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  • T3586Compound 401;化合物Compound 4012-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one;2-morpholino-4H-pyrimid

    Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.

    价 格:¥电议型 号:T3586产 地:中国大陆

  • T35859Aldumastat;化合物 AldumastatGLPG1972|||S201086|||G504572;GLPG1972|||S201086|||G504572

    Aldumastat (GLPG1972) is a highly potent, specific and orally active inhibitor of ADAMTS-5.Aldumastat is used for the study of osteoarthritis of the knee.

    价 格:¥电议型 号:T35859产 地:中国大陆

  • T35858Adrenomedullin (22-52) (human) (trifluoroacetate salt);Adrenomedullin (22-52) (human) (trifluoroacet

    Adrenomedullin (22-52) is a C-terminal fragment of adrenomedullin (1-52) .

    价 格:¥电议型 号:T35858产 地:中国大陆

  • T35857Actinopyrone A;Actinopyrone AActinopyrone A

    Actinopyrone A is a pyrone isolated from S. pactum with diverse biological activities. It has selective and potent antimicrobial activity against H. pylori (MIC = 0.1 ng/mL) with no activity against other Gram-negative bacteria including E. coli, K. pneumoniae, P. aeruginosa, and B. fragilis. Actinopyrone A also mildly inhibits growth of Gram-positive bacteria and dermatophytes with MIC values ranging from <6.25 to 25 μg/mL. Intravenous administration of actinopyrone A (30 μg/kg) increases coron

    价 格:¥电议型 号:T35857产 地:中国大陆

  • T35856BMS-986176;化合物BMS-986176BMS-986176

    AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).

    价 格:¥电议型 号:T35856产 地:中国大陆

  • T35855AAA;AAAAAA

    AAA is an antagonist of G protein-coupled receptor 75 (GPR75).1It increases basal GPR75 protein levels and inhibits 20-HETE-induced reductions in GPR75 protein levels in PC3 cells. AAA (5 and 10 μM) also reduces 20-HETE-induced phosphorylation of EGFR, NF-κB, and Akt in, and cell migration of, PC3 cells.

    价 格:¥电议型 号:T35855产 地:中国大陆

  • T358549(Z),11(E)-Conjugated Linoleic Acid (sodium salt);9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)9

    9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-co

    价 格:¥电议型 号:T35854产 地:中国大陆

  • T358539(S)-HODE cholesteryl ester;9(S)-HODE cholesteryl ester9(S)-HODE cholesteryl ester

    9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 9(S)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.

    价 格:¥电议型 号:T35853产 地:中国大陆

  • T35852FAPI-34;FAPI-34FAPI-34

    FAPI-34, a fibroblast-activating protein (FAP) inhibitor, boasts advantageous pharmacokinetic and biochemical attributes.

    价 格:¥电议型 号:T35852产 地:中国大陆

  • T35851Etzadroxil;2-乙基丁酸乙酯Ethyl 2-Ethylbutyrate;Ethyl 2-Ethylbutyrate

    Etzadroxil (Ethyl 2-Ethylbutyrate) is an orally available and volatile esterification.Etzadroxil has broad-spectrum antimicrobial activity for the treatment of urinary tract infections caused by multi-drug resistant bacteria.

    价 格:¥电议型 号:T35851产 地:中国大陆

  • T3585019(S)-HETE;19(S)-HETE19(S)-HETE

    19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. 19(S)-HETE stimulates both renal sodium-potassium ATPase and volume absorption in the rabbit proximal straight tubule.

    价 格:¥电议型 号:T35850产 地:中国大陆

  • T3584917(S)-HETE;17(S)-HETE17(S)-HETE

    Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney.17(S)-HETE inhibits proximal tubule ATPase activity by as much as 70% at a concentration of 2 μM.

    价 格:¥电议型 号:T35849产 地:中国大陆

  • T3584816(S)-HETE;16(S)-HETE16(S)-HETE

    Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase activity by as much as 60% at a concentration of 2 μM.

    价 格:¥电议型 号:T35848产 地:中国大陆

  • T3584716(R)-HETE;16(R)-HETE16(R)-HETE

    Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that

    价 格:¥电议型 号:T35847产 地:中国大陆

  • T3584613(R)-HODE cholesteryl ester;13(R)-HODE cholesteryl ester13(R)-HODE cholesteryl ester

    13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 13(R)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.

    价 格:¥电议型 号:T35846产 地:中国大陆

  • T35845(R,S)-Carvedilol Glucuronide;(R,S)-Carvedilol Glucuronide(R,S)-Carvedilol Glucuronide

    (R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide. (R)-Carvedilol glucuronide is formed via glucuronidation of (R)-carvedilol by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1 and UGT2B4. (S)-Carvedilol glucuronide is formed via glucuronidation of (S)-carvedilol by UGT2B4 and UGT2B7.

    价 格:¥电议型 号:T35845产 地:中国大陆

  • T35844(R)-Pirtobrutinib;(R)-Pirtobrutinib(R)-Pirtobrutinib

    (R)-Pirtobrutinib ((R)-LOXO-305) is a less active enantiomer of Pirtobrutinib, and Pirtobrutinib is a highly selective and non-covalent next generation BTK inhibitor. Pirtobrutinib (LOXO-305) effectively inhibits diverse BTK C481 substitution mutations[1].

    价 格:¥电议型 号:T35844产 地:中国大陆

  • T358439(R)-HODE cholesteryl ester;9(R)-HODE cholesteryl ester9(R)-HODE cholesteryl ester

    9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 9(R)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.

    价 格:¥电议型 号:T35843产 地:中国大陆

  • T358425-chloro Hydrochlorothiazide;5-chloro Hydrochlorothiazide5-chloro Hydrochlorothiazide

    5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.

    价 格:¥电议型 号:T35842产 地:中国大陆

  • T358415-Benzyloxygramine;5-苄氧基芦竹碱Inhibitor|||5-Benzyloxygramine|||inhibit|||5Benzyloxygramine|||5-Benzylox

    5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.

    价 格:¥电议型 号:T35841产 地:中国大陆

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