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  • T63373S100A2-p53-IN-1；化合物 S100A2-p53-IN-1S100A2-p53-IN-1

    S100A2-p53-IN-1 (compound 51), an inhibitor of S100A2-p53 interactions, targets S100A2, a Ca 2+ binding protein involved in cell signaling and commonly upregulated in pancreatic cancer. This compound effectively inhibits the growth of the MiaPaCa-2 pancreatic cancer cell line, showing a growth inhibition (GI 50) range of 1.2-3.4 μM [1].

    价 格：￥电议型 号：T63373产 地：中国大陆

  • T63260Snail/HDAC-IN-1；Snail/HDAC 抑制剂1Snail/HDAC-IN-1

    Snail/HDAC-IN-1 is a Snail/HDAC inhibitor agent with antimicrobial and anticancer activity, reduces Snail protein expression, induces apoptosis, and can be used in the study of solid tumors.

    价 格：￥电议型 号：T63260产 地：中国大陆

  • T63156SJ000025081；化合物 SJ000025081SJ000025081

    SJ000025081 is a dihydropyridine and can be used as an antimalarial agent. In a mouse malaria model, SJ000025081 significantly inhibited parasitemia in P. yoelii infection.

    价 格：￥电议型 号：T63156产 地：中国大陆

  • T63090SMCypI C31；化合物 SMCypI C31SMCypI C31

    SMCypIC31 is a non-peptide cyclophilin inhibitor that effectively inhibits peptidyl-prolyl cis/trans isomerase (PPIase) (IC50: 0.1 μM). SMCypI C31 has a pan-genotypic effect against HCV, with an EC50 range of 1.20-7.76 μM against genotypes 1a, 1b, 2a, 3a and 5a HCV-SGRs and chimeric genotypes 2a/4a HCV-SGRs.

    价 格：￥电议型 号：T63090产 地：中国大陆

  • T63086SYK/JAK-IN-1；化合物 SYK/JAK-IN-1SYK/JAK-IN-1

    SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.

    价 格：￥电议型 号：T63086产 地：中国大陆

  • T63045(1S,3R)-GNE-502；化合物 (1S,3R)-GNE-502(1S,3R)-GNE-502

    (1S,3R)-GNE-502 (compound 179) is a potent degradation agent of Erα and is able to degrade ERα in MCF7 HCS cells (EC50: 13 nM). (1S,3R)-GNE-502 can be used in the study of estrogen receptor-related cancers.

    价 格：￥电议型 号：T63045产 地：中国大陆

  • T62958SARS-CoV-2-IN-31；化合物 SARS-CoV-2-IN-31SARS-CoV-2-IN-31

    SARS-CoV-2-IN-31 is a potent inhibitor of COVID-19. SARS-CoV-2-IN-31 shows excellent to mild activity (IC50: 28.84-38.36 μM) against a variety of cancer cell lines. SARS-CoV-2-IN-31 can be used in cancer research.

    价 格：￥电议型 号：T62958产 地：中国大陆

  • T62830SGLT1/2-IN-1；化合物 SGLT1/2-IN-1SGLT1/2-IN-1

    SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor.

    价 格：￥电议型 号：T62830产 地：中国大陆

  • T62829SARS-CoV-2 nsp14-IN-1；化合物 SARS-CoV-2 nsp14-IN-1SARS-CoV-2 nsp14-IN-1

    SARS-CoV-2 nsp14-IN-1 (Compound 3) is a typical dual-substrate inhibitor of SARS-CoV-2Nsp14 Mtase (IC50: 0.061 μM). Histone lysine, protein arginine, DNA and RNA, etc.).

    价 格：￥电议型 号：T62829产 地：中国大陆

  • T62757SID7970631；化合物 SID7970631SID7970631

    SID7970631 is an isoquinolinone analogue, a selective and potent submicromolar SF-1 inhibitor with an IC50 of 260 nM. SID7970631 can be used to study cancer.

