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  • T63924XY153；化合物 XY153XY153

    XY153 (compound 8l) is a BD2 selective BET inhibitor that selectively binds BRD4 BD2. XY153 binds BRD4 BD2 (IC50: 0.79 nM), BRD3 BD2 (IC50: 5.31 nM) and BRD2 BD2 (IC50: 5.09 nM). XY153 can be used to study acute myeloid leukaemia and cancer.

    价 格：￥电议型 号：T63924产 地：中国大陆

  • T63508OM-153；化合物 OM-153OM-153

    OM-153 is a potent inhibitor of tankyrase, acting on tankyrase 1 (IC50: 13 nM) and tankyrase 2 (IC50: 2 nM), and inhibiting WNT/β-linked protein signaling and proliferation in COLO 320DM.

    价 格：￥电议型 号：T63508产 地：中国大陆

  • T63316BGC-20-1531 free base；化合物 BGC-20-1531 free baseBGC-20-1531 free base

    BGC-20-1531 (PGN 1531) free base is a selective and potent prostaglandin EP4 receptor antagonist (pKB: 7.6) that exhibits potential for migraine research.

    价 格：￥电议型 号：T63316产 地：中国大陆

  • T63153APJ receptor agonist 5；化合物 APJ receptor agonist 5APJ receptor agonist 5

    APJ receptor agonist 5 (compound 3) is a potent and orally active apelin receptor (APJ) agonist (EC 50:0.4 nM). APJ receptor agonist 5 has excellent pharmacokinetic profiles in rodent models of heart failure (HF) and an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 can improve cardiac function and can be used in the study of HF disease.

    价 格：￥电议型 号：T63153产 地：中国大陆

  • T62544MK-8153；化合物 MK-8153MK-8153

    MK-8153 is a selective, potent, orally active inhibitor of extrarenal medullary potassium channels (ROMK), acting on ROMK EP (IC50: 5 μM) and hERG EP (IC50: 34 μM).MK-8153 can be used as a diuretic.

    价 格：￥电议型 号：T62544产 地：中国大陆

  • T62153JAK3/BTK-IN-5；化合物 JAK3/BTK-IN-5JAK3/BTK-IN-5

    JAK3/BTK-IN-5 is a potent inhibitor of JAK3/BTK. where BTK and JAK3 are two key targets in autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway has a synergistic effect and JAK3/BTK-IN-5 has potential research value for JAK3 kinase and/or BTK-related diseases.

    价 格：￥电议型 号：T62153产 地：中国大陆

  • T61539AXKO-0046；化合物 AXKO-0046AXKO-0046

    AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.

    价 格：￥电议型 号：T61539产 地：中国大陆

  • T61538Antiparasitic agent-10；化合物 Antiparasitic agent-10Antiparasitic agent-10

    Antiparasitic agent-10 (Compound 94) is a potent anti-parasitic agent specifically designed to target and combat parasitic infections. It demonstrates notable anti-schistosomal activity, particularly against adults of Schistosoma mansoni. As a result, this compound holds significant potential for utilization in Schistosomiasis research as a viable treatment option [1].

    价 格：￥电议型 号：T61538产 地：中国大陆

  • T61537ASIC-IN-1；化合物 ASIC-IN-1ASIC-IN-1

    ASIC-IN-1 is a potent inhibitor of acid-sensing ion channels, demonstrating an IC 50 value of less than 10 μM. It effectively reduces pain intensity in a dose-dependent manner [1].

    价 格：￥电议型 号：T61537产 地：中国大陆

  • T61536A1AR antagonist 4；化合物 A1AR antagonist 4A1AR antagonist 4

    A1AR antagonist 4 (compound 22) is a highly developed chemical compound that acts as a potent and selective antagonist of the A1 adenosine receptor (A1AR). It possesses a pIC50 value of 5.51 and a pKi value of 6.29 [1].

