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T16811RWJ-51204;化合物RWJ-51204RWJ-51204
RWJ-51204 is a selective adenosine A2A receptor antagonist and a partial agonist of GABA(A) receptor (IC50: 0.2-2 nM). It has neuroprotective and movement-improving effects and can be used in research related to Parkinson´s disease.
价 格:¥电议型 号:T16811产 地:中国大陆
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T16407Osajin化合物 T16407NSC 21565|||CID 95168
Osajin is the major bioactive iso avone present in the fruit of Maclura pomifera. It has antitumor, antioxidant, and anti-inflammatory activities.
价 格:¥电议型 号:T16407产 地:中国大陆
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T16364Infigratinib phosphate;磷酸英非替尼NVP-BGJ398 phosphate|||BGJ-398 phosphate;NVP-BGJ398 phosphate|||BGJ-398
Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).
价 格:¥电议型 号:T16364产 地:中国大陆
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T16022Arhalofenate;芳卤芬酯JNJ 39659100|||MBX 102;JNJ 39659100|||芳卤芬酯|||4-氯-ALPHA-[3-(三氟甲基)苯氧基]苯乙酸 2-(乙酰基氨基)乙酯
Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.
价 格:¥电议型 号:T16022产 地:中国大陆
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T15777Loxoribine;洛索立宾RWJ 21757|||7-Allyl-8-oxoguanosine;RWJ 21757|||7-Allyl-8-oxoguanosine|||洛索立宾
Loxoribine (RWJ 21757) is a guanosine analog. Loxoribine is an orally bioavailable and selective Toll-like receptor (TLR) 7 agonist. It has anti-viral and anti-tumor activities.Loxoribine is a potent new immunostimulant with a relatively broad spectrum of immunobiological activities.
价 格:¥电议型 号:T15777产 地:中国大陆
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T15665KJ Pyr 9;化合物KJ Pyr 9KJ Pyr 9
KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).
价 格:¥电议型 号:T15665产 地:中国大陆
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T15635JZP-430;化合物JZP-430JZP-430
JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).
价 格:¥电议型 号:T15635产 地:中国大陆
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T15634JYL 1421化合物JYL 1421SC 0030
JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).
价 格:¥电议型 号:T15634产 地:中国大陆
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T15633JW74;化合物JW74JW74
JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).
价 格:¥电议型 号:T15633产 地:中国大陆
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T15632JW 642;化合物JW 642JW 642
JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).
价 格:¥电议型 号:T15632产 地:中国大陆
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T15631JTK-853;化合物 T15631JTK-853
JTK-853 is a novel, non-nucleoside inhibitor of Hepatitis C Virus (HCV) polymerase. It also displays effective antiviral activity in HCV replicon cells (EC50s: 0.38 and 0.035 μM in genotype 1a H77 and 1b Con1 strains, respectively).
价 格:¥电议型 号:T15631产 地:中国大陆
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T15630Tilmacoxib;替马考昔RWJ57504|||JTP19605|||JTE522;RWJ57504|||JTP19605|||替马考昔|||JTE522
Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).
价 格:¥电议型 号:T15630产 地:中国大陆
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T15629JTE-013;化合物JTE-013JTE-013
JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively).
价 格:¥电议型 号:T15629产 地:中国大陆
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T15628JT010;化合物JT010JT010
JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).
价 格:¥电议型 号:T15628产 地:中国大陆
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T15627(S)-JQ-35化合物 T15627TEN-010
(S)-JQ-35 (TEN-010) is an inhibitor of the Bromodomain and Extra-Terminal (BET) family bromodomain-containing proteins. It has a potential antineoplastic activity.
价 格:¥电议型 号:T15627产 地:中国大陆
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T15626JPM-OEt;化合物 T15626JPM-OEt
JPM-OEt is a broad spectrum cysteine cathepsin inhibitor with antitumor activity. JPM-OEt binds covalently in the active site and irreversibly inhibits the cysteine cathepsin family.
价 格:¥电议型 号:T15626产 地:中国大陆
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T15625JNJ4796;化合物 T15625JNJ4796
JNJ4796 is an oral active fusion inhibitor of the influenza virus, by inhibiting hemagglutinin (HA)-mediated fusion to neutralizing the influenza A group 1 virus. JNJ4796 mimics the functionality of the broadly neutralizing antibodies (bnAbs).
价 格:¥电议型 号:T15625产 地:中国大陆
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T15624JNJ-64619178;化合物JNJ-64619178JNJ-64619178
JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer.
价 格:¥电议型 号:T15624产 地:中国大陆
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T15623JNJ-61432059;化合物JNJ-61432059JNJ-61432059
JNJ-61432059 is an oral active and selective negative modulator of TARP γ?8 Selective AMPAR(pIC50: 9.7).
价 格:¥电议型 号:T15623产 地:中国大陆
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T15622JNJ-54175446;化合物 JNJ-54175446JNJ-5446;JNJ-5446
JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1β/IL-18 from microglia, and may be used in the study of depression.
价 格:¥电议型 号:T15622产 地:中国大陆