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  • T74972A2-Iso5-4DC19；化合物 A2-Iso5-4DC19A2-Iso5-4DC19

    A2-Iso5-4DC19, a lipidoid compound, effectively facilitates the delivery of agents, including polynucleotides, to cells [1].

    价 格：￥电议型 号：T74972产 地：中国大陆

  • T74954Antimicrobial agent-9；化合物 Antimicrobial agent-9Antimicrobial agent-9

    Antimicrobial Agent-9 (Compound 16) exhibits antimicrobial properties with a minimum inhibitory concentration (MIC) range of 4-8 μg/mL against both gram-positive and gram-negative bacteria, and also demonstrates anti-inflammatory activity [1].

    价 格：￥电议型 号：T74954产 地：中国大陆

  • T74776Antibacterial agent 139；化合物 Antibacterial agent 139Antibacterial agent 139

    Antibacterial agent 139 exhibits antibacterial activity specifically targeting Gram-positive bacteria, including resistant strains such as MRSA (anti-MRSA), VISA (anti-VISA), and LRSE (anti-LRSE). It operates by depolarizing the bacterial cell membrane [1].

    价 格：￥电议型 号：T74776产 地：中国大陆

  • T74769Antituberculosis agent-9；化合物 Antituberculosis agent-9Antituberculosis agent-9

    Antituberculosis agent-9 (Compound 5a), an orally administered compound, demonstrates potent antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 0.5 μg/mL against H37Ra [1].

    价 格：￥电议型 号：T74769产 地：中国大陆

  • T74622Antibacterial agent 109；化合物 Antibacterial agent 109Antibacterial agent 109

    Compound C-2 (Antibacterial agent 109) is a potent antibacterial agent effective against both gram-positive and gram-negative bacteria. It is non-mutagenic and functions by inhibiting protein synthesis, specifically by preventing the extension of new peptide chains [1].

    价 格：￥电议型 号：T74622产 地：中国大陆

  • T74526Antifungal agent 29；化合物 Antifungal agent 29Antifungal agent 29

    Antifungal Agent 29 (compound 9d) is a potent, selective, and non-toxic agent effective against Cryptococcus neoformans, exhibiting an MIC of ≤0.23 μM [1].

    价 格：￥电议型 号：T74526产 地：中国大陆

  • T73833Anticancer agent 39；化合物 Anticancer agent 39Anticancer agent 39

    Anticancer Agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), not only induces apoptosis through the collapse of mitochondrial membrane potential (MMP) but also inhibits cell cloning and migration, demonstrating promising anti-proliferative activity against HGC-27 cells with an IC50 value of 0.39 μM [1].

    价 格：￥电议型 号：T73833产 地：中国大陆

  • T7375A-836339；化合物A-836339A-836339

    A-836339 acts as a potent cannabinoid receptor full agonist which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 receptor (Ki = 270 nM). It displays analgesic, anti-inflammatory, and anti-hyperalgesic effects in mice.

    价 格：￥电议型 号：T7375产 地：中国大陆

  • T73529AS-99；化合物 AS-99AS-99

    AS-99 is a first-in-class, potent, and selective inhibitor of the ASH1L histone methyltransferase, exhibiting anti-leukemic activity with an IC50 value of 0.79 ?M and a Kd of 0.89 ?M. It inhibits cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and effectively reduces leukemia burden in vivo.

    价 格：￥电议型 号：T73529产 地：中国大陆

  • T73395ASPER-29；化合物 ASPER-29ASPER-29

    ASPER-29, an analog of Asperphenamate, acts as a dual inhibitor of cathepsin L and S, displaying inhibitory concentrations (IC50) of 6.03 μM and 5.02 μM, respectively. This compound is utilized in the study of cancer migration and invasion.

