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T61902Anticancer agent 69;化合物 Anticancer agent 69Anticancer agent 69
Anticancer agent 69 (Compound 34) is an effective selective anticancer agent with selective inhibition on human prostate cancer cell line PC3 (IC50=26 nM). Anticancer agent 69 can increase ROS level and down-regulate EGFR, thus inducing apoptosis.
价 格:¥电议型 号:T61902产 地:中国大陆
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T61683Antiparasitic agent-9;化合物 Antiparasitic agent-9Antiparasitic agent-9
Antiparasitic agent-9 (compound 47) is a highly active and orally administered antiparasitic agent, exhibiting potent antiparasitic efficacy against the human parasite [1].
价 格:¥电议型 号:T61683产 地:中国大陆
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T61636ATR-IN-19;化合物 ATR-IN-19ATR-IN-19
ATR-IN-19 (Compound 15 R-configure) is an ATR inhibitor [1].
价 格:¥电议型 号:T61636产 地:中国大陆
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T61416Antileishmanial agent-9;化合物 Antileishmanial agent-9Antileishmanial agent-9
Antileishmanial agent-9 (compound 16c) exhibits potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 4.01 μM. In addition, this compound demonstrates relatively low cytotoxicity in L-6 cells, with an IC50 value of 40.1 μM [1].
价 格:¥电议型 号:T61416产 地:中国大陆
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T61400Anti-inflammatory agent 9;化合物 Anti-inflammatory agent 9Anti-inflammatory agent 9
Anti-inflammatory agent 9 (compound 28)Anti-inflammatory agent 9 (compound 28) is a benzimidazothiazole derivative derived from tilomisole. It exhibits a higher affinity for the COX-2 enzyme compared to COX-1, thereby demonstrating promising anti-inflammatory properties. Furthermore, it demonstrates oral bioavailability [1].
价 格:¥电议型 号:T61400产 地:中国大陆
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T61397AChE/BChE-IN-9;化合物 AChE/BChE-IN-9AChE/BChE-IN-9
AChE/BChE-IN-9 (Compound 7a) is a potent orally active inhibitor of AChE and BChE, with IC50 values of 5.74 μM and 14.05 μM against hAChE and eqBChE, respectively. It also demonstrates effective antioxidant activity, with an IC50 value of 57.35 μM. Additionally, AChE/BChE-IN-9 exhibits the ability to chelate iron and modulate the aggregation of amyloid β 1-42. Notably, AChE-IN-16 has the ability to cross the blood-brain barrier [1].
价 格:¥电议型 号:T61397产 地:中国大陆
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T61378Anticancer agent 29;化合物 Anticancer agent 29Anticancer agent 29
Anticancer agent 29 (Compd E/Z-6f) exhibits potent anticancer activity, as indicated by IC50 values of 0.054 μM, 0.127 μM, 0.129 μM, and 0.396 μM for CDK2, CDK1, CDK4, and CDK6, respectively [1].
价 格:¥电议型 号:T61378产 地:中国大陆
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T61355APX2039;化合物APX2039APX-2039|||APX 2039;APX-2039|||APX 2039
APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.APX2039 exhibits potent antifungal activity and blocks the localization of GPI (glycosylphosphatidylinositol) anchored cell wall mannoproteins. APX2039 has potent antifungal activity and blocks the localization of GPI (glycosylphosphatidylinositol)-anchored cell wall mannoproteins.APX2039 can be used to s
价 格:¥电议型 号:T61355产 地:中国大陆
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T61257Antifungal agent 19;化合物 Antifungal agent 19Antifungal agent 19
Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).
价 格:¥电议型 号:T61257产 地:中国大陆
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T60129MT189;化合物MT189Antiproliferative agent-14;Antiproliferative agent-14
MT189 (Antiproliferative agent-14) is a potent tubulin polymerization inhibitor, with an IC50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the ability to arrest cells at G2/M phases of the cell cycle.
价 格:¥电议型 号:T60129产 地:中国大陆
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T6003GSK1904529A;化合物GSK1904529AGSK 4529;GSK 4529
GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
价 格:¥电议型 号:T6003产 地:中国大陆
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T5409AZD3229;化合物AZD3229AZD3229
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It demonstrates potent single-digit nM growth inhibition across a broad cell panel.
价 格:¥电议型 号:T5409产 地:中国大陆
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T4997Umeclidinium bromide;芜地溴铵GSK573719A;芜地溴铵|||GSK573719A
Umeclidinium bromide (GSK573719A) is a novel mAChR antagonist.
价 格:¥电议型 号:T4997产 地:中国大陆
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T4476AS1517499;化合物AS1517499AS1517499
AS1517499 is a potent STAT6 inhibitor with IC50 of 21 nM
价 格:¥电议型 号:T4476产 地:中国大陆
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T40339Antitubercular agent-9;Antitubercular agent-9Antitubercular agent-9
Antitubercular agent-9 exhibits potent activity against tuberculosis, demonstrating a minimum inhibitory concentration (MIC) range of 1.03-2.32 μM.
价 格:¥电议型 号:T40339产 地:中国大陆
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T40259AB-729;AB-729AB-729
AB-729, a nucleoside analogue functioning as an RNA interference (RNAi), links to a GalNAc (N-acetylgalactosamine) trimer ligand facilitating hepatocyte uptake through the asialoglycoprotein receptor (ASGR). This compound effectively impedes viral replication and diminishes HBV antigens.
价 格:¥电议型 号:T40259产 地:中国大陆
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T40077ATR-IN-9;ATR-IN-9ATR-IN-9
ATR-IN-9 is a highly effective inhibitor of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). With an IC50 value as low as 10 nM, ATR-IN-9 demonstrates exceptional potency.
价 格:¥电议型 号:T40077产 地:中国大陆
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T3S0289Araloside X;化合物 T3S0289Araloside X
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane peroxidation induced by oxygen free radicals. Aralosides have anti-inflammatory effect, they also can effectively prevent acute alcoholic liver injury.
价 格:¥电议型 号:T3S0289产 地:中国大陆
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T3990AA26-9;化合物AA26-9AA26-9
AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.
价 格:¥电议型 号:T3990产 地:中国大陆
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T39896ALK-IN-9;ALK-IN-9ALK-IN-9
ALK-IN-9 (compound 40) is a highly effective ALK inhibitor. It demonstrates remarkable inhibitory activity against cell proliferation, with IC50 values of <0.2 nM for Ba/F3-EML4-ALK, KM 12 (TPM3-TRKA), and KG-l cell (OP2-FGFR1).
价 格:¥电议型 号:T39896产 地:中国大陆