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  • T75098HIF-PHD-IN-3；HIF-PHD抑制剂3HIF-PHD-IN-3

    HIF-PHD-IN-3 is a potent hiPSC-CM cardioprotective scaffold with potential inhibitory effects on HIF-PHD, regulates heme oxygenase-1, and can be used to study anaemia.

    价 格：￥电议型 号：T75098产 地：中国大陆

  • T75005TGFβ1-IN-3；TGFβ1抑制剂3TGFβ1-IN-3

    TGFβ1-IN-3 is a diarylhydrazone derivative with inhibitory effects on fibroblast activation and proliferation.TGFβ1-IN-3 is a candidate compound for the treatment of idiopathic pulmonary fibrosis (IPF).

    价 格：￥电议型 号：T75005产 地：中国大陆

  • T74991Dual AChE-MAO B-IN-3；化合物 Dual AChE-MAO B-IN-3Dual AChE-MAO B-IN-3

    Dual AChE-MAO B-IN-3 (Compound C10) is a potent inhibitor of both AChE and MAO-B, exhibiting IC50 values of 0.58 μM and 0.41 μM, respectively. This dual-binding inhibitor targets the catalytic anionic site and peripheral anionic site of AChE, making it relevant for Alzheimer’s disease (AD) research [1].

    价 格：￥电议型 号：T74991产 地：中国大陆

  • T74981Transketolase-IN-3；化合物 Transketolase-IN-3Transketolase-IN-3

    Transketolase-IN-3, a potent inhibitor of transketolase (TK), exhibits herbicidal activity by effectively suppressing Digitaria sanguinalis (DS) and Amaranthus retroflexus (AR). This compound holds potential for herbicide research applications [1].

    价 格：￥电议型 号：T74981产 地：中国大陆

  • T74963CypD-IN-3；化合物 CypD-IN-3CypD-IN-3

    CypD-IN-3, a potent and subtype-selective cyclophilin D (CypD) inhibitor, exhibits a high affinity for CypD with an IC50 value of 0.01 μM. It is applicable in the research of various conditions, such as oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy, and diabetes [1].

    价 格：￥电议型 号：T74963产 地：中国大陆

  • T74948LSARS-CoV-2-IN-30 disodium；化合物 SARS-CoV-2-IN-30 disodiumSARS-CoV-2-IN-30 disodium

    SARS-CoV-2-IN-30 disodium, a benzene-system-based two-armed diphosphate ester featuring molecular tweezers, demonstrates antiviral efficacy, with IC50 values of 0.6 μM against SARS-CoV-2 and 6.9 μM for spike pseudoparticle transduction, respectively. Additionally, it disrupts liposomal membranes, evidenced by an EC50 of 6.9 μM [1].

    价 格：￥电议型 号：T74948L产 地：中国大陆

  • T74948SARS-CoV-2-IN-30；化合物 SARS-CoV-2-IN-30SARS-CoV-2-IN-30

    SARS-CoV-2-IN-30, a two-armed diphosphate ester featuring a benzene system and molecular tweezers, demonstrates antiviral properties, achieving IC50 values of 0.6 μM against SARS-CoV-2 activity and 6.9 μM for spike pseudoparticle transduction. Additionally, it disrupts liposomal membranes with an EC50 of 6.9 μM [1].

    价 格：￥电议型 号：T74948产 地：中国大陆

  • T74936MDM2/4-p53-IN-3；化合物 MDM2/4-p53-IN-3MDM2/4-p53-IN-3

    MDM2/4-p53-IN-3, an inhibitor of MDM2/4-p53 protein-protein interactions (PPIs), exhibits potent activity with IC50 values of 18.5 nM for MDM2-p53 and 14.8 nM for MDM4-p53. This compound is applicable in cancer research, including studies on colon cancer [1].

    价 格：￥电议型 号：T74936产 地：中国大陆

  • T74934Trypanothione synthetase-IN-3；化合物 Trypanothione synthetase-IN-3Trypanothione synthetase-IN-3

    Trypanothione Synthetase-IN-3, a mixed noncompetitive inhibitor of Trypanothione Synthetase (TryS) with an inhibition constant (Ki) of 0.8 μM, is useful in researching parasites like L. infantum [1].

