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T16291NF157；化合物 T16291NF157
NF157 significantly decreases the expression of metalloproteinase (MMP)-3, MMP-13, which can be used in the treatment of osteoarthritis (OA). NF157 is a highly selective nanomolar P2Y11 antagonist (pKi: 7.35). The IC50s are 463 nM, 1811 μM, 170 μM for P2Y11 (Ki=44.3 nM), P2Y1 (Ki=187 μM), P2Y2 (Ki=28.9 μM), respectively.
价 格：￥电议型 号：T16291产 地：中国大陆
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T15803LY223982化合物 T15803SKF107324|||CGS23131
LY223982 is an effective and specific inhibitor of the leukotriene B4 receptor (IC50: 13.2 nM). It also can against [3H]LTB4 binding to LTB4 receptor.
价 格：￥电议型 号：T15803产 地：中国大陆
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T15661Kif15-IN-1；化合物 T15661Kif15-IN-1
Kif15-IN-1, a mitotic Kinesin family member 15 (Kif15) inhibitor, is utilized in the study of cellular proliferative diseases.
价 格：￥电议型 号：T15661产 地：中国大陆
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T15409GNF179；化合物GNF179GNF179
GNF179 is an optimized 8,8-dimethyl IP analog. It exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.
价 格：￥电议型 号：T15409产 地：中国大陆
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T15266F16；化合物F16(E)-4-(3-indolylvinyl)-N-methylpyridinium iodide；(E)-4-(3-indolylvinyl)-N-methylpyridinium
F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.
价 格：￥电议型 号：T15266产 地：中国大陆
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T15239Epristeride；爱普列特SKF105657|||ONO-9302；SKF105657|||ONO-9302
Epristeride (ONO-9302) is an orally active, selective and non-competitive steroidal 5-α-reductase isoform 2 inhibitor that inhibits SR isoform 2.Episteride reduces prostate size and improves symptoms in men with BPH.Episteride induces atrophy and apoptosis of the ventral prostate in rats.
价 格：￥电议型 号：T15239产 地：中国大陆
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T14665Motixafortide化合物 T14665BL-8040|||BKT140 (4-fluorobenzoyl)|||TF14016
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).
价 格：￥电议型 号：T14665产 地：中国大陆
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T13460(+)-Cevimeline hydrochloride hemihydrate；化合物 T13460(+)-AF102B hydrochloride hemihydrate|||(+)-SNI-20
(+)-Cevimeline hydrochloride hemihydrate ((+)-SNI-2011), a potent muscarinic receptor agonist, stands as a promising therapeutic candidate for treating xerostomia in Sjogren´s syndrome. This compound has demonstrated a broad pharmacological profile across various systems including gastrointestinal, urinary, and reproductive, in animal models such as mice, rats, guinea pigs, rabbits, and dogs. Its metabolism was assessed in vitro using rat and dog liver microsomes, revealing that (+)-SNI-20
价 格：￥电议型 号：T13460产 地：中国大陆
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T13421(-)-Cevimeline hydrochloride hemihydrate；化合物 T13421(-)-SNI-2011|||(-)-AF102B hydrochloride hemihydra
Cevimeline hydrochloride hemihydrate ((-)-SNI-2011), a novel muscarinic receptor agonist, is being explored as a potential treatment for xerostomia in Sjogren´s syndrome, exhibiting an IC50 value indicative of its affinity for mAChR. This compound´s pharmacological effects on the gastrointestinal, urinary, and reproductive systems, alongside its impact on various tissues, were thoroughly examined in species including mice, rats, guinea pigs, rabbits, and dogs. The metabolic breakdown
价 格：￥电议型 号：T13421产 地：中国大陆
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T13324VUF11207 fumarate；化合物VUF11207 fumarateVUF11207 fumarate
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
价 格：￥电议型 号：T13324产 地：中国大陆
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T13194CSF1R-IN-2；化合物CSF1R-IN-2CSF1R-IN-2
CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).
价 格：￥电议型 号：T13194产 地：中国大陆
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T126048Coreanoside F1；化合物 Coreanoside F1Coreanoside F1
Coreanoside F1 is a useful organic compound for research related to life sciences. The catalog number is T126048 and the CAS number is 132282-69-0.
价 格：￥电议型 号：T126048产 地：中国大陆
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T125155Schidigerasaponin F1；化合物 Schidigerasaponin F1Schidigerasaponin F1
Schidigerasaponin F1 is a useful organic compound for research related to life sciences. The catalog number is T125155 and the CAS number is 266998-42-9.
价 格：￥电议型 号：T125155产 地：中国大陆
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T12223Nifursemizone；硝呋米腙NF161|||5-Nitro-2-furancarbaldehyde 2-ethyl semicarbazone|||Etafurazone；NF161|||5-
Nifursemizone (Etafurazone) is an agent with antiprotozoal.
价 格：￥电议型 号：T12223产 地：中国大陆
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T12125MuRF1-IN-1；化合物MuRF1-IN-1MuRF1-IN-1
MuRF1-IN-1 is an inhibitor of muscle ring finger 1.
价 格：￥电议型 号：T12125产 地：中国大陆
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T11759Kif15-IN-2；化合物 T11759Kif15-IN-2
Kif15-IN-2 is used for the research of cellular proliferative diseases. Kif15-IN-2 is an inhibitor of the mitotic kinesin Kif15.
价 格：￥电议型 号：T11759产 地：中国大陆
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T11445GNF179 (Metabolite)；化合物 T11445GNF179 Metabolite；GNF179 Metabolite
GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral bioavailability.
价 格：￥电议型 号：T11445产 地：中国大陆
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T11210EP1013；化合物 T11210F1013；F1013
EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.
价 格：￥电议型 号：T11210产 地：中国大陆
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T10894CSF1R-IN-1；化合物CSF1R-IN-1CSF1R-IN-1
CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.
价 格：￥电议型 号：T10894产 地：中国大陆
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T10529BF-168化合物 T10529BF168|||BF 168
BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).
价 格：￥电议型 号：T10529产 地：中国大陆
