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T64222Antitumor agent-55;化合物 Antitumor agent-55Antitumor agent-55
Antitumor agent-55 (compound 5q) is a potent antitumour agent that effectively inhibits PC3 (IC50: 0.91 μM). antitumor agent-55 blocks the G1/S phase of the PC3 cell cycle, induces apoptosis, inhibits cell migration and prevents the formation of PC3.
价 格:¥电议型 号:T64222产 地:中国大陆
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T64212Antiproliferative agent-5;化合物 Antiproliferative agent-5Antiproliferative agent-5
Antiproliferative agent-5 (compound 4o) irreversibly and significantly inhibits the proliferation of gastric cancer cells. antiproliferative agent-5 blocks the cell cycle in G2/M phase, induces ROS accumulation and activates cellular autophagy. Antiproliferative agent-5 can be used in anti-cancer research.
价 格:¥电议型 号:T64212产 地:中国大陆
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T64209Anticancer agent 55;化合物 Anticancer agent 55Anticancer agent 55
Anticancer Agent is a potent anti-cancer agent that exhibits anti-cancer effects by inhibiting cell viability and cell migration in a dose-dependent manner and inducing apoptosis.Anticancer Agent has potential for prostate and breast cancer research.
价 格:¥电议型 号:T64209产 地:中国大陆
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T64200C5aR-IN-2;化合物 C5aR-IN-2C5aR-IN-2
C5aR-IN-2 is a potent inhibitor of C5aR. C5aR-IN-2 has shown potential for the study of inflammatory diseases.
价 格:¥电议型 号:T64200产 地:中国大陆
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T64193AKR1C3-IN-5;化合物 AKR1C3-IN-5AKR1C3-IN-5
AKR1C3-IN-5 (Compound 6e) is a potent inhibitor of AKR1C3, derived from drupanin. AKR1C3 enzymes are overexpressed in hormone-dependent prostate and breast tumours. AKR1C3-IN-5 is able to act on MCF-7 cells (IC50: 9.6 ± 3 μM; SI: 5.5).
价 格:¥电议型 号:T64193产 地:中国大陆
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T64179Anticancer agent 65;化合物 Anticancer agent 65Anticancer agent 65
Anticancer agent 65 showed good results in tumour cell lines, especially A549 cells (IC50: 1.07 μM). anticancer agent 65 blocked the cell cycle of A549 cells in S phase, induced apoptosis, increased the expression of p53 and p21, and contributed to ROS generation and MMP collapse.
价 格:¥电议型 号:T64179产 地:中国大陆
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T64162AChE-IN-5;化合物 AChE-IN-5AChE-IN-5
AChE-IN-5 (compound 5) is an orally active, blood-brain barrier-transparent substance with significant in vitro biological activity against AChE/5-HT1A/SERT. IC50: 2.29 nM).
价 格:¥电议型 号:T64162产 地:中国大陆
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T64035Antitrypanosomal agent 5;化合物 Antitrypanosomal agent 5Antitrypanosomal agent 5
Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).
价 格:¥电议型 号:T64035产 地:中国大陆
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T64034Antitumor agent-45;化合物 Antitumor agent-45Antitumor agent-45
Antitumor agent-45 has an inhibitory effect on c-Met expression and is able to block A549 cells in the G0/G1 and G2/M phases and induce apoptosis.
价 格:¥电议型 号:T64034产 地:中国大陆
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T63968AZ14145845;化合物 AZ14145845AZ14145845
AZ14145845 is an in vivo potent and highly selective type I1/2 Mer/Axl bispecific kinase inhibitor.
价 格:¥电议型 号:T63968产 地:中国大陆
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T63923ATR-IN-5;化合物 ATR-IN-5ATR-IN-5
ATR-IN-5 is a potent inhibitor of ATR, a member of the PIKK family of proteins involved in genome stability and DNA damage repair. ATR is a member of the PIKK family, a class of protein kinases involved in genome stability and DNA damage repair, and ATR-IN-5 has shown potential for ATR kinase-mediated diseases such as proliferative diseases and cancer.
价 格:¥电议型 号:T63923产 地:中国大陆
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T63840Antibacterial agent 115;化合物 Antibacterial agent 115Antibacterial agent 115
Antibacterial agent 115 is an antibacterial and anti-inflammatory agent that is active when taken orally.
价 格:¥电议型 号:T63840产 地:中国大陆
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T63817Axl-IN-5;化合物 Axl-IN-5Axl-IN-5
Axl-IN-5 (compound 1) is an AXL inhibitor (IC50: 283 nM) that exhibits anticancer activity.
价 格:¥电议型 号:T63817产 地:中国大陆
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T63802Antifungal agent 35;化合物 Antifungal agent 35Antifungal agent 35
Antifungal agent 35 is an effective antifungal agent that potentiates the antifungal activity of fluconazole against C. albicans.
价 格:¥电议型 号:T63802产 地:中国大陆
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T63587Anticancer agent 45;化合物 Anticancer agent 45Anticancer agent 45
Anticancer agent 46 is a potent and selective anticancer agent that induces apoptosis. anticancer agent 46 exhibits cytotoxic effects in cancer cells and shows low toxicity to activated lymphocytes of human blood.
价 格:¥电议型 号:T63587产 地:中国大陆
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T63563AN-12-H5;化合物 AN-12-H5AN-12-H5
AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.
价 格:¥电议型 号:T63563产 地:中国大陆
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T63413Antimalarial agent 15;化合物 Antimalarial agent 15Antimalarial agent 15
Antimalarial agent 15 is a parasite inhibitor that exhibits antimalarial effects and inhibits the growth of Plasmodium falciparum 3D7 with an IC50 value of 20 nM.
价 格:¥电议型 号:T63413产 地:中国大陆
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T63324Androgen receptor antagonist 5;化合物 Androgen receptor antagonist 5Androgen receptor antagonist 5
Androgen receptor antagonist 5 is a potent antagonist of the androgen receptor (AR) (IC50: 6.17 μM). Androgen receptor antagonist 5 inhibited the proliferation of prostate cancer cells LNCaP and showed antitumor effect in LNCaP xenograft mice model, which can be used to study prostate cancer.
价 格:¥电议型 号:T63324产 地:中国大陆
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T63236AZD4625;化合物 AZD4625AZD4625
AZD4625 (Compound 21) is a selective, potent, orally active, covalent and mutagenic mutant GTPaseKRASG12C inhibitor.
价 格:¥电议型 号:T63236产 地:中国大陆
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T63153APJ receptor agonist 5;化合物 APJ receptor agonist 5APJ receptor agonist 5
APJ receptor agonist 5 (compound 3) is a potent and orally active apelin receptor (APJ) agonist (EC 50:0.4 nM). APJ receptor agonist 5 has excellent pharmacokinetic profiles in rodent models of heart failure (HF) and an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 can improve cardiac function and can be used in the study of HF disease.
价 格:¥电议型 号:T63153产 地:中国大陆