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  • T36809UoS 12258UoS 12258UoS 12258

    Positive allosteric modulator of AMPA receptors (pEC50 = 5.2 for potentiation of AMPA-mediated currents in vitro). Also potentiates AMPA-mediated synaptic responses in vivo. Improves performance of rats in various learning and memory paradigms

    价 格：￥电议型 号：T36809产 地：中国大陆

  • T36758CAIX Inhibitor S4；化合物CAIX Inhibitor S4S4；S4

    CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM.

    价 格：￥电议型 号：T36758产 地：中国大陆

  • T36658Boc-Glu-OBzl；Boc-Glu-OBzlBoc-Glu-OBzl

    Boc-Glu-OBzl is an amino acid building block.1,2It has been used in the synthesis of peptide-based inhibitors of human caspases and human rhinovirus (HRV) 3C protease that have enzyme inhibitory activityin vitro.

    价 格：￥电议型 号：T36658产 地：中国大陆

  • T365889(R)-PAHSA；9(R)-PAHSA9(R)-PAHSA

    9(R)-PAHSA is a stereoisomer of 9-PAHSA , an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).

    价 格：￥电议型 号：T36588产 地：中国大陆

  • T36587APTS；化合物 APTS8-Aminopyrene-1,3,6-trisulfonic acid trisodium；8-Aminopyrene-1,3,6-trisulfonic acid tri

    8-Aminopyrene-1,3,6-trisulfonic Acid (sodium salt) is an anionic fluorescent dye used as a reporter for glucose sensing and for the detection of other saccharides. The excitation/emission spectra is 425/503 nm. 8-Aminopyrene-1,3,6-trisulfonic Acid (sodium salt) can be used in solution or immobilized through attachment of an aldehyde functionalized monomer by reductive amination without significantly changing fluorescence intensity.

    价 格：￥电议型 号：T36587产 地：中国大陆

  • T3658612-PAHSA；12-PAHSA12-PAHSA

    Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 12-PAHSA is a FAHFA in which palmitic acid is esterified at the 12th carbon of hydroxy stearic acid. Among the FAHFA family members, PAHSAs ar

    价 格：￥电议型 号：T36586产 地：中国大陆

  • T36585Isodeoxycholic Acid；异脱氧胆酸isoDCA；isoDCA

    Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less active than DCA in inhibiting growth in a panel of seven gut commensal bacteria species. Isodeoxycholic Acid(0.1%) inhibits spore germination induced by taurocholic acid in several C. difficile strains, as well as decreases the cytotoxicity of C. difficile culture supernatants t

    价 格：￥电议型 号：T36585产 地：中国大陆

  • T36583Gly-Pro-pNA hydrochloride；Gly-Pro-pNA盐酸盐Gly-Pro p-nitroanilide hydrochloride；Gly-Pro p-nitroanilide

    Gly-Pro-pNA hydrochloride (Gly-Pro p-nitroanilide hydrochloride) is a dipeptidyl peptidase inhibitor that inhibits dipeptidyl peptidase II, dipeptidyl peptidase IV and dipeptidyl peptidase IX.

    价 格：￥电议型 号：T36583产 地：中国大陆

  • T36581Glucocerebrosides；葡萄糖脑苷Glucocerebrosides

    Glucocerebrosides is a natural product.

    价 格：￥电议型 号：T36581产 地：中国大陆

  • T36580Glucagon Receptor Antagonist Inactive Control；Glucagon Receptor Antagonist Inactive ControlGlucagon

    Glucagon Receptor Antagonist Inactive Control is a Glucagon receptor antagonist that can be used in related research in the field of life sciences. Its product number is T36580 and CAS number is 362482-00-6.

    价 格：￥电议型 号：T36580产 地：中国大陆

  • T3658Trifluridine/tipiracil hydrochloride mixture；化合物TAS102Trifluridine-tipiracil hydrochloride mixture||

    Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 2:1.

    价 格：￥电议型 号：T3658产 地：中国大陆

  • T36558(±)9-HETE；(±)9-HETE(±)9-HETE

    (±)9-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPLC. The racemic HETEs have been quantified as an index of lipid peroxidation using GC/MS.

    价 格：￥电议型 号：T36558产 地：中国大陆

  • T3651YM-58483；化合物YM58483YM 58483|||BTP2；YM 58483|||BTP2

    YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals.

    价 格：￥电议型 号：T3651产 地：中国大陆

  • T36458CAY10701；CAY10701CAY10701；CAY10701

    CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively). It also inhibits the growth of several different colorectal cancer cell lines (GI50 values range from 9 to 17 nM), while being at least 1,500-fold less effective against normal human fibroblast WI38 cells. CAY10701 is effective in vivo, reducing tumor volume in colorectal cell xenografts in mice without significantly altering body

    价 格：￥电议型 号：T36458产 地：中国大陆

  • T36358Diminutol；DiminutolDiminutol

    Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.

    价 格：￥电议型 号：T36358产 地：中国大陆

  • T3628Madrasin；化合物MadrasinDDD00107587；DDD00107587

    Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.

    价 格：￥电议型 号：T3628产 地：中国大陆

  • T36201LAZD5582 TFA；AZD5582 三氟乙酸盐AZD5582 TFA（1258392-53-8 free base）；AZD5582 TFA（1258392-53-8 free ba

    AZD5582 TFA is a potent IAP antagonist that binds to the BIR3 domain of cIAP1, cIAP2, and XIAP with IC50 values of 15, 21, and 15 nM, respectively.AZD5582 TFA induces apoptosis.

    价 格：￥电议型 号：T36201L产 地：中国大陆

  • T36201AZD5582 dihydrochloride；AZD 5582 dihydrochlorideAZD 5582 dihydrochloride；AZD 5582 dihydrochloride

    Dimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively). Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9. Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells. Causes tumor regression in MDA-MB-231 xenograft-bearing mice.

    价 格：￥电议型 号：T36201产 地：中国大陆

  • T3620Solcitinib；索西替尼GLPG-0778|||GSK-2586184；索西替尼|||GLPG-0778|||GSK-2586184

    Solcitinib (GLPG-0778) (GSK2586184, GLPG0778) is a JAK1 inhibitor. Solcitinib may be potentially used for the treatment of psoriasis, ulcerative colitis, and systemic lupus erythematosus.

    价 格：￥电议型 号：T3620产 地：中国大陆

  • T361588-iso Prostaglandin A2；8-iso Prostaglandin A28-iso Prostaglandin A2；8-iso Prostaglandin A2

    8-iso Prostaglandin A2 is an isoprostane produced by the nonenzymatic oxidation of arachidonic acid.

    价 格：￥电议型 号：T36158产 地：中国大陆

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