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T73371BAY-3153；化合物 BAY-3153BAY-3153
BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) [1] .
价 格：￥电议型 号：T73371产 地：中国大陆
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T73153EGFR-IN-69；化合物 EGFR-IN-69EGFR-IN-69
EGFR-IN-69 is a potent inhibitor of the EGFR enzyme, demonstrating IC50 values of 4.3 nM for EGFR L858R/T790M/C797S, 6.6 nM for EGFR L858R/T790M, and 25.6 nM for EGFR 19del/T790M/C797S. This compound is utilized in the research of non-small-cell lung cancer (NSCLC).
价 格：￥电议型 号：T73153产 地：中国大陆
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T72743(R)-PF-04991532；化合物 (R)-PF-04991532(R)-PF-04991532
(R)-PF-04991532 is the R-enantiomer of PF-04991532 . PF-04991532 is a potent, hepatoselective glucokinase activator .
价 格：￥电议型 号：T72743产 地：中国大陆
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T72221PF-06815345 hydrochloride；化合物 PF-06815345 hydrochloridePF-06815345 hydrochloride
PF-06815345 hydrochloride, an orally active potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), has an IC50 value of 13.4 μM. It significantly decreases in vivo PCSK9 levels in mice.
价 格：￥电议型 号：T72221产 地：中国大陆
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T72153Topoisomerase IV inhibitor 1；化合物 Topoisomerase IV inhibitor 1Topoisomerase IV inhibitor 1
Topoisomerase IV inhibitor 2 (compound 7d) is a potent inhibitor of DNA topoisomerase IV (TOPO IV), exhibiting IC50 values of 0.23 μM for TOPO IV and 0.43 μM for DNA gyrase. It also demonstrates antibacterial efficacy, with minimum inhibitory concentrations (MICs) of 0.972 μM against Staphylococcus aureus Newman and 0.608 μM against Escherichia coli ATCC8739 [1].
价 格：￥电议型 号：T72153产 地：中国大陆
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T71539AFN-1252 tosylate hydrate；化合物 AFN-1252 tosylate hydrateAFN-1252 tosylate hydrate
AFN-1252, also known as AFN-12520000; API-1252; Debio-1452, is FASII Inhibitor which is potentially for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long elimination half-live and efficacy in animal models. AFN-1252 efficiently blocked daptomycin-induced phospholipid decoy production, even in the case of isolates resistant to AFN-1252, which prevented the inactivation of daptomyci
价 格：￥电议型 号：T71539产 地：中国大陆
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T71538AMPCP；化合物 AMPCPAMPCP
AMPCP is an Ecto-5´-nucleotidase (CD73) inhibitor.
价 格：￥电议型 号：T71538产 地：中国大陆
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T71537Tofenacin hydrochloride；化合物 Tofenacin hydrochlorideTofenacin hydrochloride
Tofenacin hydrochloride is an antidepressant drug with a tricyclic-like structure. It acts as a serotonin-norepinephrine reuptake inhibitor, and based on its close relation to orphenadrine, may also possess anticholinergic and antihistamine properties. Tofenacin is also the major active metabolite of orphenadrine and likely plays a role in its beneficial effects against depressive symptoms seen in Parkinson´s disease patients.
价 格：￥电议型 号：T71537产 地：中国大陆
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T71536Mdl 28815；化合物 Mdl 28815Mdl 28815
Mdl 28815 is a potent inhibitor of 2,3-oxidosqualene cycloartenol & lanosterol cyclases.
价 格：￥电议型 号：T71536产 地：中国大陆
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T71535GlmU-IN-5175178；化合物 GlmU-IN-5175178GlmU-IN-5175178
GlmU-IN-5175178 is an inhibitor of the acetyltransferase activity of Escherichia coli N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU).
价 格：￥电议型 号：T71535产 地：中国大陆
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T71534LCIA-1 (Free base)；化合物CIA-1CIA-1(Free base）；CIA-1(Free base）
CIA-1 (Free base) is a nuclear receptor COUP-TFII inhibitor with IC50 values ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines. CIA-1 (Free base) inhibits tumor growth in a mouse model of prostate cancer xenografts.
价 格：￥电议型 号：T71534L产 地：中国大陆
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T71534CIA-1 hcl(452087-38-6 Free base)；化合物CIA-1 hcl(452087-38-6 Free base)CIA-1 hcl(452087-38-6 Free base)
CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.
价 格：￥电议型 号：T71534产 地：中国大陆
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T71533NCS-356 sodium monohydrate；化合物 NCS-356 sodium monohydrateNCS-356 sodium monohydrate
NCS-356 sodium monohydrate is a GHB receptor agonist.
价 格：￥电议型 号：T71533产 地：中国大陆
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T71532Fondaparinux free base；化合物 Fondaparinux free baseFondaparinux free base
Fondaparinux Free Base is a synthetic pentasaccharide that mediates the interaction of HEPARIN with ANTITHROMBINS and inhibits FACTOR Xa; it is used for prevention of VENOUS THROMBOEMBOLISM after surgery. Fondaparinux is a clinically approved anticoagulant pentasaccharide for the treatment of thrombotic diseases, displays better efficacy and biosafety than other heparin-based anticoagulant drugs.
价 格：￥电议型 号：T71532产 地：中国大陆
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T71531Metamizil hydrochloride；化合物 Metamizil hydrochlorideMetamizil hydrochloride
Metamizil hydrochloride is a cholinolytic agent -- an agent that blocks the transmission of excitation from cholinergic nerve fibers -- and an antagonist of the mediator acetylcholine.
价 格：￥电议型 号：T71531产 地：中国大陆
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T71530K252d；化合物 K252dK252d
K252d is an indolocarbazole alkaloid found in Nocardiopsis. It is a PKC inhibitor that inhibits PKC isolated from rat brain, as well as, calcium- and calmodulin-dependent phosphodiesterase isolated from bovine heart.
价 格：￥电议型 号：T71530产 地：中国大陆
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T7153Vanoxerine dihydrochloride；伐诺司林二盐酸盐GBR-12909 dihydrochloride|||I893 dihydrochloride；GBR-12909 dihydr
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)
价 格：￥电议型 号：T7153产 地：中国大陆
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T71153FN-439；化合物 FN-439FN-439
FN-439 is a selective inhibitor of collagenase-1, characterized by an IC50 value of 1 μM, indicating its effectiveness in inhibiting this enzyme. Due to its specificity and activity, FN-439 serves as a valuable tool for cancer and inflammation research.
价 格：￥电议型 号：T71153产 地：中国大陆
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T71020PF-04671536；化合物 PF-04671536PF-04671536
PF-04671536 is a highly potent and selective inhibitor of phosphodiesterase 8B (PDE8B) phosphodiesterase 8A (PDE8A). In primary human pancreatic islets, PF-04671536 increases insulin secretion in a glucose-dependent manner.
价 格：￥电议型 号：T71020产 地：中国大陆
