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T83011Antitumor agent-105;化合物 Antitumor agent-105Antitumor agent-105
Antitumor Agent-105 (Compound 37) exhibits antitumor activity, demonstrating inhibition of A549, H1299, H460, HCT116, and MDA-MB-231 cells with respective IC50 values of 6.7, 8.3, 4.3, 4.4, and 6.7 μM [1].
价 格:¥电议型 号:T83011产 地:中国大陆
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T82964ARUK2007145;化合物 ARUK2007145ARUK2007145
ARUK2007145 is a potent, cell-active inhibitor targeting both PI5P4Kα and PI5P4Kγ isoforms with pIC50 values of 7.3 and 8.1, respectively [1].
价 格:¥电议型 号:T82964产 地:中国大陆
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T82940ATTO 425;化合物 ATTO 425ATTO 425
ATTO 425 is an uncharged fluorescent dye [1].
价 格:¥电议型 号:T82940产 地:中国大陆
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T82938ATUX-1215;化合物 ATUX-1215ATUX-1215
ATUX-1215, a protein phosphatase 2A (PP2A) activator, diminishes the phosphorylation of ERK, p38, JNK, and Akt, as well as decreases the secretion of IL-12p70, GM-CSF, and IL1α in BLM-treated animals, potentially decelerating lung fibrosis progression [1].
价 格:¥电议型 号:T82938产 地:中国大陆
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T82856Blood group A antigen tetraose type 5;化合物 Blood group A antigen tetraose type 5A-Tetrasaccharide;A-T
Blood group A antigen tetraose type 5 (A-Tetrasaccharide), a tetrasaccharide specific to blood group A, inhibits the binding of anti-A antibody to blood group A substance and can be isolated from polar bear milk samples [1] [2].
价 格:¥电议型 号:T82856产 地:中国大陆
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T82797C5aR1 antagonist peptide;化合物 C5aR1 antagonist peptideC5aR1 antagonist peptide
C5aR1 antagonist peptide, a biologically active linear peptide originating from the C-terminus of the chemokine complement fragment 5 anaphylatoxin (C5a), inhibits C5a binding and activity at human and rat C5a receptors. Overexpression of C5a is linked to various immunoinflammatory diseases, including arthritis, Alzheimer’s disease, cystic fibrosis, and systemic lupus erythematosus.
价 格:¥电议型 号:T82797产 地:中国大陆
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T82762Cdc25A (80-93) (human);化合物 Cdc25A (80-93) (human)Cdc25A (80-93) (human)
Cdc25A (80-93) (human) is a polypeptide implicated in the regulation of cell proliferation and tumorigenesis through modulation of cyclin D1 expression and facilitation of the G1/S phase transition. This compound has applications in cancer research [1].
价 格:¥电议型 号:T82762产 地:中国大陆
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T8230PNU112455A hydrochloride;化合物PNU 112455APNU 112455A;PNU 112455A
PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.
价 格:¥电议型 号:T8230产 地:中国大陆
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T82161Human IgG1 (D265A) kappa, Isotype Control;化合物 Human IgG1 (D265A) kappa, Isotype ControlHuman IgG1 (D
Human IgG1 (D265A) kappa Isotype Control is a chimeric monoclonal antibody derived from both human and mouse, designed to serve as an isotype control for the human IgG1 (D265A)κ antibody.
价 格:¥电议型 号:T82161产 地:中国大陆
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T81760Mouse IgG1 (D265A) kappa, Isotype Control;化合物 Mouse IgG1 (D265A) kappa, Isotype ControlMouse IgG1 (D
Mouse IgG1 (D265A) kappa Isotype Control is a monoclonal antibody that serves as an isotype control for Mouse IgG1 (D265A) κ antibody.
价 格:¥电议型 号:T81760产 地:中国大陆
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T81755Mouse lgG2a (D265A) kappa, Isotype Control;化合物 Mouse lgG2a (D265A) kappa, Isotype ControlMouse lgG2a
Mouse IgG2a (D265A) kappa Isotype Control is a monoclonal antibody serving as an isotype control specifically for the Mouse IgG2a (D265A) antibody.
