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  • T79554AChE-IN-35；化合物 AChE-IN-35AChE-IN-35

    AChE-IN-35 (compound 5g) serves as an acetylcholinesterase inhibitor, exhibiting an inhibitory concentration 50 (IC50) value of 5.88 μM [1].

    价 格：￥电议型 号：T79554产 地：中国大陆

  • T79522Antifungal agent 65；化合物 Antifungal agent 65Antifungal agent 65

    Compound 5d (Antifungal Agent 65) exhibits potent fungicidal activity against Fusarium oxysporum f.sp. cucumerinum and is utilized in antiviral and fungicidal research [1].

    价 格：￥电议型 号：T79522产 地：中国大陆

  • T79478Anti-inflammatory agent 45；化合物 Anti-inflammatory agent 45Anti-inflammatory agent 45

    Compound 2v (Anti-inflammatory agent 45) demonstrates anticancer properties with direct inhibitory impacts on the proliferation of various blood malignancies, such as leukemia, lymphoma, and myeloma cell lines. It induces apoptosis and suppresses nitric oxide production in HL60 leukemia cells (IC50 = 14.7 μM) [1].

    价 格：￥电议型 号：T79478产 地：中国大陆

  • T79465Anticancer agent 135；化合物 Anticancer agent 135Anticancer agent 135

    Anticancer agent 135 (compound 26h) acts as a potent androgen receptor (AR) antagonist, effectively blocking AR nuclear translocation and inhibiting AR/AR-V7 heterodimerization to suppress downstream gene transcription. This compound demonstrates strong efficacy in prostate cancer xenograft models [1].

    价 格：￥电议型 号：T79465产 地：中国大陆

  • T79316Antitrypanosomal agent 15；化合物 Antitrypanosomal agent 15Antitrypanosomal agent 15

    Antitrypanosomal Agent 15 (Compound 26) is an orally active, brain-penetrant, selective inhibitor of the Trypanosoma cruzi proteasome, exhibiting a pIC50 of 7.4 for T. cruzi and <4 for the human proteasome. It possesses favorable ADME properties, rendering it useful for the study of Chagas disease [1].

    价 格：￥电议型 号：T79316产 地：中国大陆

  • T79275Antiproliferative agent-25；化合物 Antiproliferative agent-25Antiproliferative agent-25

    Antiproliferative Agent-25 (Compound 3s4) is a selective PRMT5 inhibitor displaying an IC50 of 0.11 μM. It elevates hnRNP E1 protein levels and forms hydrogen bond interactions with SAM and the E444 residue of PRMT5. This compound exhibits antiproliferative effects in A549 cells by inducing apoptosis and inhibiting migration, albeit it presents high clearance rates, with half-lives of 21.8 minutes in human liver microsomes and 4.7 minutes in rat liver microsomes [1].

    价 格：￥电议型 号：T79275产 地：中国大陆

  • T79231DSO-5a；化合物 DSO-5aDSO-5a

    DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation. It is utilized in diabetes-related research [1].

    价 格：￥电议型 号：T79231产 地：中国大陆

  • T79191AMPA receptor modulator-5；化合物 AMPA receptor modulator-5AMPA receptor modulator-5

    AMPA Receptor Modulator-5 (Example 217) serves as an AMPA receptor modulator, utilized in neurological disease research [1].

    价 格：￥电议型 号：T79191产 地：中国大陆

  • T79045AXL-IN-15；化合物 AXL-IN-15AXL-IN-15

    AXL-IN-15 (cpd391) is a potent inhibitor of Axl, exhibiting both a dissociation constant (K i) and a half-maximal inhibitory concentration (IC50) of less than 1 nanomolar (nM). It is applicable for cancer research [1].

    价 格：￥电议型 号：T79045产 地：中国大陆

  • T79024Androgen receptor-IN-5；化合物 Androgen receptor-IN-5Androgen receptor-IN-5

    Androgen receptor-IN-5 is a potent inhibitor of the androgen receptor with anticancer properties. It additionally suppresses the synthesis of IL-17A, IL-17F, and INF-γ.

    价 格：￥电议型 号：T79024产 地：中国大陆

  • T79020ALK2-IN-5；化合物 ALK2-IN-5ALK2-IN-5

    ALK2-IN-5, a pyrazolopyrimidine compound, serves as an inhibitor of ALK2 and FGFR, targeting disorders linked with their activity, including cancer [1].

