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T72607VEGFR-2/BRAF-IN-1；化合物 VEGFR-2/BRAF-IN-1VEGFR-2/BRAF-IN-1
VEGFR-2/BRAF-IN-1, a dual inhibitor of VEGFR-2 and BRAF kinases, demonstrates potent inhibitory activity with IC50 values of 0.049 ?M for VEGFR-2, 0.063 ?M for BRAF V600E, and 0.005 ?M for BRAF WT. It effectively induces apoptosis and arrests the cell cycle primarily at the G1/S phase.
价 格：￥电议型 号：T72607产 地：中国大陆
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T72547Plm IV inhibitor-2；化合物 Plm IV inhibitor-2Plm IV inhibitor-2
Plm IV Inhibitor-2 is a powerful inhibitor of digestive vacuole plasmepsins IV (Plm IV), displaying IC50 values of 24 nM for Plm IV, 70 nM for Plm II, and 0.3 μM for Plm I. It is used in malaria research involving Plasmodium parasites.
价 格：￥电议型 号：T72547产 地：中国大陆
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T72286LC kinetic stabilizer-2；化合物 LC kinetic stabilizer-2LC kinetic stabilizer-2
LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.
价 格：￥电议型 号：T72286产 地：中国大陆
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T72195KCa1.1 channel activator-2；化合物 KCa1.1 channel activator-2KCa1.1 channel activator-2
KCa1.1 channel activator-2, a hybrid derivative of Quercetin, selectively stimulates the vascular KCa1.1 channels. This compound demonstrates significant myorelaxant activity.
价 格：￥电议型 号：T72195产 地：中国大陆
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T72135(1s,4s)-Menin-MLL inhibitor-23；化合物 (1s,4s)-Menin-MLL inhibitor-23(1s,4s)-Menin-MLL inhibitor-23
(1s,4s)-Menin-MLL Inhibitor-23, an enantiomer of Menin-MLL Inhibitor-23 (Example 99A), functions as an inhibitor of the menin-MLL interaction [1].
价 格：￥电议型 号：T72135产 地：中国大陆
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T71203JBIR-22；化合物 JBIR-22JBIR-22
JBIR-22 is a natural inhibitor for protein?protein interaction of the homodimer of proteasome assembly factor 3.
价 格：￥电议型 号：T71203产 地：中国大陆
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T7104Dovitinib lactate；多韦替尼乳酸盐CHIR-258 lactate|||TKI-258 lactate；CHIR-258 lactate|||多韦替尼乳酸盐|||TKI-258 lac
Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).
价 格：￥电议型 号：T7104产 地：中国大陆
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T69831RPR-200765A Mesylayte；化合物 RPR-200765A MesylayteRPR-200765A Mesylayte
RPR-200765A is a potent and selective inhibitor of p38 MAP kinase (IC50 = 50 nM). It inhibits LPS-stimulated TNFalpha release both in vitro, from human monocytes (EC50 = 110 nM), and in vivo in Balb/c mice (ED50 = 6 mg/kg). At oral doses between 10 and 30 mg/kg/day it reduces the incidence and progression in the rat streptococcal cell wall (SCW) arthritis model when administered in either prophylactic or therapeutic dosing regimens. The compound, which is a mesylate salt and exists as a stable m
价 格：￥电议型 号：T69831产 地：中国大陆
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T69542SIMR-2418；化合物 SIMR-2418SIMR-2418
SIMR-2418 is a SARS-CoV-2 Protease inhibitor. SIMR-2418 having an inhibitory IC50 value of 20.7 μM
价 格：￥电议型 号：T69542产 地：中国大陆
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T69402FR-226928；化合物 FR-226928FR-226928
FR-226928 is a potent antagonist of human neuropeptide Y Y5 receptors.
价 格：￥电议型 号：T69402产 地：中国大陆
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T68879FK-330 dihydrate；FK-330二水合物FR-260330 dihydrate；FR-260330 dihydrate
FK-330 dihydrate（FR-260330 dihydrate） is a novel orally active inducible nitric oxide synthase inhibitor with potential anticancer and antitumor activity to prevent ischemia and reperfusion injury in rat liver transplantation.
价 格：￥电议型 号：T68879产 地：中国大陆
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T68732FR-226928 free base；化合物 FR-226928 free baseFR-226928 free base
FR-226928 free base is a potent antagonist of human neuropeptide Y Y5 receptors.
价 格：￥电议型 号：T68732产 地：中国大陆
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T68498UCK2 Inhibitor-2；化合物 UCK2-IN-20874830UCK2 Inhibitor-2
UCK2 Inhibitor-2, a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2), exhibits an IC50 of 3.8 ?M and effectively suppresses uridine salvage within cells.
价 格：￥电议型 号：T68498产 地：中国大陆
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T68016Spiroglumide；螺谷胺CR-2194；CR-2194
Spiroglumide, a CCKB-gastrin antagonist that inhibits dose-dependent pentagastrin-induced acid hypersecretion with an ID50 of 20.1 (8.67-46.4) mg / kg, could be used to explore the physiological role of gastrin in the regulation of human gastric acid secretion.
价 格：￥电议型 号：T68016产 地：中国大陆
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T67745CB2R/FAAHu00A0modulator-2；化合物CB2R/FAAHu00A0modulator-2CB2R/FAAHu00A0modulator-2
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 has studies research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
价 格：￥电议型 号：T67745产 地：中国大陆
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T6695Tasquinimod；他喹莫德ABR-215050；他喹莫德|||ABR-215050
Tasquinimod (ABR-215050) is a quinoline-3-carboxamide linomide analog with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts.
价 格：￥电议型 号：T6695产 地：中国大陆
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T6561Laquinimod；拉喹莫德LAQ|||ABR-215062；LAQ|||ABR-215062|||拉喹莫德
Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
价 格：￥电议型 号：T6561产 地：中国大陆
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T64009HIV-1 inhibitor-23；化合物 HIV-1 inhibitor-23HIV-1 inhibitor-23
HIV-1 inhibitor-23 is a highly potent inhibitor of HIV-1 non-nucleoside reverse transcriptase, acting on both wild-type HIV-1 (EC50: 24.9 nM) and mutant strain K103N (EC50: 10.4 nM). microsomal stability in vitro.
价 格：￥电议型 号：T64009产 地：中国大陆
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T63962HIV-1 inhibitor-29；化合物 HIV-1 inhibitor-29HIV-1 inhibitor-29
HIV-1 inhibitor-29 is a potent inhibitor of HIV-1 and acts against HIV-1 IIIB (EC50: 2.18 μM). HIV-1 inhibitor-29 shows high resistance to the F227L/V106A strain with an EC50 value of 0.974 μM. HIV-1 inhibitor-29 showed low cytotoxicity against MT-4 cells with a CC50 value of 211 μM. HIV-1 inhibitor-29 can be used in AIDS research.
价 格：￥电议型 号：T63962产 地：中国大陆
