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  • T62780Antiviral agent 15；化合物 Antiviral agent 15Antiviral agent 15

    Antiviral agent 15 (Compound 15f) is a Clofazimine derivative with antiviral activity.Antiviral agent 15 inhibits rabies virus (EC50: 1.45 μM) and pseudotyped SARS-CoV-2 (EC50: 14.6 μM).

    价 格：￥电议型 号：T62780产 地：中国大陆

  • T62724AQX-435；化合物 AQX-435AQX-435

    AQX-435 is a potent activator of SHIP1 (SH2 domain-containing inositol-5′-phosphatase 1). AQX-435 decreases B-cell receptor (BCR) downstream PI3K activity, induces apoptosis in malignant B cells, and exhibits inhibitory effects on lymphoma growth.

    价 格：￥电议型 号：T62724产 地：中国大陆

  • T62590AChE-IN-25；化合物 AChE-IN-25AChE-IN-25

    AChE-IN-25 is a selective, potent, non-competitive inhibitor of acetylcholinesterase (AChE) with an IC50 value of 2.95 μM. AChE-IN-25 can be used to study Alzheimer´s disease.

    价 格：￥电议型 号：T62590产 地：中国大陆

  • T62577Anti-MRSA agent 5；化合物 Anti-MRSA agent 5Anti-MRSA agent 5

    Anti-MRSA agent is a potent antagonist of MRSA (MIC50: 0.38 μg/mL) with low hERG activity (IC50: 40 μM). anti-MRSA agent also has low toxicity to mammalian cells and little potential to acquire bacterial resistance.

    价 格：￥电议型 号：T62577产 地：中国大陆

  • T62538AChE-IN-15；化合物 AChE-IN-15AChE-IN-15

    AChE-IN-15 (Compound 3d) is a reversible inhibitor of human acetylcholinesterase (huAChE) and human butyrylcholinesterase (huBChE) with IC50 values of 6.8 μM and 16.1 μM for huAChE and huBChE, respectively, with significant antioxidant activity. Alzheimer´s disease.

    价 格：￥电议型 号：T62538产 地：中国大陆

  • T62510Antitumor agent-75；化合物 Antitumor agent-75Antitumor agent-75

    Antitumor agent-75 is a novel and potent antitumor agent. antitumor agent-75 has cytotoxic effects on cancer and normal human cell lines. antitumor agent-75 in combination with antitumor agent-74 exhibits a highly selective cytotoxic effect (IC50: 2.8 μM) against human lung adenocarcinoma (cell line A549). Antitumor agent-75 can be used in cancer research.

    价 格：￥电议型 号：T62510产 地：中国大陆

  • T62393ALK5-IN-25；化合物 ALK5-IN-25ALK5-IN-25

    ALK5-IN-25 (compound EX-02) is a potent inhibitor of ALK-5 (IC50<10 nM) and also inhibits ALK-2. ALK5-IN-25 can be used in cancer research.

    价 格：￥电议型 号：T62393产 地：中国大陆

  • T62186ART615；化合物 ART615ART615

    ART615 is a related isomer of ART558. ART615 inhibits Polθ by <10% at 12 μM and is able to act as a control for ART558 (IC50:7.9 nM).

    价 格：￥电议型 号：T62186产 地：中国大陆

  • T62111Antioxidant agent-5；化合物 Antioxidant agent-5Antioxidant agent-5

    Antioxidant agent-5 (compound D-6) is a potent antioxidant. antioxidant agent-5 inhibits oxLDL-induced increases in ROS levels and NF-κB nuclear translocation. antioxidant agent-5 inhibits oxLDL (oxidized LDL)-induced apoptosis (VECs). Antioxidant agent-5 activates the Nrf2/HO-1 antioxidant pathway and exhibits protective activity against oxLDL-induced endothelial damage.

    价 格：￥电议型 号：T62111产 地：中国大陆

  • T62033Antitumor agent-65；化合物 Antitumor agent-65Antitumor agent-65

    Antitumor agent-65 (Compound 5) is an analogue/derivative of (-)-cleistenolide. Antitumor agent-65 has potential in cancer research.

    价 格：￥电议型 号：T62033产 地：中国大陆

  • T61928Antitubercular agent-25；化合物 Antitubercular agent-25Antitubercular agent-25

    Antitubercular agent-25 (Compound 28) is an anti-tubercular agent. Antitubercular agent-25 shows an extracellular IC50 of 0.42 μM and an intracellular IC50 of 0.20 μM against M. tuberculosis H37Rv. Antitubercular agent-25 shows good metabolic stability.

