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T61158Anti-infective agent 5;化合物 Anti-infective agent 5Anti-infective agent 5
Anti-infective agent 5 (compound 74) is an orally active inhibitor of Trypanosoma cruzi exhibiting an IC50 value of 0.10 μM. In addition to its potent inhibitory effect, anti-infective agent 5 demonstrates efficacy in reducing parasite burden in vivo. Consequently, this compound holds promising potential for research pertaining to infection. [1]
价 格:¥电议型 号:T61158产 地:中国大陆
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T61096Antibacterial agent 95;化合物 Antibacterial agent 95Antibacterial agent 95
Antibacterial agent 95 (2-(quinoline-4-methoxy) acetamide), a new antituberculotic agent, exhibited a minimum inhibitory concentration (MIC) of only 0.3 μM against the reference strain of Mycobacterium tuberculosis H37Rv. Additionally, it effectively suppressed the growth of Mycobacterium tuberculosis in the macrophage model of tuberculosis infection.
价 格:¥电议型 号:T61096产 地:中国大陆
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T60998Anticancer agent 75;化合物 Anticancer agent 75Anticancer agent 75
Anticancer agent 75 has good antiplasmodial activity. Anticancer agent 75 is a potent anticancer agent with cytotoxicity and selectivity in cancer cell lines. The cytotoxicity of Anticancer agent 75 to normal human kidney cell lines is at least 35 times lower than that of the Doxorubicin standard [1].
价 格:¥电议型 号:T60998产 地:中国大陆
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T60945Antitubercular agent-15;化合物 Antitubercular agent-15Antitubercular agent-15
Antitubercular agent-15 (Compound 5n) is an antitubercular agent with low cytotoxicity against pulmonary fibroblasts and macrophages. The MIC90 values of Antitubercular agent-15 against M. tuberculosis H37Rv, CF16, CF61, CF76, CF152 and CF161 are 0.73, 7.69, 9.38, 18.80, 7.53 and 7.31 μg/mL, respectively [1].
价 格:¥电议型 号:T60945产 地:中国大陆
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T60915A1AR antagonist 5;化合物 A1AR antagonist 5A1AR antagonist 5
A1AR antagonist 5 (compound 20) is a potent and selective antagonist of A1 adenosine receptor (A1AR) with a pKi of 6.11 and a pIC 50 of 5.83 [1].
价 格:¥电议型 号:T60915产 地:中国大陆
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T60897Aldose reductase-IN-5;化合物 Aldose reductase-IN-5Aldose reductase-IN-5
Aldose reductase-IN-5 is an inhibitor of aldose reductase (ALR2) that enhances the combination of inhibitory excitability and antioxidant capacity, thereby delaying the diabetes complications progress.
价 格:¥电议型 号:T60897产 地:中国大陆
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T60666Antibacterial agent 105;化合物 Antibacterial agent 105Antibacterial agent 105
Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones. Antibacterial agent 105 exhibits antibacterial activity against M. tuberculosis with MIC 90 of 2.64 μM. Moreover, Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC 90 s of 11.18, 11.18,0.70,1.40,44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes and S. aureus, respectively [1].
价 格:¥电议型 号:T60666产 地:中国大陆
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T60560Anti-inflammatory agent 15;化合物 Anti-inflammatory agent 15Anti-inflammatory agent 15
Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial agent that can be used in the research of tuberculosis (TB). Anti-inflammatory agent 15 inhibits the growth of Mtb H37Rv and M299 with MIC50 of 2.3 and 7.8 μM, respectively. Anti-inflammatory agent 15 (compound 29) is also an anti-inflammatory agent that inhibits NO by suppressing the expression of iNOS and also inhibited the production of TNF-α and IL-1β [1].
价 格:¥电议型 号:T60560产 地:中国大陆
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T60537ARUK3001185;化合物 ARUK3001185ARUK3001185
ARUK3001185 (Compound 8l) is a potent, selective, orally active, and brain-penetrant Notum inhibitor(IC50 = 6.7 nM) that is suitable for oral dosing in rodent models of disease [1].
价 格:¥电议型 号:T60537产 地:中国大陆
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T60500AP-C5;化合物AP-C5AP-C5
AP-C5 is a compound with selective inhibition of guanosine 3´,5´ cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), with a Pic50 value of 7.2 for cGMP, and can be used in the study of diarrheal diseases.
价 格:¥电议型 号:T60500产 地:中国大陆
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T60455Antibacterial agent 65;化合物 Antibacterial agent 65Antibacterial agent 65
Antibacterial agent 65 is a potential antimicrobial agent and antioxidant agent.
价 格:¥电议型 号:T60455产 地:中国大陆
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T5A2461Bufotalin蟾蜍他灵蟾蜍他灵|||Bufotaline|||蟾毒它灵,蟾蜍他灵
1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.
价 格:¥电议型 号:T5A2461产 地:中国大陆
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T5A2455Arenobufagin沙蟾毒精沙蟾毒精|||沙蟾毒经
Arenobufagin is a natural bufadienolide from toad venom with potent antineoplastic activity against HCC HepG2 cells and corresponding multidrug-resistant HepG2/ADM cells.
价 格:¥电议型 号:T5A2455产 地:中国大陆
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T55565a-Pregnane-3,20-dione;氢化黄体酮5a-Pregnane-3,20-dione
5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone
价 格:¥电议型 号:T5556产 地:中国大陆
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T5520LCetrorelix diacetate;醋酸西曲瑞克NS-75A|||SB-075 acetate|||SB-075 diacetate|||Cetrorelix acetate|||NS-75A
Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist. It works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
价 格:¥电议型 号:T5520L产 地:中国大陆
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T5434ARV-825;化合物ARV-825ARV-825
ARV-825, a heterobifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon leading to fast, efficient, and prolonged degradation of BRD4 in all BL cell lines tested.
价 格:¥电议型 号:T5434产 地:中国大陆
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T4471E7449;化合物E7449Stenoparib|||UNII-9X5A2QIA7C;Stenoparib|||UNII-9X5A2QIA7C
E7449 (UNII-9X5A2QIA7C) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ~50 and ~50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
价 格:¥电议型 号:T4471产 地:中国大陆
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T40891ADTL-SA1215;ADTL-SA1215ADTL-SA1215;ADTL-SA1215
ADTL-SA1215 is a novel, highly selective small-molecule compound that acts as a specific activator of SIRT3, a protein known to play a crucial role in modulating autophagy. This compound holds great potential in the treatment of triple-negative breast cancer, as it effectively targets the molecular pathways associated with this subtype of cancer.
价 格:¥电议型 号:T40891产 地:中国大陆
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T40330Anticancer agent 15;Anticancer agent 15Anticancer agent 15
Anticancer agent 15, an anticancer agent, exerts its efficacy by elevating intracellular levels of reactive oxygen species (ROS) and inducing cell death in melanoma cancer cells through necroptosis.
价 格:¥电议型 号:T40330产 地:中国大陆
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T40262Antifungal agent 15;Antifungal agent 15Antifungal agent 15
Antifungal agent 15 exhibits remarkable potency, with EC50 values of 0.52 and 0.50 μg/mL against S. sclerotiorum and B. cinerea, respectively.
价 格:¥电议型 号:T40262产 地:中国大陆