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T6841FumagillinFumagillin,NSC 9168,Antibiotic,inhibit,Human immunodeficiency virus,Parasite,Inhibitor,NSC
Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
价 格：￥电议型 号：T6841产 地：中国大陆
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T8930CID44216842diseases,neutrophils,ovarian,disorders,Cdc42,fibroblasts,breast,hepatitis C,CID 44216842,
CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.
价 格：￥电议型 号：T8930产 地：中国大陆
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T16845Sarolanerdog,Sarolaner,Parasite,PF 6450567,flea,Inhibitor,oral,inhibit,isoxazoline,tick,PF6450567
Sarolaner is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).
价 格：￥电议型 号：T16845产 地：中国大陆
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TN6848Piperonylic acidformation,virus,natural,inactivator,Cytochrome P450,Piperonylic acid,quasi-irreversi
Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic acid selectively inactivate the CYP73A P450 subpopulation.
价 格：￥电议型 号：TN6848产 地：中国大陆
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T6845GNE-317inhibit,GNE-317,Inhibitor,Phosphoinositide 3-kinase,Mammalian target of Rapamycin,mTOR,GNE 31
GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).
价 格：￥电议型 号：T6845产 地：中国大陆
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T6848GSK1016790Ainhibit,Ca2+ channels,Inhibitor,embryonic,GSK-1016790A,Ca channels,HEK,vanilloid,transien
GSK1016790A (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells.
价 格：￥电议型 号：T6848产 地：中国大陆
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T8517BelinostatHistone deacetylases,PX-105684,PX 105684,Inhibitor,HDAC,Belinostat,PXD 101,inhibit,Autopha
Belinostat is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.
价 格：￥电议型 号：T8517产 地：中国大陆
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T8684SotorasibAMG 510,Ras,KRAS,covalent,Sotorasib,regression,mutation,Inhibitor,G12C,anti-tumour,inhibit,
AMG-510 is a selective and orally bioavailable KRAS G12C covalent inhibitor.
价 格：￥电议型 号：T8684产 地：中国大陆
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T16491PF-06446846 hydrochloridePF06446846 hydrochloride,PF 06446846 hydrochloride
PF-06446846 hydrochloride suppresses PCSK9 by inducing the ribosome to stall around codon 34. PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9.
价 格：￥电议型 号：T16491产 地：中国大陆
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T6847GSK-J1GSK-J1,inhibit,Inhibitor,Histone Demethylase,GSKJ1,GSK-J-1
GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.
价 格：￥电议型 号：T6847产 地：中国大陆
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T6843GDC-0623Mitogen-activated protein kinase kinase,Apoptosis,inhibit,MEK,Inhibitor,MAP2K,MAPKK,MEK inhi
GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
价 格：￥电议型 号：T6843产 地：中国大陆
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TN1684Ginsenoside F5Ginsenoside F-5,inhibit,Ginsenoside F5,leukemia,Ginsenoside F 5,Inhibitor,Apoptosis,pr
Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway
价 格：￥电议型 号：TN1684产 地：中国大陆
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T12684Radioprotectin-1
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
价 格：￥电议型 号：T12684产 地：中国大陆
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T6846VesatolimodHepatitis B virus,Vesatolimod,HCV,inhibit,Apoptosis,GS9620,Human immunodeficiency virus,G
GS-9620 is an effective and specific orally active agonist of Toll-like receptor 7.
价 格：￥电议型 号：T6846产 地：中国大陆
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T8645PF-06446846Threonine proteases,PF06446846,Inhibitor,80S ribosome,Selective,PF 06446846,Ser/Thr Prote
PF 06446846 is a potent and selective PCSK9 inhibitor
价 格：￥电议型 号：T8645产 地：中国大陆
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T6849UprosertibGSK-2141795,GSK 2141795,Uprosertib,inhibit,Akt,Inhibitor,PKB,Protein kinase B
Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.
价 格：￥电议型 号：T6849产 地：中国大陆
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T6840FRAX486PAK,p21 activated kinases,FRAX 486,Inhibitor,FRAX-486,inhibit,FRAX486
FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
价 格：￥电议型 号：T6840产 地：中国大陆
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T6842G007-LKG007LK,Inhibitor,poly ADP ribose polymerase,G-007-LK,G007 LK,PARP,inhibit,G007-LK
G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.
价 格：￥电议型 号：T6842产 地：中国大陆
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T6840LFRAX486 HCL(1232030-35-1 free base)FRAX486 HCL(1232030351 free base),FRAX486 HCL(1232030 35 1 free b
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
价 格：￥电议型 号：T6840L产 地：中国大陆
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T6S16848-GingerolInhibitor,8Gingerol,Transient receptor potential channels,8 Gingerol,TRP Channel,inhibit,8
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristics. 5. 8-Gingerol seems to be effective in an animal model of rheumatoid arthritis. 6. 8-Gingerol inhibits the anti-serotonin 3 receptor function, exhibits cardiotonic activity. 7. 8-Gingerol affects gastric motility and potentially have an antispasmodic effect on the gastrointest
价 格：￥电议型 号：T6S1684产 地：中国大陆