    价 格：￥电议型 号：T61928产 地：中国大陆

  • T61799Antibacterial agent 75；化合物 Antibacterial agent 75Antibacterial agent 75

    Antibacterial agent 75 (compound 24) possesses antibacterial properties. Its notable attribute is the ability to re-sensitize VRSA (Vancomycin-Resistant Staphylococcus aureus) strains to vancomycin, as reported in reference [1].

    价 格：￥电议型 号：T61799产 地：中国大陆

  • T61693AAK1-IN-5；化合物 AAK1-IN-5AAK1-IN-5

    AAK1-IN-5 is a potent and specific inhibitor of adaptor protein-2-associated kinase 1 (AAK1), characterized by its ability to penetrate the central nervous system and its oral bioavailability. It displays high selectivity, with an AAK1 inhibitory potency (IC 50) of 1.2 nM, a binding affinity (K i) of 0.05 nM, and an inhibitory potency against cellular AAK1 activity (cell IC 50) of 0.5 nM. AAK1-IN-5 holds promise for investigating neuropathic pain in scientific research [1].

    价 格：￥电议型 号：T61693产 地：中国大陆

  • T61680AKT-IN-5；化合物 AKT-IN-5AKT-IN-5

    AKT-IN-5 (Example 8) is a chemical compound known as an Akt inhibitor, specifically targeting Akt1 and Akt2. Its potency is reflected in IC50 values of 450 nM and 400 nM for Akt1 and Akt2, respectively [1].

    价 格：￥电议型 号：T61680产 地：中国大陆

  • T61641Antiparasitic agent-5；化合物 Antiparasitic agent-5Antiparasitic agent-5

    Antiparasitic agent-5 (compound 8h) exhibits potent selectivity as an antiparasitic agent against Leishmania infantum (L. infantum), with an IC50 value of 2.50 μM. Additionally, this compound displays cytotoxic effects on HepG2 cells with a CC50 value of 6.78 μM [1].

    价 格：￥电议型 号：T61641产 地：中国大陆

  • T61612ATX inhibitor 15；化合物 ATX inhibitor 15ATX inhibitor 15

    ATX inhibitor 15 (compound 30) is an indole-based carbamate derivative with a strong inhibitory effect on autotaxin (ATX), demonstrated by an IC50 of 2.17 nM. Additionally, ATX inhibitor 15 effectively inhibits ATX activity in vivo and suppresses the expression of pro-fibrotic genes. Furthermore, ATX inhibitor 15 exhibits protective effects in lung fibrosis induced by Bleomycin in mice [1].

    价 格：￥电议型 号：T61612产 地：中国大陆

  • T61602Anticancer agent 35；化合物 Anticancer agent 35Anticancer agent 35

    Anticancer agent 35 (compound 10), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 35 inhibits A549, A431, PACA2 cell growth with IC 50 s of 18.1 μg/mL, 4.0 μg/mL, 18.9 μg/mL, respectively [1].

    价 格：￥电议型 号：T61602产 地：中国大陆

  • T61587ATR-IN-15；化合物 ATR-IN-15ATR-IN-15

    ATR-IN-15 (compound 1) is a highly potent and orally active inhibitor of ATR kinase with an IC50 of 8 nM. Additionally, ATR-IN-15 demonstrates inhibitory activity against several targets, including human colon tumor cells LoVo, DNA-PK, and PI3K, with IC50 values of 47, 663, and 5131 nM, respectively [1].

    价 格：￥电议型 号：T61587产 地：中国大陆

  • T61560Antileishmanial agent-5；化合物 Antileishmanial agent-5Antileishmanial agent-5

    Antileishmanial agent-4 is a ribonucleoside analogue with potent activity against L.infantum and T.cruzi, having EC 50 values of 0.68 μM and 0.83 μM, respectively [1].

    价 格：￥电议型 号：T61560产 地：中国大陆

  • T61178Aβ-IN-5；化合物 Aβ-IN-5Aβ-IN-5

    Aβ-IN-5 (Compound e12) is an orally active Aβ aggregation inhibitor that also inhibits AChE and BuChE with IC50 values of 21.29 μM and 1.32 μM, respectively. Furthermore, Aβ-IN-5 exhibits remarkable neuroprotective effects along with low neurotoxicity [1].

    价 格：￥电议型 号：T61178产 地：中国大陆

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