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T27383FR-221647;化合物 T27383FR-221647
FR-221647 is a non-nucleoside adenosine deaminase inhibitor, it has moderate activity and good pharmacokinetics compared with the known inhibitors EHNA and pentostatin.
价 格:¥电议型 号:T27383产 地:中国大陆
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T27382FR-217840;化合物 T27382FR-217840
FR-217840, a novel matrix metalloproteinase inhibitor, successfully suppresses joint destruction and suggest that FR217840 may have potential as a novel anti-rheumatic drug.
价 格:¥电议型 号:T27382产 地:中国大陆
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T27381FR-202306;化合物 T27381FR202306;FR202306
FR-202306 is a inhibitor of peptide deformylase (PDF).
价 格:¥电议型 号:T27381产 地:中国大陆
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T26963CBR-2092;化合物 T26963TNP2092|||CBR2092|||TNP-2092|||TNP 2092;TNP2092|||CBR2092|||TNP-2092|||TNP 2092
CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor. CBR-2092 exhibited rifampin-like potency as an inhibitor of RNA polymerase, was an equipotent (balanced) inhibitor of DNA gyrase and DNA topoisomerase IV, and retained activity against a prevalent quinolone-resistant variant. Studies of mutant strains that exhibited reduced susceptibility to CBR-2092 further substantiated RNA polymerase as the primary cellular target of CBR-2092, with DNA gyrase and DNA topoisomerase IV b
价 格:¥电议型 号:T26963产 地:中国大陆
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T26751BBR 2160;化合物 T26751BBR-2160|||BBR2160;BBR-2160|||BBR2160
BBR 2160 is a dihydropyridine derivative belonging to the group of the so-called tiampidine. BBR 2160 has calcium-antagonistic properties in cardiac tissue. Intracellular microelectrodes have been used to characterize the electrophysiological properties of BBR 2160 on guinea-pig papillary muscle and sheep Purkinje fibres. BBR 2160 (10(-7) and 10(-6) M) dose dependently decreased the contractility of driven papillary muscle and Purkinje fibre. This effect was associated with a lowering of the pla
价 格:¥电议型 号:T26751产 地:中国大陆
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T26628Andolast;化合物 T26628CR2039|||CR-2039|||CR 2039;CR2039|||CR-2039|||CR 2039
Andolast, also known as CR-2039, an anti-allergic agent for the treatment of bronchial asthma, chronic obstructive pulmonary disease (COPD). Andolast acts at different cellular levels to inhibit immunoglobulin E synthesis. Andolast proved to be significantly more effective than placebo in improving airflow, and in controlling asthma symptoms both during day and night.
价 格:¥电议型 号:T26628产 地:中国大陆
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T26592Alfadolone acetate化合物 T26592GR 2|||GR-2|||R140|||GR2R-140
Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.
价 格:¥电议型 号:T26592产 地:中国大陆
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T26332WR23;化合物 T26332WR 23|||WR-23;WR 23|||WR-23
WR23 is a piperidinylquinoxaline derivative and a phosphoinositide 3-kinase α (PI3Kα) inhibitor.
价 格:¥电议型 号:T26332产 地:中国大陆
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T26296Triparanol;曲帕拉醇MER-29|||NSC 65345|||NSC-65345|||NSC65345;曲帕拉醇|||MER-29|||NSC 65345|||NSC-65345|||NSC
Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparanol suppresses human tumor growth and is an antilipemic agent with high ophthalmic toxicity.
价 格:¥电议型 号:T26296产 地:中国大陆
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T26096RJR-2403 oxalate;化合物 T26096RJR 2403 oxalate|||Rivanicline oxalate|||TC-2403|||Metanicotine;RJR 2403
RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.
价 格:¥电议型 号:T26096产 地:中国大陆
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T26013R 28935;化合物 T26013R-29814|||R 29814|||R29814|||R-28935|||R28935;R-29814|||R 29814|||R29814|||R-28935
R 28935 is a benzodioxan antihypertensive agent.
价 格:¥电议型 号:T26013产 地:中国大陆
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T25819ML350;化合物 T25819SR-2311|||SR 2311|||SR2311|||ML-350|||ML 350;SR-2311|||SR 2311|||SR2311|||ML-350|||M
ML350 (CYM-50202) is a KOR (IC50: 12.6 nM) antagonist with good and moderate selectivity against the DOR and MOR. CYM-50202 displayed high solubility and excellent CNS penetration. CYM-50202 did not display long-lasting pharmacodynamic effects observed with prototypical KOR antagonists.
价 格:¥电议型 号:T25819产 地:中国大陆
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T25661Lenperone;化合物 T25661Lenperonum|||AHR-2277 [as hydrochloride];Lenperonum|||AHR-2277 [as hydrochloride
Lenperone is a butyrophenone antipsychotic. Like other major tranquilizers, It has some alpha-adrenergic blocking action and is antiemetic.
价 格:¥电议型 号:T25661产 地:中国大陆
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T25489HDAC-IN-20;化合物 T25489HDACIN20|||HDAC-inhibitor-20|||HDAC inhibitor 20;HDACIN20|||HDAC-inhibitor-20||
HDAC-IN-20 is used as an HDAC inhibitor that acts by preventing HDAC-mediated diseases.
价 格:¥电议型 号:T25489产 地:中国大陆
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T25450GGTI 2147;化合物GGTI 2147GGTI2147|||Geranylgeranyl transferase inhibitor-2147|||GGTI-2147;GGTI2147|||Ge
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
价 格:¥电议型 号:T25450产 地:中国大陆
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T25440FR20;化合物 T25440FR-20|||FR 20;FR-20|||FR 20
FR20 is a human microsomal prostaglandin synthase 1 (mPGES 1) inhibitor.
价 格:¥电议型 号:T25440产 地:中国大陆
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T25432Fluspiperone;化合物 T25432NSC 354855|||NSC354855|||NSC-354855|||R-28930|||R 28930;NSC 354855|||NSC35485
Fluspiperone is an antipsychotic agent.
价 格:¥电议型 号:T25432产 地:中国大陆
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T25304Demegestone;化合物 T25304R-2453|||Lutionex|||R 2453|||RU 2453|||R2453;R-2453|||Lutionex|||R 2453|||RU 2
Demegestone is a progestin, or a synthetic progestogen, and hence is a progesterone receptor agonist, the biological target of progestogens like progesterone. It has no androgenic activity. Previously used to treat luteal insufficiency.
价 格:¥电议型 号:T25304产 地:中国大陆
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T25263Clopimozide;氯哌唑酮R-29764|||NSC-335305|||NSC 335305|||NSC335305|||R 29764;R-29764|||NSC-335305|||NSC 3
Clopimozide (R-29764) acts as a calcium channel antagonist and inhibits [3H] nilandipine binding.Clopimozide is a novel and orally available long-acting antischizophrenic psychostatic compound.
价 格:¥电议型 号:T25263产 地:中国大陆