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T36058Dibutyl-3-Hydroxybutyl Phosphate；Dibutyl-3-Hydroxybutyl PhosphateDibutyl-3-Hydroxybutyl Phosphate
Dibutyl 3-hydroxybutyl phosphate is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP). Incubation of goldfish liver microsomes in the presence of NADPH has been shown to convert TBP into dibutyl-3-hydroxybutyl phosphate and dibutyl phosphate. Dibutyl-3-hydroxybutyl phosphate has also been produced during radiolysis of TBP.
价 格：￥电议型 号：T36058产 地：中国大陆
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T36057Diallyl Tetrasulfide；Diallyl TetrasulfideICD-1585；ICD-1585
Diallyl tetrasulfide is an organosulfur compound that has been found in A. sativum and has diverse biological activities, including antimicrobial, antioxidant, and anticancer properties.[1],[2],[3],[4] It is active against the bacteria S. aureus and methicillin-resistant S. aureus (MRSA; MICs = 0.5 and 2 mg/L, respectively), as well as the fungi C. albicans, C. krusei, C. glabrata, A. niger, A. flavus, and A. fumigatus (MICs = 0.5, 4, 2, 1, 2, and 4 mg/L, respectively).[1] It reduces cadmium-ind
价 格：￥电议型 号：T36057产 地：中国大陆
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T35899JAK1-IN-8化合物JAK1-IN-8JAK1-IN-8
JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
价 格：￥电议型 号：T35899产 地：中国大陆
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T35898Izencitinib；化合物 IzencitinibTD-1473|||JNJ-8398；TD-1473|||JNJ-8398
Izencitinib (JNJ-8398) is an orally active and gut-selective JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.
价 格：￥电议型 号：T35898产 地：中国大陆
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T35897ASK120067；ASK120067ASK120067
ASK120067 is a potent and orally active inhibitor of EGFRT790M (IC50:0.3 nM) with selectivity over EGFRWT (IC50:6.0 nM). ASK120067 is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC)[1].
价 格：￥电议型 号：T35897产 地：中国大陆
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T35896AZ 12799734；化合物AZ 12799734AZ12799734；AZ12799734
AZ 12799734 is an orally active, selective and potent dual inhibitor of TGFBR1 and ALK5 with inhibitory effects on BMP and TGFβ for the study of tumours.
价 格：￥电议型 号：T35896产 地：中国大陆
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T35894Atiprimod dihydrochloride；Atiprimod dihydrochlorideAtiprimod dihydrochloride
JAK2 inhibitor (IC50 = 397 nM). Also inhibits STAT3 and STAT5 phosphorylation. Inhibits cell growth and induces apoptosis in cells expressing the JAK2V617F mutation.
价 格：￥电议型 号：T35894产 地：中国大陆
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T35893rac-1,2-bis-Palmitoyl-3-chloropropanediol；rac-1,2-bis-Palmitoyl-3-chloropropanediolrac-1,2-bis-Palmi
rac-1,2-bis-Palmitoyl-3-chloropropanediol is a 3-monochloropropane-1,2-diol (3-MCPD) ester.1It has been found as a contaminant in edible olive oils, with the lowest and highest concentrations in extra virgin and olive pomace oils, respectively.rac-1,2-bis-Palmitoyl-3-chloropropanediol has also been found in cottonseed and palm oils, as well as in shortening.2It induces renal tubular necrosis and a decrease in spermatids, but no gross pathological changes, in mice.3
价 格：￥电议型 号：T35893产 地：中国大陆
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T35892Q134RQ134RQ134R
Q134R, a neuroprotective derivative of hydroxyquinoline, effectively inhibits nuclear factor of activated T-cell (NFAT) signaling and possesses the ability to cross the blood-brain barrier. This compound shows promise for research into Alzheimer’s disease (AD) and aging-related disorders[1].