    价 格：￥电议型 号：T73395产 地：中国大陆

  • T73356Ac32Az19；化合物 Ac32Az19Ac32Az19

    Ac32Az19 is a potent, non-toxic, and highly selective inhibitor of Breast Cancer Resistance Protein (BCRP), demonstrating an EC50 of 13 nM in BCRP-overexpressed HEK293/R2 cells.

    价 格：￥电议型 号：T73356产 地：中国大陆

  • T73345AP 24149；化合物 AP 24149AP 24149

    AP 24149, a potent dual inhibitor targeting Src and Abl, exhibits IC50 values of 9.1 nM for Src and 3.6 nM for Abl, respectively.

    价 格：￥电议型 号：T73345产 地：中国大陆

  • T73245AChE-IN-9；化合物 AChE-IN-9AChE-IN-9

    AChE-IN-9, a Tacrine glycoconjugate connected to acetylated β-Glucose, acts as an AChE inhibitor, demonstrating an IC 50 value of 0.4 μM and exhibiting reduced hepatotoxicity in healthy cells. This compound finds use in Alzheimer´s research [1].

    价 格：￥电议型 号：T73245产 地：中国大陆

  • T7317CU-CPT-9a；化合物CU-CPT-9aCU-CPT-9a

    CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-

    价 格：￥电议型 号：T7317产 地：中国大陆

  • T73100ACT-606559；化合物 ACT-606559ACT-606559

    ACT-606559, a metabolite of ACT451840, is a novel chemical compound exhibiting antimalarial properties. It is utilized in malaria research.

    价 格：￥电议型 号：T73100产 地：中国大陆

  • T72920Azaphilone-9；化合物 Azaphilone-9AZA-9；AZA-9

    Azaphilone-9 (AZA-9) functions as an inhibitor of the HuR-ARE RNA interaction, with an inhibition constant (IC50) of 1.2 μM, by targeting the RNA-binding protein Hu antigen R (HuR). As HuR-RNA interactions play a critical role in stabilizing oncogenic mRNAs within tumors, Azaphilone-9 exhibits potential in inhibiting cancer cell growth and progression.

    价 格：￥电议型 号：T72920产 地：中国大陆

  • T72690AMPK activator 9；化合物 AMPK activator 9AMPK activator 9

    AMPK Activator 9 (ZM-6), a potent activator of AMPK (α2β1γ1), demonstrates an EC50 of 1.1 ?M, indicating its strong efficacy in activating AMPK. This compound holds promise for type 2 diabetes research, highlighting its potential application in understanding and possibly treating this condition.

    价 格：￥电议型 号：T72690产 地：中国大陆

  • T72593Antiviral agent 9；化合物 Antiviral agent 9Antiviral agent 9

    Antiviral agent 9 exhibits potent efficacy against HIV-1 with an EC50 value of 0.006 nM, indicating extremely low concentrations are sufficient to inhibit the virus. Additionally, it demonstrates a selectivity index (SI) nearly 300 times higher than that of tenofovir alafenamide fumarate (TAF), outlining its superior selectivity and potential safety profile.

    价 格：￥电议型 号：T72593产 地：中国大陆

  • T72487Anticancer agent 99；化合物 Anticancer agent 99Anticancer agent 99

    Anticancer agent 99 exhibits potent anticancer activity towards HepG2 cells, evidenced by an IC50 value of 35.9 μM. It effectively induces apoptosis and inhibits cell proliferation.

    价 格：￥电议型 号：T72487产 地：中国大陆

  • T72476Anticancer agent 59；化合物 Anticancer agent 59Anticancer agent 59

    Anticancer agent 59, an inhibitor active against various cancer cell lines, particularly demonstrates efficacy in A549 cells with an IC 50 value of 0.2 μM. It prompts apoptosis, elevates Ca2+ and ROS levels within cancer cells, and markedly reduces mitochondrial membrane potential. Additionally, it effectively curtails tumor growth in the A549 mouse xenograft model.

    价 格：￥电议型 号：T72476产 地：中国大陆

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