    价 格：￥电议型 号：T62757产 地：中国大陆

  • T62536S100P-IN-1；S100P抑制剂1S100P-IN-1

    S100P-IN-1 is a potent S100P inhibitor.S100P-IN-1 has anti-metastatic effects on pancreatic cancer (pancreatic) cells.

    价 格：￥电议型 号：T62536产 地：中国大陆

  • T62471SGC agonist 1；化合物 SGC agonist 1SGC agonist 1

    SGC agonist 1 is a potent soluble guanylate cyclase (SGC) agonist. SGC agonist 1 is able to increase solubility and has high cell permeability.

    价 格：￥电议型 号：T62471产 地：中国大陆

  • T62413SARS-CoV-2 nsp13-IN-1；化合物 SARS-CoV-2 nsp13-IN-1SARS-CoV-2 nsp13-IN-1

    SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent inhibitor of nsp13 (non-structural protein 13). SARS-CoV-2 nsp13-IN-1 inhibits only nsp13 ssDNA+ATPase (IC50: 6 μM), but not ssDNA-ATPase. CoV-2 nsp13-IN-1 was able to be used to study COVID-19.

    价 格：￥电议型 号：T62413产 地：中国大陆

  • T62240Sirt1/2-IN-1；化合物 Sirt1/2-IN-1Sirt1/2-IN-1

    Sirt1/2-IN-1 (Compound 7) is an inhibitor of SIRT1 and SIRT2 and is capable of acting on SIRT1 (IC50: 1.81 μg/mL), SIRT2 (IC50: 2.10 μg/mL) and SIRT3 (IC50: 20.5 μg/mL) and has α-microtubulin hyperacetylation activity ( Sirt1/2-IN-1 exhibited significant anticancer effects.

    价 格：￥电议型 号：T62240产 地：中国大陆

  • T61992SIK1 activator 1；化合物 SIK1 activator 1SIK1 activator 1

    SIK1 activator 1 can enhances the SIK1 phosphorylation and ameliorated the hyperglyceamia of type 2 diabetic mice. SIK1 activator 1 exhibited remarkable inhibitory activity on hepatic gluconeogenesis.

    价 格：￥电议型 号：T61992产 地：中国大陆

  • T61965SphK1-IN-1；化合物 SphK1-IN-1SphK1-IN-1

    SphK1-IN-1 is an inhibitor of SphK1 with anti-tumor activity. SphK1-IN-1 inhibits the ATPase of SphK1, IC50=2.48 μM. SphK1-IN-1 has the value of cancer research.

    价 格：￥电议型 号：T61965产 地：中国大陆

  • T61897SMO-IN-1；化合物 SMO-IN-1SMO-IN-1

    SMO-IN-1 (Compound 15) is an oral effective Smoothened (SMO) inhibitor. The EC50 value of sonic Hh protein (shh) is 89 nM.

    价 格：￥电议型 号：T61897产 地：中国大陆

  • T61841SCD1-IN-1；化合物 SCD1-IN-1SCD1-IN-1

    SCD1-IN-1, a potent inhibitor of SCD1 (IC50: 5.8 nM), is valuable in dermatologic research [1].

    价 格：￥电议型 号：T61841产 地：中国大陆

  • T61774SARS 3CLpro-IN-1；化合物 SARS 3CLpro-IN-1SARS 3CLpro-IN-1

    SARS 3CLpro-IN-1 (Compound 3b) is a stereo-specific SARS 3CL protease inhibitor that belongs to the octahydroisochromene scaffold. It demonstrates inhibition against the P1 site imidazole, with an IC50 value of 95 μM [1].

    价 格：￥电议型 号：T61774产 地：中国大陆

  • T61716Steroid sulfatase/17β-HSD1-IN-1；化合物 Steroid sulfatase/17β-HSD1-IN-1Steroid sulfatase/17β-HSD1-IN-1

    Steroid sulfatase/17β-HSD1-IN-1 is a highly effective inhibitor of both steroid sulfatase and 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) activities, displaying an IC50 value of 28 nM against cellular human steroid sulfatase. This compound holds significant potential for investigating estrogen-dependent diseases [1].

    价 格：￥电议型 号：T61716产 地：中国大陆

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