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T79403VEGFR-2-IN-36；化合物 VEGFR-2-IN-36VEGFR-2-IN-36
VEGFR-2-IN-36 (compound 15) serves as a potent VEGFR-2 inhibitor, exhibiting an IC50 value of 0.067 μM, and acts as an apoptosis inducer with demonstrated anticancer efficacy. It modulates apoptotic pathways by upregulating BAX and downregulating Bcl-2, leading to cytotoxic effects on cancer cell lines, including MCF-7 (IC50 = 0.42 μM) and HepG2 (IC50 = 0.22 μM) [1].
价 格：￥电议型 号：T79403产 地：中国大陆
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T79400VEGFR-2-IN-35；化合物 VEGFR-2-IN-35VEGFR-2-IN-35
VEGFR-2-IN-35 (compound 7) is a potent inhibitor of VEGFR-2, exhibiting an IC50 of 37 nM. Additionally, it demonstrates inhibitory activity against MCF-7 and HCT 116 cancer cell lines with IC50 values of 10.56 μM and 7.07 μM, respectively [1].
价 格：￥电议型 号：T79400产 地：中国大陆
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T79315PROTAC TG2 degrader-2；化合物 PROTAC TG2 degrader-2PROTAC TG2 degrader-2
PROTAC TG2 degrader-2 (compound 7) is a selective competitive degrader of Transglutaminase 2 (TG2), exhibiting a dissociation constant (Kd) greater than 100 μM. It inhibits cell migration and reduces TG2 levels in ovarian cancer cells, making it a valuable tool for ovarian cancer research [1].
价 格：￥电议型 号：T79315产 地：中国大陆
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T79284IR-251；化合物 IR-251IR-251
IR-251 is a mitochondrion-targeting near-infrared (NIR) fluorescent probe that selectively accumulates in tumor cell mitochondria through organic anion transporting polypeptides (OATPs), leading to mitochondrial dysfunction. By impeding peroxisome proliferator-activated receptor gamma (PPARγ), IR-251 promotes reactive oxygen species (ROS) overproduction, consequently inhibiting the β-catenin signaling pathway as well as associated cell cycle and metastasis proteins. This mechanism contributes to
价 格：￥电议型 号：T79284产 地：中国大陆
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T79208Oct4 inducer-2；化合物 Oct4 inducer-2Oct4 inducer-2
Oct4 Inducer-2, an OCT4 inducer, sustains hiPSC formation by enhancing endogenous OCT4 expression and has applications in anti-aging research [1].
价 格：￥电议型 号：T79208产 地：中国大陆
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T79161PROTAC PTPN2 degrader-2 TFA；化合物 PROTAC PTPN2 degrader-2 TFAPROTAC PTPN2 degrader-2 TFA
PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent degrader of Protein Tyrosine Phosphatase Non-receptor Type 2 (PTPN2), with potential applications in cancer and metabolic disease research [1].
价 格：￥电议型 号：T79161产 地：中国大陆
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T79160PROTAC PTPN2 degrader-2；化合物 PROTAC PTPN2 degrader-2PROTAC PTPN2 degrader-2
PROTAC PTPN2 degrader-2 (example 187B) is a potent agent capable of degrading PTPN2, which holds potential for research in cancer and metabolic diseases [1].
价 格：￥电议型 号：T79160产 地：中国大陆
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T79101β-Catenin modulator-2；化合物 β-Catenin modulator-2β-Catenin modulator-2
β-Catenin Modulator-2 (Compound IIa-130), which is an oxazole-thiazole derivative, serves as a potent and selective modulator of β-Catenin [1].
价 格：￥电议型 号：T79101产 地：中国大陆
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T78983STAT3 degrader-2；化合物 STAT3 degrader-2STAT3 degrader-2
STAT3 Degrader-2 is a PROTAC-based compound that effectively reduces the total STAT3 protein levels, and is utilized in the research of cancer and various diseases [1].
价 格：￥电议型 号：T78983产 地：中国大陆
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T78956PROTAC BRD3/BRD4-L degrader-2；化合物 PROTAC BRD3/BRD4-L degrader-2PROTAC BRD3/BRD4-L degrader-2
PROTAC BRD3/BRD4-L degrader-2, a PROTAC molecule, selectively degrades cellular BRD3 and BRD4-L with K i values of 16.91 and 2.8 nM, respectively, and exhibits robust antitumor activity in mouse xenograft models, serving as a research tool for cancer [1].
