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产品数:86101
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T7529Yamogenintriacylglyceride,Inhibitor,fatty acid synthesis,Diastereomer,Yamogenin,Liver X receptor,LXR
Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.
价 格:¥电议型 号:T7529产 地:中国大陆
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T7833TLX agonist 1TLX agonist-1,transcriptional,TLX agonist 1,repressive,Inhibitor,ligand,inhibit,TLX ago
TLX agonist 1 is an orphan nuclear receptor tailless (TLX, NR2E1) modulator
价 格:¥电议型 号:T7833产 地:中国大陆
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TQ027427-Hydroxycholesterol27Hydroxycholesterol,LXR,Liver X receptor,Inhibitor,Estrogen Receptor/ERR,Endog
27-Hydroxycholesterol is a selective modulator of estrogen receptor and an agonist of the liver X receptor.
价 格:¥电议型 号:TQ0274产 地:中国大陆
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T8750LX-4211 intermediateLX 4211 intermediate,LX4211 intermediate
LX-4211 intermediate a chemical compound.
价 格:¥电议型 号:T8750产 地:中国大陆
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TP1364LALX 40-4C acetateALX 404C acetate,ALX 40 4C acetate
ALX 40-4C acetate is a CXCR4 inhibitor of the chemokine receptor (Ki = 1 μM) and suppresses the replication of X4 strains of HIV-1. ALX 40-4C acetate is an antagonist of the APJ receptor (IC50 = 2.9 μM).
价 格:¥电议型 号:TP1364L产 地:中国大陆
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T7768RGX-104RGX 104,inhibit,LXR,RGX-104,Liver X receptor,RGX104,Inhibitor
RGX-104 free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR)
价 格:¥电议型 号:T7768产 地:中国大陆
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T38622Bcl-xL antagonist 2Bcl xL antagonist 2,BclxL antagonist 2
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic leukemia and non-Hodgkin’s lymphoma.
价 格:¥电议型 号:T38622产 地:中国大陆
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T8654Plx-4032Plx 4032,Plx4032
PLX-4032 is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.
价 格:¥电议型 号:T8654产 地:中国大陆
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T12262L1NPS ALX Compound 4a hydrochloride(1:1)NPSALXCompound4ahydrochloride(299433106Freebase)
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.
价 格:¥电议型 号:T12262L1产 地:中国大陆
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T39214LLXE408 fumarate
LXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective?proteasome?inhibitor. LXE408 fumarate has an?IC50?of 0.04 μM for?L. donovani?proteasome and an?EC50?of 0.04 μM for?L. donovani. LXE408 fumarate has a low propensity to cross the blood brain barrier. LXE408 fumarate has the potential for visceral leishmaniasis (VL) research.
价 格:¥电议型 号:T39214L产 地:中国大陆
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T8753LX-2761 intermediateLX 2761 intermediate,LX2761 intermediate
LX-2761 intermediate a chemical compound.
价 格:¥电议型 号:T8753产 地:中国大陆
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T6690T0901317orally,fibroblasts,FXR,LXRβ,T0901317,foreskin,T 0901317,Liver X receptor,atherosclerosis,LDL
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).
价 格:¥电议型 号:T6690产 地:中国大陆
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TQ0253PLX51107PLX 51107,Epigenetic Reader Domain,PLX51107,inhibit,PLX-51107,Inhibitor
PLX51107 is a potent and selective BET inhibitor (Kds: 1.6, 2.1, 1.7, and 5 nM for BRD2-BD1, BRD3-BD1, BRD4-BD1, and BRDT-BD1).
价 格:¥电议型 号:TQ0253产 地:中国大陆
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TP1474LXW7LXW7,Integrin,Anti-inflammatory,Inhibitor,LXW-7,ERK1/2,VEGFR-2,LXW 7,αvβ3,inhibit
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-peptide (cGRGDdvc) containing unnatural amino acids flanking both sides of the main functional motif.
价 格:¥电议型 号:TP1474产 地:中国大陆
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T7100PLX5622PLX5622,PLX 5622,Inhibitor,CSF-1 receptor,microglial,CSF1R,orally,pathology,inhibit,c-Fms,pen
PLX-5622 is a highly selective brain penetrant and oral active CSF1R inhibitor.
价 格:¥电议型 号:T7100产 地:中国大陆
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T8500VLX600iron,HCT116,Autophagy,glycolytic,VLX 600,colon,chelator,cancer,OXPHOS,VLX600,Mitochondrial Met
VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells.
价 格:¥电议型 号:T8500产 地:中国大陆
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T62929RLX-33
RLX-33 is a potent, selective and blood-brain barrier (BBB) penetrant antagonist of relaxin family peptide 3 (RXFP3, IC50=2.36 μM). RLX-33 also blocks relaxin-3-induced ERK1/2 phosphorylation, with IC50s of 7.82 and 13.86 μM for ERK1 and ERK2 phosphorylation, respectively. RLX-33 can inhibits the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats.
价 格:¥电议型 号:T62929产 地:中国大陆
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T7281F-15599NLX-101,inhibit,5-HT Receptor,Serotonin Receptor,NLX 101,F-15599,NLX101,F15599,F 15599,5-hydr
F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).
价 格:¥电议型 号:T7281产 地:中国大陆
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T8107GLX351322GLX351322,GLX-351322,GLX 351322,NADPH Oxidase,NOX,Inhibitor,inhibit
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
价 格:¥电议型 号:T8107产 地:中国大陆
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T13355XanthorrhizolXanthorrhizol,inhibit,Bacterial,Inhibitor
Xanthorrhizol is a natural product isolated from Curcuma xanthorrhiza Roxb. Xanthorrhizol is a potential antibacterial agent.
价 格:¥电议型 号:T13355产 地:中国大陆