    价 格：￥电议型 号：T61536产 地：中国大陆

  • T61535Neldazosin；奈达唑嗪Neldazosin

    Neldazosin is used as a potent α1-adrenoceptor antagonist.

    价 格：￥电议型 号：T61535产 地：中国大陆

  • T61534Glyoxalase I inhibitor 3；化合物 Glyoxalase I inhibitor 3Glyoxalase I inhibitor 3

    Glyoxalase I Inhibitor 3 (compound 22g), a potent inhibitor of glyoxalase I (GLO1), demonstrates an IC50 of 0.011 μM, indicating significant efficacy. This compound shows promise for research into depression and anxiety [1].

    价 格：￥电议型 号：T61534产 地：中国大陆

  • T61533DNA-PK-IN-9；化合物 DNA-PK-IN-9DNA-PK-IN-9

    DNA-PK-IN-9 (also known as compound YK6) is a highly potent inhibitor of DNA-dependent protein kinase (DNA-PK), displaying an IC50 value of 10.47 nM. DNA-PK-IN-9 holds significant potential in anticancer research [1].

    价 格：￥电议型 号：T61533产 地：中国大陆

  • T61532Tubulin polymerization-IN-6；化合物 Tubulin polymerization-IN-6Tubulin polymerization-IN-6

    Tubulin polymerization-IN-6 (compound 5f) is a potent inhibitor of tubulin polymerization, with an IC50 of 1.09 μM. It not only inhibits cell migration and tube formation but also has anti-angiogenic properties. Additionally, Tubulin polymerization-IN-6 has been found to effectively hinder tumor growth in HT29 xenograft Balb/c nude mice [1].

    价 格：￥电议型 号：T61532产 地：中国大陆

  • T61531NFATc1-IN-1；化合物NFATc1-IN-1NFATc1-IN-1

    NFATc1-IN-1 (also known as compound A04) is a highly effective inhibitor of osteoclast formation induced by RANKL, with an IC50 of 1.57 μM. It exerts its anti-osteoclastogenic effects by attenuating the RANKL-induced nuclear translocation of NFATc1. Due to its remarkable properties, NFATc1-IN-1 holds significant potential for advancing research related to osteoclastic diseases [1].

    价 格：￥电议型 号：T61531产 地：中国大陆

  • T61530PBENZ-DBRMD；化合物 PBENZ-DBRMDPBENZ-DBRMD

    PBENZ-DBRMD, a powerful iodothyronine deiodinase type 3 (DIO3) inhibitor, exhibits anti-proliferative activity and promotes apoptosis. This compound holds potential for utilization in cancer research [1].

    价 格：￥电议型 号：T61530产 地：中国大陆

  • T6153Icotinib；埃克替尼BPI-2009|||BPI-2009H|||Conmana；BPI-2009|||埃克替尼|||BPI-2009H|||Conmana

    Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.

    价 格：￥电议型 号：T6153产 地：中国大陆

  • T61172NRX-1532；化合物NRX-1532NRX1532|||NRX 1532；NRX1532|||NRX 1532

    NRX-1532 is a small molecule β-catenin:β-TrCP interaction enhancer.

    价 格：￥电议型 号：T61172产 地：中国大陆

  • T61153Mepazine hydrochloride；化合物 Mepazine hydrochlorideMepazine hydrochloride

    Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective inhibitor of the MALT1 protease, with IC50 values of 0.83 μM for GSTMALT1 full length and 0.42 μM for GSTMALT1 325-760. It enhances apoptosis and influences the viability of ABC-DLBCL cells [1].

    价 格：￥电议型 号：T61153产 地：中国大陆

  • T60649AV-153 free base；化合物 AV-153 free baseAV-153 free base

    AV-153 free base is a 1,4-dihydropyridine (1,4-DHP) derivative. AV-153 free base is an antimutagenic with anti-cancer activity. AV-153 free base interacts with cytosine and thymine and has an influence on poly(ADP)ribosylation. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro [1] [2] [3].

    价 格：￥电议型 号：T60649产 地：中国大陆

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