价 格：￥电议型 号：T35892产 地：中国大陆
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T35891pyCTZ TFA；pyCTZ TFApyCTZ TFA
PyCTZ TFA, a pyridyl Coelenterazine (CTZ) analog, is an ATP-independent pyridyl substrate of LumiLuc luciferase. It produces intense blue bioluminescence when luciferases are present, making it suitable for aequorin-based calcium sensing[1].
价 格：￥电议型 号：T35891产 地：中国大陆
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T35890Pentosidine；PentosidinePentosidine
Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditions. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell signaling.[1][2] Pentosidine is a well-characterized natural AGE that is often used as a biomarker for the production of all AGEs. While pentosidine can be measured in urine, the majority of
价 格：￥电议型 号：T35890产 地：中国大陆
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T3589NSC23005 Sodium；化合物NSC23005 SodiumNSC23005 Sodium
NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.
价 格：￥电议型 号：T3589产 地：中国大陆
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T35889PB2；PB2PB2
PB2, a tris(2-carboxyethyl)phosphine (TCEP) analogue, enhances the survival of retinal ganglion cells (RGCs) following axotomy in vitro. Even at nanomolar and picomolar concentrations, PB2 demonstrates pronounced efficacy in promoting RGC survival. Notably, PB2 exhibits superior permeability compared to TCEP. Serving as a potent reducing agent, PB2 provides robust neuroprotection for RGCs[1].
价 格：￥电议型 号：T35889产 地：中国大陆
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T35888PB1；PB1PB1
PB1 is a highly-effective intracellular disulfide reducing agent with notable attributes such as excellent cell permeability, the capacity to generate a substantial intracellular concentration gradient, and remarkable stability. It serves as a borane-protected TCEP (tris(2-carboxyethyl)phosphine) analogue. PB1 demonstrates the potential to enhance the survival of retinal ganglion cells following axotomy in vitro at concentrations in the nanomolar and picomolar range. Consequently, PB1 has proven
价 格：￥电议型 号：T35888产 地：中国大陆
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T35886L-hydroxy Arginine (acetate)；L-hydroxy Arginine (acetate)L-hydroxy Arginine (acetate)
L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. It has been used as a biomarker for reduced nitric oxide formation in patients with cardiovascular disease and metabolic syndrome.
价 格：￥电议型 号：T35886产 地：中国大陆
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T35885KRM-III；化合物KRM-IIIKRM-III
KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell proliferation, with an IC50 of approximately 5 μM.
价 格：￥电议型 号：T35885产 地：中国大陆
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T35884Sialyl-Lewis X；Sialyl-Lewis XSialyl-Lewis X
Sialyl-Lewis X (sLeX), a sialylated fucosylated tetrasaccharide and endogenous antigen, serves as a high-affinity ligand for selectins (E-, P-, and L-selectin)[1]. It interacts with ELAM-1 and CD62, consequently inhibiting CD62-mediated neutrophil recruitment to inflammation sites[2].
价 格：￥电议型 号：T35884产 地：中国大陆
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T35883RNF5 inhibitor inh-02；RNF5 inhibitor inh-02RNF5 inhibitor inh-02；RNF5 inhibitor inh-02
RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation. This compound is valuable for cystic fibrosis research[1].
价 格：￥电议型 号：T35883产 地：中国大陆
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T35882Rizatriptan N-oxide；Rizatriptan N-oxideRizatriptan N-oxide
Rizatriptan N-oxide is a potential impurity found in commercial preparations of rizatriptan.1It is a degradation product formed under oxidative conditions.
价 格：￥电议型 号：T35882产 地：中国大陆
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T35881Resolvin E2；Resolvin E2Resolvin E2
Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA, by 5-lipoxygenase (5-LO) in human polymorphonuclear (PMN) neutrophils.2,3RvE2 (20 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of peritonitis induced by zymosan A .3Hepatic RvE2 levels are increased in m
价 格：￥电议型 号：T35881产 地：中国大陆
