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T81533PDE5-IN-11;化合物 PDE5-IN-11PDE5-IN-11
PDE5-IN-11 is a potent PDE5 inhibitor, exhibiting an IC50 of 40 nM, and also displays inhibitory activity against PDE4 and PDE6 with IC50 values of 1.78 μM and 0.09 μM, respectively [1].
价 格:¥电议型 号:T81533产 地:中国大陆
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T81532Pedaliin 6’’-acetate;化合物 Pedaliin 6’’-acetatePedaliin 6''-acetate
Pedaliin 6´´-acetate (compound 10), a natural product extracted from Dracocephalum tanguticum, exhibits antioxidative properties and a cytoprotective effect against doxorubicin (DOX)-induced toxicity in H9c2 cardiomyocytes, with an effective concentration (EC50) of 19.1 μM [1].
价 格:¥电议型 号:T81532产 地:中国大陆
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T81531Pedunculosumoside F;化合物 Pedunculosumoside FPedunculosumoside F
Pedunculosumoside F, a homoflavonoid glucoside extracted from Ophioglossum pedunculosum, exhibits cytotoxicity against HepG2 22.15 cells, presenting a CC50 value of 56.7 μM, yet lacks anti-HBV activity. Conversely, its analogs inhibit HBsAg secretion in HBV-infected HepG2 2.2.15 cells [1].
价 格:¥电议型 号:T81531产 地:中国大陆
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T81530Pegacaristim;化合物 PegacaristimPegacaristim
Pegacaristim, a monoclonal antibody, exhibits thrombopoietic activity by promoting the generation of platelets [1] [2].
价 格:¥电议型 号:T81530产 地:中国大陆
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T8153glycohyodeoxycholic acid;甘氨猪去氧胆酸glycohyodeoxycholic acid
glycohyodeoxycholic acid is a major metabolite of the secondary bile acid hyodeoxycholic acid in humans.
价 格:¥电议型 号:T8153产 地:中国大陆
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T81153Sitakisogenin;化合物 SitakisogeninSitakisogenin
Sure, please provide the description of the chemical compound you´d like to be rewritten.
价 格:¥电议型 号:T81153产 地:中国大陆
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T80974TMX-4153;化合物 TMX-4153TMX-4153
TMX-4153 is a bivalent degrader that selectively targets and rapidly degrades endogenous PIP4K2C through recruitment of the von Hippel-Lindau (VHL) E3 ligase complex, demonstrating a K D of 42 nM. It is applicable in the synthesis of PROTAC [1].
价 格:¥电议型 号:T80974产 地:中国大陆
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T80153Maurocalcine;化合物 MaurocalcineMaurocalcine
Maurocalcine is a cell-permeable agonist for ryanodine receptor (RyR) subtypes 1, 2, and 3. It enhances [3 H]ryanodine binding to RyR1 with an EC50 of 2558 nM and demonstrates an apparent affinity for RyR2 at 14 nM. This compound is suitable for in vivo cell tracking and other cellular imaging applications [1] [2] [3].
价 格:¥电议型 号:T80153产 地:中国大陆
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T79675Antibacterial agent 153;化合物 Antibacterial agent 153Antibacterial agent 153
Antibacterial agent 153 is a broad-spectrum agent that eradicates bacteria by targeting their cell membranes and is employed in research on bacterial infections [1].
价 格:¥电议型 号:T79675产 地:中国大陆
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T79646Anticancer agent 153;化合物 Anticancer agent 153Anticancer agent 153
Anticancer Agent 153 (Compound 3) promotes apoptosis through the generation of Reactive Oxygen Species (ROS) and elevates the loss of Mitochondrial Membrane Potential (MMP), effectively inhibiting cancer cell proliferation [1].
价 格:¥电议型 号:T79646产 地:中国大陆
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T79153DG-8;化合物 DG-8DG-8
DG-8 serves as a potent inhibitor of STAT3-dependent transcription, exhibiting an IC50 of 0.98 μM, and also functions as a fluorescent probe endowed with a dansyl moiety [1].
价 格:¥电议型 号:T79153产 地:中国大陆
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T78153PSMA I&T;化合物 PSMA I&TPSMA I&T
PSMA I&T, a potent inhibitor of prostate-specific membrane antigen (PSMA), facilitates SPECT/CT imaging and radionuclide research in prostate cancer (PCa) [1].
价 格:¥电议型 号:T78153产 地:中国大陆
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T77781Lotiglipron;化合物 LotiglipronPF-07081532;PF-07081532
Lotiglipron (PF-07081532) is an orally active and potent GLP-1R agonist that reduces blood glucose and body weight and may be useful in the study of type 2 diabetes mellitus (T2DM) and obesity.
价 格:¥电议型 号:T77781产 地:中国大陆
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T77153Cudarolimab;化合物 CudarolimabCudarolimab
Cudarolimab (IBI101) is a fully human monoclonal antibody targeting OX40 (CD134), a costimulatory molecule expressed by activated immune cells. By inhibiting the interaction between OX40 and its ligand OX40L, Cudarolimab demonstrates antitumor activity, making it relevant for cancer research [1].
价 格:¥电议型 号:T77153产 地:中国大陆
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T76722Sarilumab;萨瑞鲁单抗REGN-88|||SAR-153191;REGN-88|||SAR-153191
Sarilumab (SAR-153191)is a potent interleukin-6 IL-6 receptor antagonist and a human immunoglobulin G1 monoclonal antibody. Sarilumab inhibits IL-6-mediated signaling and reduces inflammation.Sarilumab is used for the prevention and treatment of rheumatoid arthritis.
价 格:¥电议型 号:T76722产 地:中国大陆
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T76153PNGase F;化合物 PNGase FPNGase F
PNGase F, a glycosidase, catalyzes the cleavage of an internal glycoside bond in an oligosaccharide. PNGase F removes nearly all N-linked oligosaccharides from glycoproteins [1] [2] .
价 格:¥电议型 号:T76153产 地:中国大陆
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T75836JIP-1(153-163) TFA;化合物 JIP-1(153-163) TFAJIP-1(153-163) TFA
JIP-1(153-163) TFA (TI-JIP TFA), a c-JNK peptide inhibitor derived from residues 153-163 of the JNK-interacting protein-1 (JIP-1), exhibits modifications at Phe-11 with a C-terminal amide [1].
价 格:¥电议型 号:T75836产 地:中国大陆
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T75153ATL 1102;化合物 ATL 1102ATL 1102
ATL 1102 is a novel second-generation antisense oligonucleotide to CD49d mRNA
价 格:¥电议型 号:T75153产 地:中国大陆
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T75118AN15368;化合物 AN15368AN15368
AN15368, an orally administered small-molecule precursor, undergoes activation by parasite carboxypeptidase, yielding a product that interferes with the messenger RNA processing pathway in T. cruzi. This compound shows promise for both preventing and investigating potential treatments for Chagas disease [1].
价 格:¥电议型 号:T75118产 地:中国大陆
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T74276LEB-03-153;化合物 LEB-03-153LEB-03-153
LEB-03-153 is a WEE1 DUBTAC (deubiquitinase-targeting chimera) linking AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 through no linker [1] .
价 格:¥电议型 号:T74276产 地:中国大陆