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T83057Anti-inflammatory agent 49;化合物 Anti-inflammatory agent 49Anti-inflammatory agent 49
Compound SC9, an anti-inflammatory agent, serves as a potent and selective inhibitor of the Drp1-Fis1 interaction, mitigating FIS1-mediated mitochondrial dysfunction. It exhibits an in vitro IC50 value of 270 nM for inhibiting GTPase activity [1].
价 格:¥电议型 号:T83057产 地:中国大陆
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T83053Anti-inflammatory agent 59;化合物 Anti-inflammatory agent 59Anti-inflammatory agent 59
Anti-inflammatory agent 58 is characterized by its ability to inhibit IL-1β with an IC50 value of 2.28 μM. Furthermore, it reduces pro-inflammatory gene expression, protein secretion, and NF-κB phosphorylation [1].
价 格:¥电议型 号:T83053产 地:中国大陆
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T83025Antiparasitic agent-19;化合物 Antiparasitic agent-19Antiparasitic agent-19
Antiparasitic Agent-19 (Compound 40) is a broad-spectrum antiparasitic with minimal toxicity to Trypanosoma brucei, Leishmania infantum, and Trypanosoma cruzi [1].
价 格:¥电议型 号:T83025产 地:中国大陆
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T83018Antiproliferative agent-39;化合物 Antiproliferative agent-39Antiproliferative agent-39
Antiproliferative Agent-39 (Compound 12) effectively inhibits the proliferation of various cancer cell lines, including A549, SNU-638, Col2, HT1080, and MCF-7, with respective IC50 values of 11, 25, 14, 11, and 6.3 μM [1].
价 格:¥电议型 号:T83018产 地:中国大陆
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T83008Antitumor agent-119;化合物 Antitumor agent-119Antitumor agent-119
Antitumor agent-119 (compound 13K), a 2-benzoxazolyl hydrazone derivative, exhibits anticancer capabilities by impeding the proliferation of Burkitt, CCRF-CEM, HeLa, and HT-29 cells, with respective IC50 values of 30 nM, 140 nM, 100 nM, and 40 nM [1].
价 格:¥电议型 号:T83008产 地:中国大陆
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T83006Antitumor agent-29;化合物 Antitumor agent-29Antitumor agent-29
Antitumor agent-29 is a hepatocyte-targeting prodrug with demonstrated efficacy and minimal toxicity in anticancer applications.
价 格:¥电议型 号:T83006产 地:中国大陆
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T83004Antitumor agent-39;化合物 Antitumor agent-39Antitumor agent-39
Antitumor Agent-39 is a peptide-based compound with anticancer properties[1].
价 格:¥电议型 号:T83004产 地:中国大陆
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T83002Antitumor agent-49;化合物 Antitumor agent-49Antitumor agent-49
Antitumor agent-49 (Compound 10), a harmine derivative-furoxan hybrid featuring nitric oxide (NO) donating properties, exhibits cytotoxic effects against HepG2 cells, achieving an IC50 value of 1.79 ?M and inducing significant NO production in vitro [1].
价 格:¥电议型 号:T83002产 地:中国大陆
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T83000Antitumor agent-89;化合物 Antitumor agent-89Antitumor agent-89
Antitumor agent-89 (Compd OTS-5), a naturally occurring compound, exhibits weak inhibitory activity against fMLP-induced superoxide generation [1].
价 格:¥电议型 号:T83000产 地:中国大陆
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T82960ASC-69;化合物 ASC-69APY69;APY69
ASC-69 (APY69) is a promising potent inhibitor of the PD-1/PD-L1 signaling pathway, classified as a small-molecule compound [1].
价 格:¥电议型 号:T82960产 地:中国大陆
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T82901Belrestotug;化合物 BelrestotugGSK4428859A|||EOS884448|||EOS-448;GSK4428859A|||EOS884448|||EOS-448
Belrestotug (EOS-448), an antagonistic anti-TIGIT (VSIG9, VSTM3) antibody of the human immunoglobulin G1 kappa (hIgG1 kappa) class, exhibits antineoplastic activity [1].
价 格:¥电议型 号:T82901产 地:中国大陆
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T82637Cyclorasin 9A5;化合物 Cyclorasin 9A5Cyclorasin 9A5
Cyclorasin 9A5 is a cell-permeable, 11-residue cyclic peptide that orthosterically disrupts the Ras-Raf protein interaction, demonstrating an inhibition concentration (IC50) of 120 nM [1].
价 格:¥电议型 号:T82637产 地:中国大陆
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T80200Acetyl hexapeptide-49;化合物 Acetyl hexapeptide-49Acetyl hexapeptide-49
Acetyl hexapeptide-49 is a bioactive peptide recognized for its anti-allergenic properties, commonly utilized as a cosmetic ingredient [1].
价 格:¥电议型 号:T80200产 地:中国大陆
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T79774Antibacterial agent 159;化合物 Antibacterial agent 159Antibacterial agent 159
Compound 6d (Antibacterial agent 159) is an antibiotic effective against impetigo and Clostridium difficile infection (CDI), with no observed recurrence for CDI and minimal impact on the beneficial gut microbiome [1].
价 格:¥电议型 号:T79774产 地:中国大陆
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T79551Antifungal agent 69;化合物 Antifungal agent 69Antifungal agent 69
Antifungal agent 69 (compound 13), a eugenol-imidazole derivative, demonstrates targeted activity against Candida albicans with a minimum inhibitory concentration (MIC) of 4.6 μM, while exhibiting negligible cytotoxicity. This compound disrupts ergosterol biosynthesis, contributing to its antifungal efficacy [1].
价 格:¥电议型 号:T79551产 地:中国大陆
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T79534Antimalarial agent 29;化合物 Antimalarial agent 29Antimalarial agent 29
Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P. berghei liver stage parasite load, exhibiting an effective concentration (EC50) of 5.2 μM [1].
价 格:¥电议型 号:T79534产 地:中国大陆
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T79461YK-029A;化合物 YK-029AYK-029A
YK-029A, an orally active EGFR mutant inhibitor, targets both EGFR T790M and EGFRex20ins mutations. It demonstrates notable antitumor efficacy, inducing tumor regression in EGFRex20ins-driven patient-derived xenograft (PDX) models [1].
价 格:¥电议型 号:T79461产 地:中国大陆
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T79449Antileishmanial agent-19;化合物 Antileishmanial agent-19Antileishmanial agent-19
Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L. donovani promastigotes, demonstrating an IC50 of 3.39 μM. It functions by inhibiting the Leishmania prolyl-tRNA synthetase and disrupting the host PI3K/Akt/CREB axis-mediated IL-10 secretion. Additionally, Compound F27 promotes autophagy-mediated apoptosis in L. donovani promastigotes and has been shown to reduce parasite burden in L.d-infected animals [1].
价 格:¥电议型 号:T79449产 地:中国大陆
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T79379Antitubercular agent-39;化合物 Antitubercular agent-39Antitubercular agent-39
Antitubercular agent-39 (Compound P1) is a potent agent effective against both drug-resistant strains and drug-susceptible clinical isolates of tuberculosis, exhibiting inhibition of the Mtb strain H37Rv with a minimum inhibitory concentration (MIC) of less than 1 μM [1].
价 格:¥电议型 号:T79379产 地:中国大陆
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T79363APG-2449;化合物 APG-2449APG-2449
APG-2449 is an orally active inhibitor targeting ALK, ROS1, and FAK, demonstrating antitumor efficacy in mouse models of non-small cell lung cancer (NSCLC) [1].
价 格:¥电议型 号:T79363产 地:中国大陆