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T68356AM-3189；化合物 AM-3189AM-3189
AM-3189 is a potent and selective GPR40 Agonist with minimal CNS penetration, superior pharmacokinetic properties and in vivo efficacy comparable to AMG 837. AM-3189 maintains the in vivo efficacy of AMG 837 while displaying a superior pharmacokinetic profile and minimal CNS exposure. Similar to AMG 837, while highly potent on GPR40, AM-3189 was highly selective over the closely related GPCRs, GPR41 and GPR43. 13kdemonstrated low clearance, moderate volume of distribution, and good oral bioavai
价 格：￥电议型 号：T68356产 地：中国大陆
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T68240AZD-9819；化合物 AZD-9819AZD-9819
AZD-9819 is an inhibitor of human neutrophil elastase for potential treatment of chronic obstructive pulmonary disease (COPD).
价 格：￥电议型 号：T68240产 地：中国大陆
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T67846AKR1C3-IN-9；化合物AKR1C3-IN-9AKR1C3-IN-9
AKR1C3-IN-9 is a selective Aldo-keto Reductase 1C3 (AKR1C3) inhibitor (IC50= 8.92 nM). AKR1C3-IN-9 can significantly reverse the Doxorubicin (DOX) resistance in a resistant breast cancer cell line.
价 格：￥电议型 号：T67846产 地：中国大陆
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T6772AZD3839 free base；化合物AZD3839AZD3839；AZD3839
AZD3839 free base is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.
价 格：￥电议型 号：T6772产 地：中国大陆
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T67705mTOR inhibitor 9a；化合物 mTOR inhibitor 9amTOR inhibitor 9a
mTOR inhibitor 9a inhibited the growth of human LNCap cells with an ic50 of 80 nm. 1-methyl-3 -{4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl}urea may have antitumor activity.
价 格：￥电议型 号：T67705产 地：中国大陆
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T67601(4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxyl
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67601 and the CAS number is 103335-55-3.
价 格：￥电议型 号：T67601产 地：中国大陆
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T6760APS-2-79 hydrochloride；化合物APS-2-79APS-2-79 HCl|||APS-2-79；APS-2-79 HCl|||APS-2-79
APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK.
价 格：￥电议型 号：T6760产 地：中国大陆
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T6757AMG319；化合物AMG319AMG319
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.
价 格：￥电议型 号：T6757产 地：中国大陆
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T6753AI-10-49；化合物AI-10-49AI-10-49
AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.
价 格：￥电议型 号：T6753产 地：中国大陆
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T67508(2S,4aR,4bS,6aS,7aS,8aS,8bS,8cR,8dR,9aR,9bR)-2,9b-Dihydroxy-4a,6a-dimethylhexadecahydro-1H-cycloprop
(2S,4aR,4bS,6aS,7aS,8aS,8bS,8cR,8dR,9aR,9bR)-2,9b-Dihydroxy-4a,6a-dimethylhexadecahydro-1H-cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthren-7(7aH)-one is a useful organic compound for research related to life sciences. The catalog number is T67508 and the CAS number is 82543-16-6.
价 格：￥电议型 号：T67508产 地：中国大陆
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T67388N-(1-((6aR,8R,9aR)-9-Cyano-9-hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]triox
N-(1-((6aR,8R,9aR)-9-Cyano-9-hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide is a useful organic compound for research related to life sciences and the catalog number is T67388.
价 格：￥电议型 号：T67388产 地：中国大陆
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T6712Tyrphostin AG 879；化合物Tyrphostin AG 879AG 879；AG 879
Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.
价 格：￥电议型 号：T6712产 地：中国大陆
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T66996(4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahyd
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66996 and the CAS number is 104239-97-6.
价 格：￥电议型 号：T66996产 地：中国大陆
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T65298(4aR,4bS,6aS,7S,9aS,9bS,11aR)-Methyl 4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetra
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-Methyl 4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate is a useful organic compound for research related to life sciences and the catalog number is T65298.
价 格：￥电议型 号：T65298产 地：中国大陆
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T64681(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclo
(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(tosyloxy)acetate is a useful organic compound for research related to life sciences and the catalog number is T64681.
价 格：￥电议型 号：T64681产 地：中国大陆
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T64198A3N19；化合物 A3N19A3N19
A3N19 is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase and is able to act on HIV-1 IIIB (EC50: 3.28 nM).
价 格：￥电议型 号：T64198产 地：中国大陆
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T64051ALK5-IN-9；化合物 ALK5-IN-9ALK5-IN-9
ALK5-IN-9 is a potent, orally active inhibitor of TGFβRI (ALK5). ALK5-IN-9 inhibits ALK5 autophosphorylation (IC50: 25 nM) and inhibits NIH3T3 cell activity (IC50: 74.6 nM). ALK5-IN-9 has shown research potential in cancer diseases.
价 格：￥电议型 号：T64051产 地：中国大陆
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T63945Antitubercular agent-19；化合物 Antitubercular agent-19Antitubercular agent-19
Antitubercular agent-19 is an antitubercular agent. antitubercular agent-19 showed good antitubercular effects against MTB H37Rv and MDR-MTB (MIC <0.016 μg/ml). antitubercular agent-19 showed low cytotoxicity and relatively high acute lethality in BALB/c mice. Antitubercular agent-19 exhibited low cytotoxicity and relatively high acute lethal toxicity in BALB/c mice.
价 格：￥电议型 号：T63945产 地：中国大陆
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T63904ATX inhibitor 19；化合物 ATX inhibitor 19ATX inhibitor 19
ATX inhibitor 19 is a potent inhibitor of ATX (IC50: 156 nM).
价 格：￥电议型 号：T63904产 地：中国大陆
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T63660Anti-inflammatory agent 19；化合物 Anti-inflammatory agent 19Anti-inflammatory agent 19
Anti-inflammatory agent 19 inhibits NO (IC50: 36.00 μM). anti-inflammatory agent 19 exhibits an inhibitory effect on HMGB1-induced late inflammatory responses. anti-inflammatory agent 19 can be used to study late inflammatory diseases such as Coronavirus disease (COVID-19), sepsis, etc.
价 格：￥电议型 号：T63660产 地：中国大陆
