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T72468Anticancer agent 25；化合物 Anticancer agent 25Anticancer agent 25
Anticancer agent 25 demonstrates the highest level of cytotoxic effectiveness on PC3 cells, achieving an IC 50 value of 0.19 μM.
价 格：￥电议型 号：T72468产 地：中国大陆
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T72412Antimicrobial agent-5；化合物 Antimicrobial agent-5Antimicrobial agent-5
Antimicrobial Agent-5 is a potent antimicrobial agent that exhibits exceptional cell selectivity against both Gram-negative and Gram-positive bacteria. It inhibits the interaction between LPS (lipopolysaccharide) and the CD14/TLR4 (Toll-like receptor 4) receptor, demonstrating anti-inflammatory activity in combating LPS-induced inflammation.
价 格：￥电议型 号：T72412产 地：中国大陆
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T72047Antibacterial agent 125；抗菌剂125Antibacterial agent 125
Antibacterial Agent 125 exhibits potent antimicrobial activity against clinically relevant Gram-positive pathogens, displaying Minimum Inhibitory Concentration (MIC) 50 values ranging from 0.25 to 8 μM. It is suitable for researching antimicrobial resistance.
价 格：￥电议型 号：T72047产 地：中国大陆
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T71827AG-205；化合物 AG-205AG-205
(rac)-AG-205 serves as a robust inhibitor of the progesterone receptor membrane component 1 (Pgrmc1), crucial for inducing genes linked to sterol synthesis, notably the INSIG1 protein, which interacts with PGRMC1. Additionally, it plays a pivotal role in mitigating neuronal resistance to hypoxic ischaemia by inhibiting NF-kB signalling and the activation of the BDNF/PI3K/AKT pathway.
价 格：￥电议型 号：T71827产 地：中国大陆
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T71776UBTR008295a；化合物 UBTR008295aUBTR008295a
UBTR008295a is USP5 Inhibitor.
价 格：￥电议型 号：T71776产 地：中国大陆
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T71589AS15；化合物 AS15AS15
AS15 is a novel covalent nanomolar inhibitor of protein disulfide isomerase (PDI).
价 格：￥电议型 号：T71589产 地：中国大陆
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T71390AY 29315；化合物 AY 29315AY 29315
AY 29315 is a histamine H2-receptor antagonist with antisecretory and antiulcer activities.
价 格：￥电议型 号：T71390产 地：中国大陆
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T71337AJ-108235；化合物 AJ-108235AJ-108235
AJ-108235 is a novel inhibitor of long chain fatty acid elongase 6 (ELOVL6).
价 格：￥电议型 号：T71337产 地：中国大陆
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T71189RX 809055AX；化合物 RX 809055AXRX 809055AX
RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.
价 格：￥电议型 号：T71189产 地：中国大陆
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T71143Ambroxol-d5；化合物 Ambroxol-d5Ambroxol-d5
Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous part
价 格：￥电议型 号：T71143产 地：中国大陆
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T70943AM-9635；化合物 AM-9635AM-9635
AM-9635 is a potent and selective PI3Kδ inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3Kα and PI3Kβ are ubiquitously expressed and play a role in cell growth, division, and survival.
价 格：￥电议型 号：T70943产 地：中国大陆
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T70616ACT-672125；化合物 ACT-672125ACT-672125
ACT-672125 is a Potent CXCR3 Antagonist with Therapeutic Potential in Autoimmune Diseases. ACT-672125 showed good physicochemical properties and safety profile. In a proof-of-mechanism model of lung inflammation, ACT-672125 inhibited the recruitment of CXCR3 expressing T cells into the inflamed lung in a dose-dependent manner.
价 格：￥电议型 号：T70616产 地：中国大陆
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T70598ARL-67085；化合物 ARL-67085ARL-67085
ARL-67085 is a P2T (P2YADP) purinoceptor antagonist.
价 格：￥电议型 号：T70598产 地：中国大陆
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T70484AD-35；化合物 AD-35AD-35
AD-35 is a neuroprotectant for treating Alzheimer’s diseases by significantly inhibiting the production and release of proinflammatory cytokines TNF-α and IL-1β.
价 格：￥电议型 号：T70484产 地：中国大陆
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T70156K-5a2；化合物 K-5a2K-5a2
K-5a2 is a novel human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor (NNRTI).
价 格：￥电议型 号：T70156产 地：中国大陆
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T69831RPR-200765A Mesylayte；化合物 RPR-200765A MesylayteRPR-200765A Mesylayte
RPR-200765A is a potent and selective inhibitor of p38 MAP kinase (IC50 = 50 nM). It inhibits LPS-stimulated TNFalpha release both in vitro, from human monocytes (EC50 = 110 nM), and in vivo in Balb/c mice (ED50 = 6 mg/kg). At oral doses between 10 and 30 mg/kg/day it reduces the incidence and progression in the rat streptococcal cell wall (SCW) arthritis model when administered in either prophylactic or therapeutic dosing regimens. The compound, which is a mesylate salt and exists as a stable m
价 格：￥电议型 号：T69831产 地：中国大陆
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T69740AMG-315；化合物 AMG-315AMG-315
AMG-315 is a Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. AMG-315 is a chiral arachidonoyl ethanolamide (AEA) analogue or (13S,1′R)-dimethylanandamide. AMG-315 is a high affinity ligand for the CB1 receptor (Ki of 7.8 ± 1.4 nM) that behaves as a potent CB1 agonist in vitro (EC50 = 0.6 ± 0.2 nM). AMG-315 is the first potent AEA analogue with significant stability for all endocannabinoid hydrolyzing enzymes as well as the oxidative enzymes COX-2. AMG-315 will serve as a
价 格：￥电议型 号：T69740产 地：中国大陆
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T69351AD2765；化合物 AD2765AD2765
AD2765, also known as AD 2845 and Sphingosylphosphoryl? ?choline, is a novel thiourea derivative of sphingomyelin that inhibits sphingomyelin hydrolysis and synthesis, increases ceramide, and leads to cell death.
价 格：￥电议型 号：T69351产 地：中国大陆
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T69110Aseanostatin P5；化合物 Aseanostatin P5Aseanostatin P5
Aseanostatin P5 inhibits myeloperoxidase (MPO) release from human polymorphonuclear leukocytes.
价 格：￥电议型 号：T69110产 地：中国大陆
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T68984AF-399/42018025；化合物 AF-399/42018025AF-399/42018025
AF-399/42018025 is a CC chemokine receptor 4 (CCR4) antagonist.
价 格：￥电议型 号：T68984产 地：中国大陆