价 格:¥电议型 号:T81755产 地:中国大陆
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T81100ST8155AA1;化合物 ST8155AA1ST8155AA1
ST8155AA1, a component of antibody-drug conjugates (ADCs), is tethered to an HDAC inhibitor via a linker and exhibits antitumor activity [1].
价 格:¥电议型 号:T81100产 地:中国大陆
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T80604Duligotuzumab;化合物 DuligotuzumabRG 7597|||MEHD-7945A;RG 7597|||MEHD-7945A
Duligotuzumab (MEHD-7945A; RG 7597) is a humanized IgG-κ monoclonal antibody targeting Her3 (ErbB3) [1].
价 格:¥电议型 号:T80604产 地:中国大陆
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T80299Aurein 2.5;化合物 Aurein 2.5Aurein 2.5
Aurein 2.5, an antimicrobial peptide with antibiotic properties, exhibits both antibacterial and antifungal activities [1] [2].
价 格:¥电议型 号:T80299产 地:中国大陆
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T80265C5a Receptor agonist, mouse, human;化合物 C5a Receptor agonist, mouse, humanC5a Receptor agonist, mouse
C5a Receptor Agonist (mouse, human) is a bioactive peptide derived from the C-terminus of the complement fragment 5 anaphylatoxin (C5a), functioning as an agonist for the C5a receptor. This peptide plays a role in mediating inflammatory responses by promoting chemotaxis, leukocyte degranulation, enhanced vascular permeability, and cytokine production. Its agonistic activity is critically dependent on the presence of cyclohexylalanine at position 5 and the d-isomer of Arg at the terminal position
价 格:¥电议型 号:T80265产 地:中国大陆
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T80131C5a Anaphylatoxin (human);化合物 C5a Anaphylatoxin (human)C5a Anaphylatoxin (human)
C5a Anaphylatoxin (human) is a pro-inflammatory peptide that functions as a leukocyte chemoattractant, utilized in researching inflammation and immune responses, including allergic asthma [1] [2].
价 格:¥电议型 号:T80131产 地:中国大陆
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T79915Antioxidant agent-15;化合物 Antioxidant agent-15Antioxidant agent-15
Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM. Furthermore, it effectively inhibits tumor cell growth in Hela, Hep G2, and Caco-2 cells, with respective IC50 values of 395.26 nM, 400.4 nM, and 24.6 nM [1].
价 格:¥电议型 号:T79915产 地:中国大陆
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T79620Anti-inflammatory agent 55;化合物 Anti-inflammatory agent 55Anti-inflammatory agent 55
Compound 9j (anti-inflammatory agent 55), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression of iNOS, TNF-α, IL-6, and IL-1β. It notably suppresses LPS-induced nitric oxide (NO) production in RAW264.7 macrophages with an IC50 of 0.8 μM and demonstrates anti-inflammatory effects in vivo using a mouse auricular edema model [1].
价 格:¥电议型 号:T79620产 地:中国大陆
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T79580Antitumor agent-115;化合物 Antitumor agent-115Antitumor agent-115
Antitumor agent-115 (SS-12) is a potent anti-tumor compound, exhibiting an IC50 range of 0.34 μM-24.14 μM against the 4T1 mouse breast cancer cell line. It impedes the cell cycle, diminishes mitochondrial membrane potential, and triggers apoptosis in these cells, with an IC50 for cell viability spanning 8-25 μmol/L. This compound is applicable in breast cancer research [1].
价 格:¥电议型 号:T79580产 地:中国大陆
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T79567Antiviral agent 35;化合物 Antiviral agent 35Antiviral agent 35
Antiviral agent 35 (compound 4d) serves as a potent orally active inhibitor of the influenza virus, targeting early stages of viral replication. It suppresses influenza-induced ROS accumulation, autophagy, and apoptosis, along with the inflammatory response mediated by the RIG-1 pathway in a mouse model of pulmonary infection. Its cytotoxicity is minimal in MDCK cells, displaying a CC50 greater than 800 μM, and possesses anti-H1N1 (A/Weiss/43) activity with an EC50 of 2.28 μM [1].
价 格:¥电议型 号:T79567产 地:中国大陆