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T81600Oregon-BAPTA Green 1AM;化合物 Oregon-BAPTA Green 1AMOregon Green 488 BAPTA 1AM;Oregon Green 488 BAPTA 1
Oregon-BAPTA Green 1AM (Oregon Green 488 BAPTA 1AM) is a fluorescent calcium (Ca 2+) indicator, comprising a green fluorescent probe, OG 488, and a cell-permeable calcium chelator, BAPTA AM.
价 格:¥电议型 号:T81600产 地:中国大陆
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T81309RCB16007;化合物 RCB16007RCB16007
RCB16007 is a Yellow Fever Virus (YFV) inhibitor that also demonstrates inhibitory action against the West Nile virus with an effective concentration (EC50) of 7.9 μM and a cytotoxic concentration (CC50) of 17 μM [1].
价 格:¥电议型 号:T81309产 地:中国大陆
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T81025Teduglutide TFA;化合物 Teduglutide TFAALX-0600 TFA;ALX-0600 TFA
Teduglutide TFA, a dipeptidyl peptidase IV-resistant glucagon-like peptide-2 (GLP-2) analogue, exhibits trophic effects on the gut mucosa and is used in research related to short bowel syndrome (SBS) and Crohn´s disease (CD) [1] [2].
价 格:¥电议型 号:T81025产 地:中国大陆
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T80816WAY-329600;化合物 WAY-329600WAY-329600
WAY-329600 is an active molecule.
价 格:¥电议型 号:T80816产 地:中国大陆
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T80600Peginterferon lambda-1a;化合物 Peginterferon lambda-1aBMS-914143;BMS-914143
Peginterferon lambda-1a (BMS-914143) is a monoclonal antibody that targets IFNLR1 and is composed of IFNL1 conjugated to pegol [1].
价 格:¥电议型 号:T80600产 地:中国大陆
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T79908ON 108600;化合物 ON 108600ON 108600
ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.028 μM for DYRK2, 0.05 μM and 0.005 μM for CK2α1 and CK2α2, and 0.005 μM for TNIK, respectively. This compound exhibits antitumor activity [1].
价 格:¥电议型 号:T79908产 地:中国大陆
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T79784VU6004909;化合物 VU6004909VU6004909
VU6004909 is a positive allosteric modulator of the mGlu5 receptor (pEC50: 7.59), exhibiting antipsychotic-like effects. It has the capability to reverse MK801-induced cortical hyperactivity and cognitive deficits [1] [2].
价 格:¥电议型 号:T79784产 地:中国大陆
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T79600Zharp2-1;化合物 Zharp2-1Zharp2-1
Zharp2-1, a RIPK2 inhibitor, inhibits the transcription of inflammatory cytokines induced by MDP-induced or Listeria monocytogenes infection and alleviates MDP-induced peritonitis symptoms in mice, which can be used for the study of inflammatory bowel disease (IBD).
价 格:¥电议型 号:T79600产 地:中国大陆
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T78850EGFR/BRAFV600E-IN-3;化合物 EGFR/BRAFV600E-IN-3EGFR/BRAFV600E-IN-3
EGFR/BRAFV600E-IN-3 is an inhibitor targeting EGFR, BRAFV600E, and EGFRT790M with IC50 values of 57 nM, 68 nM, and 9.70 nM, respectively. It induces apoptosis and exhibits promising antioxidant activity [1].
价 格:¥电议型 号:T78850产 地:中国大陆
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T78849EGFR/BRAFV600E-IN-2;化合物 EGFR/BRAFV600E-IN-2EGFR/BRAFV600E-IN-2
E07 Aptamer, targeting the human epidermal growth factor receptor (hEGFR), competes with epidermal growth factor (EGF) for binding to a unique epitope on EGFR. This aptamer not only binds to EGFR-expressing cells but also inhibits receptor autophosphorylation and thwarts tumor cell proliferation in three-dimensional matrices, positioning it as a useful tool for tumor disease research [1].
价 格:¥电议型 号:T78849产 地:中国大陆
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T78600VU0029251;化合物 VU0029251VU0029251
VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM. It also attenuates glutamate-induced calcium mobilization in HEK293 cell membranes that express rat mGluR5, demonstrating an IC 50 of 1.7 μM [1].
