compound acts as a selective agonist for the VIP 1 receptor, displaying IC50 values of 2 nM for human VIP 1, 1 nM for rat VIP 1, and 30,000 nM for rat VIP 2 receptors [1]. The peptide´s acronym, VIP, stands for Vasoactive Intestinal Polypeptide.
价 格:¥电议型 号:T78035产 地:中国大陆
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T77504JAK1/2/3 Inhibitor 1;化合物 JAK1/2/3 Inhibitor 1JAK1/2/3 Inhibitor 1
JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell lines. It inhibits the growth of cancer cells by binding to the cancer cell backbone and inhibiting the production of new proteins.
价 格:¥电议型 号:T77504产 地:中国大陆
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T76668FC382K10W15 TFA;化合物 FC382K10W15 TFAFC382K10W15 TFA
FC382K10W15 TFA, a glucagon analogue and GLP-1R/GCGR agonist, holds promise for research in type 2 diabetes [1].
价 格:¥电议型 号:T76668产 地:中国大陆
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T76557Myristoyl-MEK1 Derived Peptide Inhibitor 1;化合物 Myristoyl-MEK1 Derived Peptide Inhibitor 1Myristoyl-M
Myristoyl-MEK1 Derived Peptide Inhibitor 1, the myristoylated variant of MEK1 Derived Peptide Inhibitor 1, effectively inhibits ERK activation, demonstrating an inhibitory concentration (IC50) of 10 μM [1].
价 格:¥电议型 号:T76557产 地:中国大陆