    价 格：￥电议型 号：T74934产 地：中国大陆

  • T74836MTHFD2-IN-3；化合物 MTHFD2-IN-3MTHFD2-IN-3

    MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activity of this enzyme [1].

    价 格：￥电议型 号：T74836产 地：中国大陆

  • T74828AcrB-IN-3；化合物 AcrB-IN-3AcrB-IN-3

    Efflux pump-IN-3, an AcrB efflux pump inhibitor, potentiates the effect of antibiotics by inhibiting the efflux of Nile Red (a known substrate of AcrB). It does not disrupt the bacterial outer membrane or exhibit toxicity in a nematode model [1].

    价 格：￥电议型 号：T74828产 地：中国大陆

  • T74793USP28-IN-3；USP28 抑制剂3USP28-IN-3

    USP28-IN-3 is a highly selective USP28 inhibitor with an IC50 value of 0.1 μM against USP28.USP28-IN-3 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3, and UCHL5.USP28-IN-3 is cytotoxic to human colorectal and lung squamous carcinoma cells, inhibiting c-cells and c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-cells through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellu

    价 格：￥电议型 号：T74793产 地：中国大陆

  • T74713TMV-IN-3；化合物 TMV-IN-3TMV-IN-3

    TMV-IN-3, a chalcone derivative, functions as a tobacco mosaic virus (TMV) inhibitor, exhibiting antiviral activity against TMV with an EC50 of 120.3 μg/mL. This compound is applicable for research in infection, inflammation, and tumor [1].

    价 格：￥电议型 号：T74713产 地：中国大陆

  • T74538Galectin-3 antagonist 2；化合物 Galectin-3 antagonist 2Galectin-3 antagonist 2

    Galectin-3, a β-galactoside-specific carbohydrate recognition protein (lectin), facilitates the migration of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells and demonstrates resistance to pharmaceutical interventions.

    价 格：￥电议型 号：T74538产 地：中国大陆

  • T74278HSP70-IN-3；化合物 HSP70-IN-3HSP70-IN-3

    HSP70-IN-3, a potent inhibitor of HSP70 with IC50 values of 1.1 μM in ASZ001 cells and 1.9 μM in C3H10T1/2 cells, exhibits anti-Hedgehog (Hh) signaling and anti-proliferative activities. Furthermore, it reduces the expression of the oncogenic transcription factor GLI1 [1].

    价 格：￥电议型 号：T74278产 地：中国大陆

  • T74167PCSK9-IN-3；化合物 PCSK9-IN-3PCSK9-IN-3

    PCSK9-IN-3 is a next-generation tricyclic peptide inhibitor of PCSK9, characterized by its novel structure, high potency, and oral bioavailability.

    价 格：￥电议型 号：T74167产 地：中国大陆

  • T73922Ep300/CREBBP-IN-3；化合物 Ep300/CREBBP-IN-3Ep300/CREBBP-IN-3

    Ep300/CREBBP-IN-3 (Example 61), a potent inhibitor of Ep300 and CREBBP, exhibits IC50 values of 0.056 μM and 0.095 μM, respectively. This compound is applicable in cancer research [1].

    价 格：￥电议型 号：T73922产 地：中国大陆

  • T73905SN-38 glucuronide；化合物 SN-38 glucuronideSN-38 glucuronide

    SN-38 glucuronide, an inactive metabolite of Irinotecan, serves as a derivative of this cancer-fighting agent. Irinotecan, known for inhibiting topoisomerase I, is utilized in the research of colon and rectal cancer [1].

    价 格：￥电议型 号：T73905产 地：中国大陆

  • T7353RSV604；化合物RSV604(S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)u

    RSV604 ((S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea) is an inhibitor of respiratory syncytial virus (RSV) that binds to RSV nucleoprotein (Kd = 1.31 μM)

    价 格：￥电议型 号：T7353产 地：中国大陆

  • T73353NOS-IN-3；化合物 NOS-IN-3NOS-IN-3

    NOS-IN-3 is a potent, selective, imidamide derived NOS inhibitor with an IC 50 against iNOS of 4.6 ?M, without inhibiting eNOS . NOS-IN-3 has little toxicity and can be studied in the treatment of inducible isoform involved diseases, such as septic shock [1] .

    价 格：￥电议型 号：T73353产 地：中国大陆

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