价 格：￥电议型 号：T78956产 地：中国大陆
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T78851BRD4 Inhibitor-28；化合物 BRD4 Inhibitor-28BRD4 Inhibitor-28
BRD4 Inhibitor-28 (Compound 18), an orally active molecule, selectively inhibits the bromodomains of BRD4 (BRD4-BD1 and BRD4-BD2) with IC50 values of 15 and 55 nM, respectively. It also demonstrates inhibition of BRD2-BD1, BRD3-BD1, and BRDT-BD1 with IC50 values of 19, 25, and 68 nM, respectively. Furthermore, this compound exhibits anti-melanoma activity [1].
价 格：￥电议型 号：T78851产 地：中国大陆
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T78819VEGFR-2-IN-33；化合物 VEGFR-2-IN-33VEGFR-2-IN-33
VEGFR-2-IN-33 (Compound 4d), a potent VEGFR inhibitor with an IC50 value of 61.04 nM, demonstrates significant inhibition of HepG2 cell proliferation, achieving an IC50 of 4.31 nM. This compound is utilized for hepatocellular carcinoma (HCC) research [1].
价 格：￥电议型 号：T78819产 地：中国大陆
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T78641ER-27319；化合物 ER-27319ER-27319
ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosine phosphorylation and enzymatic activity of SYK. With an inhibitory concentration (IC50) of 10 ?M, this compound suppresses the release of allergic mediators from human and rat mast cells triggered by antigens, making it useful for allergy research [1] [2].
价 格：￥电议型 号：T78641产 地：中国大陆
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T78555BRD4u00A0Inhibitor-27；BRD4抑制剂27BRD4u00A0Inhibitor-27
BRD4?Inhibitor-27 is a potent BRD4 inhibitor that inhibits BRD4 BD1 and BRD4 BD2 with IC50s of 9.6 and 11.3 μM, respectively.BRD4?Inhibitor-27 has anticancer activity and can be used for breast cancer research.
价 格：￥电议型 号：T78555产 地：中国大陆
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T78174Serine Hydrolase inhibitor-21；化合物 Serine Hydrolase inhibitor-21Serine Hydrolase inhibitor-21
Serine Hydrolase Inhibitor-21 (compound 8), a pyridine-based serine hydrolase inhibitor, exhibits a K i of 429 nM against BuChE, and shows promise for Alzheimer´s disease research [1].
价 格：￥电议型 号：T78174产 地：中国大陆
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T77006Felzartamab菲泽妥单抗TJ-202|||MOR-03087|||MOR-202
Felzartamab(MOR-202) is a human-targeted monoclonal antibody to CD38 for the study of multiple myeloma and advanced antibody-mediated rejection of allogeneic kidney transplants.
价 格：￥电议型 号：T77006产 地：中国大陆
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T76650PAR-2 (1-6) (human)；化合物 PAR-2 (1-6) (human)PAR-2 (1-6) (human)
PAR-2 (1-6) (human) (SLIGKV), a peptide ligand, is a PAR-2 agonist [1] .
价 格：￥电议型 号：T76650产 地：中国大陆
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T75902SLIGRL-NH2 TFA；化合物 SLIGRL-NH2 TFAProtease-Activated Receptor-2 Activating Peptide TFA；Protease-Activ
SLIGRL-NH2 TFA, also known as Protease-Activated Receptor-2 Activating Peptide TFA, is a Protease-Activated Receptor-2 (PAR-2) agonist [1].
价 格：￥电议型 号：T75902产 地：中国大陆
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T75537N-Acetyldopamine dimer-2；化合物 N-Acetyldopamine dimer-2N-Acetyldopamine dimer-2
N-Acetyldopamine dimer-2 (compound 2), an N-acetyldopamine dimer derived from the yellow powder of Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties. It notably inhibits oxidation of oxidized low-density lipoprotein (LDL), reduces reactive oxygen species (ROS) generation and nitric oxide (NO) production, and suppresses NF-κB activity [1].
价 格：￥电议型 号：T75537产 地：中国大陆