价 格:¥电议型 号:T78600产 地:中国大陆
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T78295Samalizumab;沙马组单抗ALXN 6000;ALXN 6000
Samalizumab (ALXN 6000), a humanized monoclonal antibody, selectively targets and inhibits the interaction between CD200 and its receptor (CD200R). This compound is utilized in the research of multiple myeloma and B-cell chronic lymphocytic leukemia [1].
价 格:¥电议型 号:T78295产 地:中国大陆
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T77600Methyl-4-oxoretinoate;化合物Methyl-4-oxoretinoateMethyl-4-oxoretinoate
Methyl-4-oxoretinoate is a synthetic retinoid compound with anticancer compounds that can induce differentiation and apoptosis in cancer cells.Methyl-4-oxoretinoate is used in the treatment of acne, psoriasis, and other skin disorders.Methyl-4-oxoretinoate has the potential to be used in the treatment of a variety of ocular disorders such as age-related macular degeneration. related macular degeneration).
价 格:¥电议型 号:T77600产 地:中国大陆
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T76600Ac-Trp-Glu-His-Asp-Aldehyde;化合物 Ac-Trp-Glu-His-Asp-AldehydeAc-Trp-Glu-His-Asp-Aldehyde
Ac-Trp-Glu-His-Asp-Aldehyde is a powerful and selective inhibitor of caspase-1, demonstrating a K_i value of 56 pM [1] [2].
价 格:¥电议型 号:T76600产 地:中国大陆
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T76009Thermolysin;化合物 ThermolysinThermolysin
Thermolysin, a thermostable neutral metalloproteinase enzyme secreted by the Gram-positive bacterium Bacillus thermoproteolyticus, catalyzes the hydrolysis of peptide bonds containing hydrophobic residues [1].
价 格:¥电议型 号:T76009产 地:中国大陆
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T76008Protein Kinase C (19-31) (TFA);化合物 Protein Kinase C (19-31) (TFA)Protein Kinase C (19-31) (TFA)
Protein Kinase C (19-31) TFA is a peptide inhibitor derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), featuring a serine substitution for alanine at position 25. It serves as a substrate peptide for evaluating Protein Kinase C (PKC) activity. PKC TFA plays a crucial role in modulating protein functions by phosphorylating the hydroxyl groups of serine and threonine amino acids on target proteins [1] [2].
价 格:¥电议型 号:T76008产 地:中国大陆
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T76007RGD peptide (GRGDNP) (TFA);化合物 RGD peptide (GRGDNP) (TFA)RGD peptide (GRGDNP) (TFA)
RGD peptide (GRGDNP) TFA functions as an inhibitor of integrin-ligand interactions, competitively blocking α5β1´s interaction with the extracellular matrix (ECM). It induces apoptosis by triggering conformational changes that facilitate pro-caspase-3 activation and autoprocessing. Furthermore, RGD peptide (GRGDNP) TFA is critical in regulating cell adhesion, migration, growth, and differentiation [1] [2] [3].
价 格:¥电议型 号:T76007产 地:中国大陆
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T76006Tirzepatide TFA;化合物 Tirzepatide TFATirzepatide TFA(2023788-19-2 free base)|||LY3298176 TFA;Tirzepati
Tirzepatide TFA (LY3298176 TFA), a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, is under development for type 2 diabetes treatment [1].
价 格:¥电议型 号:T76006产 地:中国大陆
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T76005LSuper-TDU (1-31) (TFA);化合物 Super-TDU (1-31) (TFA)Super-TDU (1-31) (TFA)
Super-TDU (1-31) TFA, a peptide fragment of Super-TDU, acts as an inhibitor of the YAP-TEAD complex. Demonstrating potent anti-tumor activity, it effectively suppresses tumor growth in a gastric cancer mouse model [1] [2].
价 格:¥电议型 号:T76005L产 地:中国大陆
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T76005Super-TDU (1-31);化合物 Super-TDU (1-31)Super-TDU (1-31)
Super-TDU (1-31), a peptide fragment of Super-TDU, acts as an inhibitor of the YAP-TEAD complex. Demonstrating potent anti-tumor activity, it effectively suppresses tumor growth in a gastric cancer mouse model [1] [2].
价 格:¥电议型 号:T76005产 地:中国大陆