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T12746ROCK inhibitor-2;化合物ROCK inhibitor-2ROCK inhibitor-2
ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
价 格:¥电议型 号:T12746产 地:中国大陆
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T12739Rivanicline oxalate;化合物 T12739RJR-2403 oxalate|||(E)-Metanicotine oxalate;RJR-2403 oxalate|||(E)-Met
Rivanicline oxalate is an agonist of neuronal nicotinic receptor, showing high selectivity for the α4β2 subtype (Ki=26 nM).
价 格:¥电议型 号:T12739产 地:中国大陆
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T12738LRivanicline;化合物 T12738LRJR-2403|||(E)-Metanicotine;RJR-2403|||(E)-Metanicotine
Rivanicline is a neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki=26 nM). It show > 1,000 fold selectivity than α7 receptors(Ki= 36000 nM and IC50 : 26 nM).
价 格:¥电议型 号:T12738L产 地:中国大陆
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T12738Rivanicline hemioxalate;化合物 T12738RJR-2403 hemioxalate|||(E)-Metanicotine hemioxalate;RJR-2403 hemio
Rivanicline hemioxalate, also known as RJR-2403 hemioxalate or (E)-Metanicotine hemioxalate, is a chemical compound acting as a neuronal nicotinic receptor agonist with pronounced selectivity for the α4β2 receptor subtype, showing over 1,000-fold greater selectivity for this subtype (Ki=26 nM) compared to α7 receptors (Ki=3.6 μM). Its in vitro studies demonstrate no significant activation of nAChRs in PC12 cells, muscle type nAChRs, or muscarinic receptors at concentrations up to 1 mM. Furthermo
价 格:¥电议型 号:T12738产 地:中国大陆
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T12559PROTAC BET degrader-2;化合物 T12559PROTAC BET degrader-2
PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins (IC50 of 9.6 nM ).
价 格:¥电议型 号:T12559产 地:中国大陆
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T12554PROTAC EED degrader-2;化合物 T12554PROTAC EED degrader-2
PROTAC EED degrader-2 is a PROTAC targeting EED (pKD of 9.27),is a inhibitor of polycomb repressive complex 2 (PRC2) with pIC50 of 8.11.
价 格:¥电议型 号:T12554产 地:中国大陆
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T12459PI3K/mTOR Inhibitor-2;化合物PI3K/mTOR Inhibitor-2PI3K/mTOR Inhibitor-2
PI3K/mTOR Inhibitor-2 is a potent pan inhibitor of PI3K and mTOR with IC50s of 3.4, 34, 16,1 and 4.7 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR. PI3K/mTOR Inhibitor-2 has antitumor activity.
价 格:¥电议型 号:T12459产 地:中国大陆
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T12124mTOR inhibitor-2;化合物 T12124mTOR inhibitor-2
mTOR inhibitor-2 is an inhibitor of selective and oral mTOR (IC50 of 7 nM).
价 格:¥电议型 号:T12124产 地:中国大陆
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T1169Moguisteine莫吉司坦莫吉司坦|||BBR-2173
Moguisteine (BBR-2173) is a new-type peripheral non-narcotic antitussive drug.
价 格:¥电议型 号:T1169产 地:中国大陆
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T11187EMT inhibitor-2;化合物 T11187EMT inhibitor-2
EMT Inhibitor-2, targeting both CYP3A4 testosteron and CYP2C9, exhibits inhibitory effects with IC50 values of 49.72 and 5.54 μM, respectively. Furthermore, it effectively impedes the epithelial-mesenchymal transition (EMT) process, induced by immunocyte-released agents like IL-1β and TGF-β.
价 格:¥电议型 号:T11187产 地:中国大陆
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T10924Cysteine protease inhibitor-2;化合物Cysteine protease inhibitor-2Cysteine protease inhibitor-2
Cysteine protease inhibitor 2 is a cysteine protease inhibitor. Cysteine protease inhibitor 2 inhibited DCT116 and PC3 cells with GI50 values of 6.5 μM and 4.4 μM, respectively.
价 格:¥电议型 号:T10924产 地:中国大陆
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T10866Cot inhibitor-2;Cot抑制剂2Cot inhibitor-2
Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α production in human whole blood with an IC50 of 0.3 μM.
价 格:¥电议型 号:T10866产 地:中国大陆
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T10802CHMFL-EGFR-202;化合物CHMFL-EGFR-202CHMFL-EGFR-202
CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase (IC50s: 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases).
价 格:¥电议型 号:T10802产 地:中国大陆
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T10352APTO-253;化合物APTO-253LOR-253|||LT-253;LOR-253|||LT-253
APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.
价 格:¥电议型 号:T10352产 地:中国大陆
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T10123VEGFR-2-IN-9;VEGFR-2抑制剂19KDR-in-4;KDR-in-4
VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.
价 格:¥电议型 号:T10123产 地:中国大陆
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T0433Artesunate;青蒿琥酯WR-256283;WR-256283|||青蒿琥酯
Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection. It is on the World Health Organization´s List of Essential Medicines.
价 格:¥电议型 号:T0433产 地:中国大陆
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T0182Clopidogrel;氯吡格雷(S)-Clopidogrel|||SR-25990C;(S)-Clopidogrel|||SR-25990C|||氯吡格雷
Clopidogrel (SR-25990C), a P2Y12 receptor antagonist, decreases platelet aggregation.
价 格:¥电议型 号:T0182产 地:中国大陆