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T79309Antibacterial agent 149;化合物 Antibacterial agent 149Antibacterial agent 149
Compd 3j (Antibacterial agent 149) is a laccase inhibitor that exhibits potent fungicidal activity, particularly useful in researching rice sheath blight [1].
价 格:¥电议型 号:T79309产 地:中国大陆
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T79306ATM Inhibitor-9;化合物 ATM Inhibitor-9ATM Inhibitor-9
ATM Inhibitor-9 (Compd 7a) is a potent inhibitor of ATM kinase, exhibiting an IC50 value of 5 nM, and is utilized in cancer research [1].
价 格:¥电议型 号:T79306产 地:中国大陆
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T79121ATR-IN-29;化合物 ATR-IN-29ATR-IN-29
ATR-IN-29, a potent, orally active inhibitor of ATR kinase, exhibits an IC50 of 1 nM and demonstrates antiproliferative activity [1].
价 格:¥电议型 号:T79121产 地:中国大陆
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T79087Antifungal agent 59;化合物 Antifungal agent 59Antifungal agent 59
Antifungal agent 59 exhibits potent activity, reflected by MIC values ranging from 0.01 to 1 μg/mL, and inhibits the formation of fungal biofilms, while maintaining safety [1].
价 格:¥电议型 号:T79087产 地:中国大陆
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T79021GSK3839919A;化合物 GSK3839919AGSK3839919A
GSK3839919A is a potent allosteric inhibitor of HIV-1 integrase [1].
价 格:¥电议型 号:T79021产 地:中国大陆
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T7894Tazarotenic acid;化合物AGN-190299AGN-190299;6-[2-(3,4-二氢-4,4-二甲基-2H-1-苯并噻喃-6-基)乙炔基]-3-吡啶甲酸|||AGN-190299
Tazarotenic acid (AGN-190299) is a retinoid prodrug which is converted to its active form
价 格:¥电议型 号:T7894产 地:中国大陆
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T78905AChE-IN-29;化合物 AChE-IN-29AChE-IN-29
AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric eel acetylcholinesterase (eeAChE), and equine butyrylcholinesterase (eqBChE), exhibiting IC50 values of 0.25 μM, 0.23 μM, and 0.72 μM, respectively. It is utilized in Alzheimer´s disease research [1].
价 格:¥电议型 号:T78905产 地:中国大陆
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T78817AChE-IN-39;化合物 AChE-IN-39AChE-IN-39
AChE-IN-39 (Compound 7c), with an IC50 value of 0.058 μM, is an acetylcholinesterase (AChE) inhibitor known for its DPPH scavenging activity and potential to ameliorate cognitive impairments in an aluminum chloride (AlCl3)-induced amnesia animal model, suggesting its usefulness in Alzheimer´s disease research [1].
价 格:¥电议型 号:T78817产 地:中国大陆
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T78780Anticancer agent 139;化合物 Anticancer agent 139Anticancer agent 139
Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating high efficacy against SNB-19, OVCAR-8, and NCI-H460 with PGIs of 86.61, 85.26, and 75.99, respectively. Moreover, it shows moderate activity against a range of other cancer cell lines — HOP-62, SNB-75, ACHN, NCI/ADR-RES, 786-O, A549/ATCC, HCT-116, and MDA-MB-231 — with PGIs between 51.88 and 67.55 [1].
价 格:¥电议型 号:T78780产 地:中国大陆
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T78527ASO 556089;化合物 ASO 556089ASO 556089
ASO 556089, a 16-nucleotide antisense oligonucleotide (3-10-3 gap protein), targets the long non-coding RNA MALAT1 in both humans and mice. It has the sequence 5´-GmCATTmCTAATAGmCAGmC-3´ [1].
价 格:¥电议型 号:T78527产 地:中国大陆
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T78116Antifungal agent 49;化合物 Antifungal agent 49Antifungal agent 49
Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].
价 格:¥电议型 号:T78116产 地:中国大陆
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T77566(3aR,9aR)-Fluparoxan;化合物(3aR, 9aR)-Fluparoxan(3aR,9aR)-Fluparoxan
(3aR,9aR)-Fluparoxan is a highly selective and potent adrenergic receptor α2B antagonist for the prevention, amelioration or treatment of neurodevelopmental disorders and neurodegenerative diseases.
价 格:¥电议型 号:T77566产 地:中国大陆
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T7749ALB-127158;化合物 T7749ALB-127158
ALB-127158(a) is a potent and selective melanin concentrating hormone 1 ( MCH 1 ) receptor antagonist which may be a potential treatment for inflammatory bowel disease (IBD).
价 格:¥电议型 号:T7749产 地:中国大陆
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T7681AZD-5069;化合物AZD-5069AZD-5069
AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).
价 格:¥电议型 号:T7681产 地:中国大陆
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T76580Antioxidant agent-9;化合物 Antioxidant agent-9Antioxidant agent-9
Antioxidant Agent-9, a peptide featuring the Asp-Trp sequence, exhibits antioxidant properties and demonstrates potential as an antiviral against SARS-CoV-2, possessing an affinity strength comparable to that of Chloroquine and Favipiravir [1] [2].
价 格:¥电议型 号:T76580产 地:中国大陆
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T76244Amp1EP9;化合物 Amp1EP9Amp1EP9
Amp1EP9, an antimicrobial peptide, serves as a potent and non-toxic candidate for the development of effective antimicrobial agents. It holds promise for research into multidrug-resistant bacterial infections [1].
价 格:¥电议型 号:T76244产 地:中国大陆
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T7556Fadrozole hydrochloride;盐酸法倔唑CGS 16949A;CGS 16949A|||盐酸法倔唑
Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.
价 格:¥电议型 号:T7556产 地:中国大陆
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T75152ARC19499;化合物 ARC19499ARC19499
ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor Xa and the TF/factor VIIa complex, thereby correcting thrombin generation in hemophilia A and B plasma and restoring clotting in FVIII-neutralized whole blood.
价 格:¥电议型 号:T75152产 地:中国大陆
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T75067Antimalarial agent 19;化合物 Antimalarial agent 19Antimalarial agent 19
Antimalarial agent 19 (compound 6e) exhibits antimalarial activity against the blood stages of P. falciparum K1 and P. berghei, with EC50 values of 0.3 ?M and 15.3 ?M, respectively. It demonstrates good aqueous solubility, intestinal permeability, and microsomal stability relative to gamhepathiopine [1].
价 格:¥电议型 号:T75067产 地:中国大陆
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T749899AzNue5Ac;化合物 9AzNue5Ac9AzNue5Ac
9-Azido-9-deoxy-N-acetylneuraminic acid (9AzNue5Ac) serves as a click chemistry reagent and an analogue of Neu5Ac, featuring an azide substitution for the 9-hydroxyl group. This compound is capable of being metabolized and integrated into sialoglycans within living cells and mice. Due to its advantages such as high yield, specificity, and ease of use, click chemistry, facilitated by reagents like 9AzNue5Ac, is extensively utilized across various research domains for the efficient linkage of nucl
价 格:¥电议型 号:T74989产 地:中国大陆