    价 格：￥电议型 号：T79020产 地：中国大陆

  • T78962Antileishmanial agent-15；化合物 Antileishmanial agent-15Antileishmanial agent-15

    Antileishmanial agent-15 (compound 13c) exhibits potent activity against L. major promastigotes and amastigotes, demonstrating IC50 values of 0.78 μM for promastigotes and 0.99 μM for amastigotes, while also showing cytotoxicity at these concentrations [1].

    价 格：￥电议型 号：T78962产 地：中国大陆

  • T78957Anticancer agent 105；化合物 Anticancer agent 105Anticancer agent 105

    Anticancer agent 105, a thienopyrimidine scaffold-based compound, exhibits selective toxicity towards melanoma and induces apoptosis. Additionally, it significantly inhibits metastatic nodules, including in a pulmonary metastatic melanoma mouse model [1], while demonstrating good safety and anticancer properties.

    价 格：￥电议型 号：T78957产 地：中国大陆

  • T78828AChE/BChE-IN-15；化合物 AChE/BChE-IN-15AChE/BChE-IN-15

    AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (IC50) of 20 nM for AChE and 220 nM for BChE. It interacts with the catalytic anionic site (CAS) and the peripheral anionic site (PAS) within the enzymes´ active sites. AChE/BChE-IN-15 is applicable in Alzheimer’s disease research [1].

    价 格：￥电议型 号：T78828产 地：中国大陆

  • T78752Antibacterial agent 145；化合物 Antibacterial agent 145Antibacterial agent 145

    Compound 1b, also known as Antibacterial agent 145, targets the bacterial iron uptake pathway to exert its effects. It compromises the integrity of the bacterial cytoplasmic membrane and inhibits cellular metabolism while demonstrating minimal cytotoxicity to normal cells [1].

    价 格：￥电议型 号：T78752产 地：中国大陆

  • T78673Antibacterial agent 135；化合物 Antibacterial agent 135Antibacterial agent 135

    Antibacterial Agent 135 (example 7) effectively inhibits various bacteria, including P. aeruginosa, A. baumannii, E. coli, and K. pneumoniae, with a minimum inhibitory concentration (MIC) greater than 64 μg/mL [1].

    价 格：￥电议型 号：T78673产 地：中国大陆

  • T78556Antidepressantu00A0agentu00A05；抗抑郁剂5Antidepressantu00A0agentu00A05

    Antidepressant?agent?5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant?agent?5 acts similarly to magnoflorine in the study of depression and can be used for the prevention and treatment of depressive disorders.

    价 格：￥电议型 号：T78556产 地：中国大陆

  • T78263Anti-Mouse IFNAR1 Antibody (MAR1-5A3)；化合物 Anti-Mouse IFNAR1 Antibody (MAR1-5A3)Anti-Mouse IFNAR1 Ant

    Anti-Mouse IFNAR1 Antibody (MAR1-5A3) is a neutralizing monoclonal antibody that specifically binds to IFNAR1, blocking its signaling both in vitro and in vivo. It is of the Mouse IgG1 kappa isotype and a corresponding isotype control accompanies the antibody [1] [2].

    价 格：￥电议型 号：T78263产 地：中国大陆

  • T78069RPR132595A hydrochloride；化合物 RPR132595A hydrochlorideNPC hydrochloride；NPC hydrochloride

    RPR132595A (NPC) hydrochloride, an active metabolite of CPT-11, is produced via cytochrome P-450 3A4 (CYP3A4) metabolism and is ultimately eliminated via urinary excretion [1].

    价 格：￥电议型 号：T78069产 地：中国大陆

  • T78034ANG1005；化合物 ANG1005ANG1005

    ANG1005 is a brain-penetrating peptide-agent conjugate comprising a taxane derivative that features three paclitaxel molecules covalently bonded to Angiopep-2. This design facilitates crossing of the blood-brain and blood-cerebrospinal barriers, with subsequent penetration of malignant cells through the low-density lipoprotein receptor-related protein (LRP1) transport system [1] [2] [3].

    价 格：￥电议型 号：T78034产 地：中国大陆

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