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T60144TDI-011536;化合物TDI-011536TDI-011536
TDI-011536, a potent Lats kinase inhibitor, disrupts Hippo-Yap signaling and promotes the proliferation of lesioned heart muscle cells. This compound is valuable for research in organ conservation and regeneration.
价 格:¥电议型 号:T60144产 地:中国大陆
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T60085MM3122;化合物MM3122GTPL11533|||MM-3122|||Ac-GQFR-kbt;GTPL11533|||MM-3122|||Ac-GQFR-kbt
MM3122 (MM-3122) is a selective type II transmembrane serine protease (TMPRSS2) inhibitor, IC50 = 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells.
价 格:¥电议型 号:T60085产 地:中国大陆
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T5S1530Isochlorogenic acid C异绿原酸C金银花|||异绿原酸C
1. Isochlorogenic acid C has antioxidant activity.
价 格:¥电议型 号:T5S1530产 地:中国大陆
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T5348SNG-1153;化合物SNG-1153SNG-1153
SNG-1153 is a estrogen receptor ER-alpha36 modulator.
价 格:¥电议型 号:T5348产 地:中国大陆
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T41153BOP-JF646;BOP-JF646BOP-JF646;BOP-JF646
BOP-JF646 is a fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP conjugated to Janelia Fluor?646. Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over long time-course experiments. Excitation maximum = 655 nm; emission maximum = 672 nm.
价 格:¥电议型 号:T41153产 地:中国大陆
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T40345AV-153;AV-153AV-153
AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand breaks, resulting in reduced DNA damage and stimulation of DNA repair in human cells in vitro. AV-153 also interacts with thymine and cytosine and influences poly(ADP)ribosylation. Moreover, AV-153 exhibits anti-cancer activity.
价 格:¥电议型 号:T40345产 地:中国大陆
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T40153BAMEA-O16B;BAMEA-O16BBAMEA-O16B;BAMEA-O16B
BAMEAO16B is a lipid nanoparticle that incorporates disulfide bonds for efficient delivery of Cas9 mRNA and sgRNA into cells. In the intracellular environment, BAMEAO16B responds to reduction by releasing RNA, facilitating genome editing. This compound is valuable for gene editing research purposes.
价 格:¥电议型 号:T40153产 地:中国大陆
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T3S1534Secoxyloganin断氧化马钱苷断氧化马钱苷|||幼枝含断氧化马钱子甙|||金银花
Secoxyloganin possesses a hepato-protective effect. Secoxyloganin possesses antibacterial activity. Secoxyloganin has cytotoxic activity against UACC-62 cell line.Secoxyloganin possesses the perfect protective effect on PRRSV infected cell and with the minimum protection concentration of 6. 25 μg/mL.
价 格:¥电议型 号:T3S1534产 地:中国大陆
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T3S0153Xanthatin苍耳亭苍耳亭|||叶黄制菌素
1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell proliferation possibly associated with activation of Wnt/β-catenin pathway and its activity against melanoma tumor might also be relevant to inhibition of angiogenesis.
价 格:¥电议型 号:T3S0153产 地:中国大陆
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T39954AU-15330;化合物AU-15330AU-15330
AU-15330 is a protein hydrolysis-targeted chimeric (PROTAC) degrader of the SWI/SNF ATPase subunits SMARCA2 and SMARCA4.AU-15330 potently inhibits tumor growth in a prostate cancer xenograft model and acts synergistically with the AR antagonist enzalutamide.AU-15330 shows partial therapeutic efficacy and non-toxicity with the AR antagonist enzalutamide in a desmoplasia-resistant prostate cancer (CRPC) model. AU-15330 showed partial therapeutic efficacy in a denervation-resistant prostate cancer
价 格:¥电议型 号:T39954产 地:中国大陆
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T39153ICG-amine;ICG-amineICG-amine
ICG amine, a tricarbocyanine dye, is a near-infrared fluorescent probe that efficiently binds to amino acid residues without the requirement of condensing agents.
价 格:¥电议型 号:T39153产 地:中国大陆
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T38153NF-κB Inhibitor (trifluoroacetate salt);NF-κB Inhibitor (trifluoroacetate salt)NF-κB Inhibitor (trif
NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.1It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.1In this way, NF-κB inhibitor blocks gene expression that is regulated by NF-κB.2,3This peptide is commonly used to evaluate the role of NF-κB signaling in cellular responses.4,5
价 格:¥电议型 号:T38153产 地:中国大陆
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T37799PF 04671536 hydrochloridePF 04671536 hydrochloridePF 04671536 hydrochloride
Potent and selective PDE8B/8A inhibitor ( IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.
价 格:¥电议型 号:T37799产 地:中国大陆
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T37153Sodium 3-methyl-2-oxobutanoate;3-methyl-2-oxobutyrateSodium 3-methyl-2-oxobutanoate
Sodium 3-methyl-2-oxobutanoate is the precursor of pantothenic acid in Escherichia coli. Sodium 3-methyl-2-oxobutanoate and alpha-ketoisocaproic ac can be enhanced in vitro experiments.
价 格:¥电议型 号:T37153产 地:中国大陆
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T36704CCT241533 dihydrochloride;CCT 241533 dihydrochlorideCCT 241533 dihydrochloride;CCT 241533 dihydrochl
Potent Chk2 inhibitor (IC50 = 3 nM). Shows >63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. Inhibits Chk2 activation in response to etoposide-induced DNA damage in HT29 cells. Blocks ionizing radiation-induced apoptosis of mouse thymocytes.
价 格:¥电议型 号:T36704产 地:中国大陆
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T36405Pro-Adrenomedullin (153-185), human;Pro-Adrenomedullin (153-185), humanPro-Adrenomedullin (153-185),
Pro-Adrenomedullin(153-185),human, (C143H224N42O43), a peptide with the sequence H2N-SLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL-OH, MW= 3219.6. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaechromyctoma in 19931. AM was initially identified as a vasodilator, some have cited this as the most potent endogenous vasodilatory peptide found in the body2. Differences in opinion regarding the ability of AM to relax vascular tone arises from the differences in the model system
价 格:¥电议型 号:T36405产 地:中国大陆
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T3615315(S)-15-methyl Prostaglandin D2;15(S)-15-methyl Prostaglandin D215(S)-15-methyl Prostaglandin D2;15
15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2 . In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet aggregation. It also exhibits strong antifertility activity in hamsters (200-fold more potent than PGD2).
价 格:¥电议型 号:T36153产 地:中国大陆
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T36126TMP-153;化合物 TMP-153TMP-153
TMP-153 is a novel and potent ACAT inhibitor with an IC50 value of 5-10 nM for intestinal and hepatic ACAT in animals.TMP-153 has a hypocholesterolemic effect, inhibiting cholesterol uptake and lowering plasma cholesterol in rats and hamsters.
价 格:¥电议型 号:T36126产 地:中国大陆
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T3572NSC 15364;化合物1,3-Bis(4-aminophenyl)urea1,3-Bis(4-aminophenyl)urea|||NSC15364;1,3-Bis(4-aminophenyl)u
NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.
价 格:¥电议型 号:T3572产 地:中国大陆
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T3558EBE-A22;化合物EBE-A22PD153035 Analog 63;PD153035 Analog 63
EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.
价 格:¥电议型 号:T3558产 地:中国大陆